Raising Health
The History and Future of CAR T with Bruce Levine
Aug 6, 2024
Bruce Levine, a leading expert in cancer gene therapy and professor at the University of Pennsylvania, shares his insights on the evolution of CAR T-cell therapy. He reflects on his formative lab experiences that sparked his passion for translational therapies. The conversation dives into the obstacles patients face in accessing these life-saving treatments and the hope for future advancements. Levine also discusses the potential of CAR T beyond cancer and the crucial role of clinical trial volunteers in driving innovation.
31:26
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Quick takeaways
- Dr. Bruce Levine's dedication to translational therapies in cancer stemmed from personal patient interactions and transformative lab experiences.
- Despite the promise of CAR T cell therapy in treating blood cancers, significant access barriers remain, especially in underserved areas.
Deep dives
Inspiration for Translational Therapies
Dr. Bruce Levine's early experiences in a research lab at the Children's Hospital of Philadelphia fueled his passion for translational therapies in cancer. Although initially focused on other research areas, he was influenced by the direct interaction with patients and their struggles, which led him to prioritize work that would have immediate clinical implications. His hands-on experiences in laboratory settings helped him develop techniques for growing T cells efficiently, which became integral to advancements in CAR T cell therapy. His journey highlights how personal motivations and early career experiences can shape significant contributions to scientific fields.
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