Delving into the controversy surrounding niacin, Joe explores its potential risks and benefits on heart health. With a focus on dosage, he navigates the biochemical effects and advocates for a balanced approach to supplementation. Personal insights and recommendations add depth to the discussion, showcasing the complexities of optimizing niacin intake for overall well-being.

The podcast discusses the role of the CNR1 gene in the endocannabinoid system, affecting mood, cognitive function, and response to cannabis. It explores how genetic variations in CB1 receptors impact stress, anxiety, memory, and decision-making. Whether you're into the science of getting high or optimizing your cannabinoid system with CBD oil, this episode has something for everyone.

Explore how serotonin influences mood and anxiety through genes like HTR1A and HTR2A. Learn how genetic variations in serotonin receptors can impact mental health and well-being. Get tips on balancing serotonin levels for improved mood and reduced anxiety.

In this episode, Joe takes questions from SelfDecode members, answering questions like: What makes SelfDecode different from other DNA companies? How does the recommendations engine work? Can you find out if a certain supplement is right for you? Plus, he shares some of his genetic predispositions and how they correlate with his lab levels! - Check out SelfDecode: https://selfdecode.com/ - Join Joe’s online community: https://thejoecohenshow.com/ 

In this episode, we delve into the critical process of methylation, highlighting its significant impact on health issues ranging from heart disease to mental health and focusing on a lesser known methylation gene - MTHFD1. We focus on the MTHFD1 gene and choline's significance beyond methylfolate and Vitamin B12 for undermethylators.  Discover how MTHFD1 impacts methylation by metabolizing tetrahydrofolate and how choline is important in supplying methyl groups.  We highlight the impact of a negative MTHFD1 variant on choline usage and the potential consequences of choline deficiency, while also stressing the importance of considering other genes involved in methylation, not just MTHFR and MTHFD1. If you're interested in learning more about how your DNA and genetics affect your health, you can: - Check out SelfDecode: https://selfdecode.com/ - Join Joe’s online community: https://thejoecohenshow.com/ 

Dr. Jack Kruse and Joe delve into biohacking water, EMFs, blue light, DHA, cold exposure, sun benefits, and sleep optimization. They challenge common health beliefs, discuss mitochondrial function, circadian biology, and the impact of non-native EMFs on health. Encouraging listeners to align with nature's design, they emphasize questioning mainstream nutritional advice and understanding the interconnectedness of biology with the environment for optimal health.

In this episode, we delve into the science behind the MAOB gene and monoamine neurotransmitters.  Join us as we explore the crucial role of dopamine, serotonin, and norepinephrine in regulating mood and cognition.  We dissect the function of the MAOB gene in metabolizing neurotransmitters and discuss the implications of genetic variations on mental health.  From increased breakdown linked to mood disorders to decreased activity associated with elevated neurotransmitter levels, we unravel the complex interplay between genes and mental well-being. If you're interested in learning more about how your DNA and genetics affect your health, you can: - Check out SelfDecode: https://selfdecode.com/ - Join Joe’s online community: https://thejoecohenshow.com/ 

Join health entrepreneurs and holistic lifestyle coaches, Lauren Sambataro and Renee Belz, aka The Biohacker Babes, as they discuss personalized wellness regimens, lab testing, hormone regulation, and advanced testing methodologies like organic acids tests and the GI MAP test. Explore the impact of stress, diet, and environment on health, optimal HRV monitoring, and functional lab tests for personalized biohacking practices.

In this episode of The Joe Cohen Show, we dive deep into the world of dopamine. We'll be focusing on the role of genetics, specifically the DRD2 gene, in regulating dopamine levels and how it affects your brain's reward system, motivation, and susceptibility to addiction. Here's what you can expect to learn: How the DRD2 gene influences dopamine D2 receptors and their impact on pleasure-seeking behaviors. Understanding the variants of the DRD2 gene and its link to dopamine receptor. How genetics can affect motivation, reward processing, and potentially lead to a dopamine imbalance. The importance of maintaining balanced dopamine levels for optimal cognitive function. Join us as we explore the fascinating world of dopamine and genetics!  If you're interested in learning more about how your DNA and genetics affect your health, you can: - Check out SelfDecode: ⁠https://selfdecode.com/⁠ - Join Joe’s online community: ⁠https://thejoecohenshow.com/⁠ 

Health experts discuss advanced health tests like VO2 max and heart rate variability, the impact of EMF and heavy metal sensitivity on health, cutting-edge wellness center AIWO, and personal experiences with health optimization. Topics include digestive enzymes, personalized supplements, and mindfulness practices for mental well-being.