

Harnessing Water Dynamics for Drug Design with Michael Crackower and Jason Burch
Aug 20, 2024
Michael Crackower, Chief Scientific Officer at Ventus Therapeutics, and PhD researcher Jason Burch dive into the future of drug discovery. They unveil the ReSOLVE platform, designed to quickly iterate small molecular compounds for therapeutic use. The duo discusses the importance of water dynamics in protein interactions, machine learning's role in drug design, and their strides in targeting NLRP3 for neurodegenerative diseases. With groundbreaking data and a push to enter clinical trials, they highlight the rapid progress made from concept to investigational new drug.
Chapters
Transcript
Episode notes
1 2 3 4 5
Intro
00:00 • 4min
Innovative Approaches in Drug Discovery and Small Molecule Development
04:24 • 4min
Revolutionizing Drug Design with Water Dynamics and AI
08:00 • 21min
Exploring the NLRP3 Target in Drug Development
28:53 • 5min
Rapid Advancements in Drug Development and Clinical Trials
33:55 • 4min