
The Joe Cohen Show
Unlock the secrets of your DNA and optimize your health with The Joe Cohen Show. Join Joe, biohacker and founder of SelfDecode, as he interviews world-class health experts and shares cutting-edge research and strategies for biohacking your body and brain. From functional medicine tips and supplement recommendations to longevity and performance optimization, each episode is packed with insights to help you achieve your health goals. Whether you're interested in genetics, biohacking, alternative health, or simply improving your overall wellness, this podcast has something for you. Subscribe now!
Latest episodes

Mar 7, 2025 • 45min
Whole Genome Sequencing & The Future of Health with Dr. Puya Yazdi
Is the genetics industry full of BS? Joe Cohen sits down with Dr. Puya Yazdi, co-founder of SelfDecode, to expose the real science behind genetic testing, polygenic risk scores, and why most DNA reports are giving you half-truths (or worse—total garbage).If you care about your health, longevity, and actually understanding what your genes say about you, this episode is a must-listen. Buckle up—this one's a game-changer.- Check out SelfDecode: https://selfdecode.com/- Join Joe’s online community: https://thejoecohenshow.com/

Mar 4, 2025 • 14min
Should You Take This? L. fermentum – Immunity, Glutathione and Inflammation
In this episode of The Joe Cohen Show, Joe dives into the world of probiotics and biohacking with a deep dive into Lactobacillus fermentum. He shares his personal experience megadosing this unique probiotic, which has been linked to boosting glutathione levels—one of the body's most powerful antioxidants. Joe discusses the science behind L. fermentum, its potential benefits, and whether he's noticed any significant effects. Tune in to explore the latest in supplementation, self-experimentation, and cutting-edge health optimization!- Check out SelfDecode: https://selfdecode.com/- Join Joe’s online community: https://thejoecohenshow.com/

Feb 28, 2025 • 19min
A Deep Dive into Wild Health & DNA Analysis
Explore the intriguing world of genetic reports and their limitations. Discover the common pitfalls in traditional testing, particularly with the Wild Health Report. Learn about the new 100X Wildly Healthy Functional DNA Report, which promises a more comprehensive analysis. Get insights on how to effectively interpret DNA-based diet recommendations. This discussion offers a fresh perspective on personalized health optimization and the future of biohacking in functional medicine.

Feb 25, 2025 • 18min
Choosing the Best Air Purifier And Why It Matters
Discover the surprising impact of indoor air quality on your health. Learn how mold spores, VOCs, and pollutants can drain your energy and affect your cognitive function. Get tips on selecting the best air purifier to combat these issues. Explore innovative technology designed to boost your home's air quality. This discussion empowers you to enhance your environment and reduce harmful toxins effectively.

Feb 21, 2025 • 1h 26min
Biohacking for Women: Melanie Avalon on Optimizing Health & Performance
Join host Joe Cohen as he sits down with biohacker, actress, and health influencer Melanie Avalon for an insightful discussion on women and biohacking.Melanie shares her top biohacks, secrets to boosting performance, and even some surprising drinking biohacks. As the host of multiple health-focused podcasts, founder of AvalonX, and author of What, When, Wine, Melanie brings a wealth of knowledge on intermittent fasting, paleo-style nutrition, and longevity strategies. Get 10% OFF on https://avalonx.us/ by using coupon code ‘JOE’- Check out SelfDecode: https://selfdecode.com/- Join Joe’s online community: https://thejoecohenshow.com/

Feb 18, 2025 • 24min
Should You Take This? L. Rhamnosus – GABA, Mood, and Heart Health
Dive into the fascinating world of Lactobacillus rhamnosus GG, a superstar probiotic for gut and brain health. Discover the impact of megadosing this strain, with experiences that stretch the recommended dose by 25 times! Learn how it can enhance mood and mental clarity by balancing neurotransmitters. The discussion also touches on reducing heart disease risk markers and improving digestion. Plus, insights on how personal genetics can inform probiotic choices make this an enlightening listen!

Feb 14, 2025 • 13min
Should You Take This?: B. Longum – The Probiotic for Gut & Brain Health
Delve into the world of Bifidobacterium longum and discover its astounding benefits for gut and brain health. Personal experiences highlight its effectiveness in reducing bloating and improving digestion. Scientific research supports its role in enhancing mood and immunity, while also tackling inflammation. Uncover actionable tips on integrating this powerful probiotic into your wellness routine for optimized health. It's a fascinating exploration of how a single strain can positively impact overall well-being!

Jan 10, 2025 • 15min
The Truth Behind 10X Health - DNA Deceptions #02
Dive into the murky waters of genetic testing as the discussion unpacks the flaws of the controversial 10X Genetics product. Discover why this popular service is deemed ineffective, despite its high sales and aggressive marketing. The podcast reveals the impact of misleading endorsements and the myths surrounding DNA health solutions. It's an eye-opening exploration for those navigating the often confusing world of genetic testing.

Jan 9, 2025 • 22min
Why 3x4 Genetics' Functional Approach Falls Short - DNA Deceptions #01
Dive into the world of DNA testing with a keen critique of 3x4 Genetics. Discover the flaws in functional genetics and why these assessments often miss the mark. The discussion highlights the gap between expectations and reality in genetic testing. Learn about the importance of accuracy and how advanced technologies could transform the landscape of genetic health solutions. If you're curious about what your genes really say, this conversation is packed with eye-opening insights!

Sep 20, 2024 • 39min
Best of Season 7: Highlights & Health-Changing Moments from Experts
In this special "Best of Season 7" episode, we’re revisiting the most impactful, inspiring, and thought-provoking moments from our standout interviews this season. From groundbreaking health hacks and personal growth strategies to expert insights on optimizing your life, these are the clips that sparked the biggest conversations. Whether you're a long-time listener or new to the show, this episode is packed with must-hear wisdom from our incredible guests. Tune in for a quick recap of what made Season 7 unforgettable!
- Check out SelfDecode: https://selfdecode.com/
- Join Joe’s online community: https://thejoecohenshow.com/