Bruce Levine, a leading expert in cancer gene therapy and professor at the University of Pennsylvania, shares his insights on the evolution of CAR T-cell therapy. He reflects on his formative lab experiences that sparked his passion for translational therapies. The conversation dives into the obstacles patients face in accessing these life-saving treatments and the hope for future advancements. Levine also discusses the potential of CAR T beyond cancer and the crucial role of clinical trial volunteers in driving innovation.

Bruce Levine, co-inventor of Kymriah, and industry experts discuss CAR-T therapies, infrastructure challenges, FDA warnings on T-cell cancers post-treatment, advancements in gene editing for heart patients, cost-effective manufacturing strategies, and G-Rex technology for optimized cell production.

Historian Bruce Levine discusses Thaddeus Stevens, a revolutionary figure in the Civil War who fought for racial justice. They explore Stevens' anti-racist ideals and how he managed to be effective. The podcast covers his democratic ideology, involvement in the anti-Masonic Party, the debate between him and Lincoln, and the challenges during Reconstruction. They also discuss the importance of addressing the legacy of slavery and Jim Crow through measures like reparations.