Beyond the Scope

Sylvia Asa is an endocrine pathologist leading University Hospitals in Cleveland, OH into the era of digital pathology. Previously, Dr. Asa was the Head of Pathology at Canada's largest hospital network, where she successfully built a digital pathology workflow. She joins Beyond The Scope to discuss the moment of realizing the power of digitizing a slide to achieving a fully integrated digital pathology workflow in Canada's largest medical network. As a Chair of the upcoming DPA Visions Conference (October 17-19 at the MGM Grand in Las Vegas), she previews the program and highlights some of the upcoming talks. Finally, Dr. Asa gives her thoughts on what the field of pathology may look like in 10-20 years.A forum to engage with the hosts and other listeners has been launched on the DPA website www.digitalpathologyassociation.org. DPA members may login to the DPA Collaborate hub (under the Resources tab) and join the Beyond The Scope community. All listeners are encouraged to use this forum to suggest future topics and guests, submit questions and corrections, and provide general feedback.

Beyond the Scope returns as David and Giovanni discuss a publication from Archives of Pathology and Laboratory Medicine: "Digital Pathology Initiatives and Experience of a Large Academic Institution During the Coronavirus Disease 2019 (COVID-19) Pandemic". Topics include process to establish a 100% digital workflow, the remote validation process, and how the workflow was also useful for research and education. (24:49) Then, Harrison Dai (MS2, Eastern Virginia University) joins the show in a new segment sharing his experience as a medical student during the pandemic, in addition to the medical student perspective on digital pathology.Reference paper:https://meridian.allenpress.com/aplm/article/145/9/1051/464723/Digital-Pathology-Initiatives-and-Experience-of-aDPA links:https://digitalpathologyassociation.org/https://dpa-dapa.com/loginA forum to engage with the hosts and other listeners has been launched on the DPA website www.digitalpathologyassociation.org. DPA members may login to the DPA Collaborate hub (under the Resources tab) and join the Beyond The Scope community. All listeners are encouraged to use this forum to suggest future topics and guests, submit questions and corrections, and provide general feedback.

Raj and Matt join Beyond the Scope to discuss the the Digital Anatomic Pathology Academy, hosted on PathPresenter - a primarily open source cloud based viewing platform for digital slides. DAPA is used as an educational, clinical, and publication tool. DPA members can access DAPA for free to make use of the numerous educational modules (dpa-dapa.com).NOTE: this episode utilizes video for platform tutorials. Please visit https://digitalpathologyassociation.org/dpa-podcast-beyond-the-scope for the video version.2:48 Guest intro7:21 Introduction to the cloud based viewing and educational platform8:47 Tutorial for navigating the platform17:20 DAPA educational module features and demonstration20:45 DAPA use cases; including an interactive way to study for boards26:00 How DPA members and other can access the platform27:50 Open source platform vs. licensed version for private data30:10 MSKCC experience using the platform as an education portal and conference tool33:00 Long term clinical goals of the platform37:55 Utilizing the platform in underserved areas39:23 Utilizing the platform for publications and E-booksA forum to engage with the hosts and other listeners has been launched on the DPA website www.digitalpathologyassociation.org. DPA members may login to the DPA Collaborate hub (under the Resources tab) and join the Beyond The Scope community. All listeners are encouraged to use this forum to suggest future topics and guests, submit questions and corrections, and provide general feedback.

Marilyn M. Bui, MD, PhD, FCAP is a senior member in the Department of Pathology at Moffitt Cancer Center where she serves as the scientific director of the Analytic Microscopy Core. She has previously served as president of the DPA and currently chairs many committees for CAP and DPA. Dr. Bui joins Beyond the Scope to discuss her work toward digital pathology adoption and building a connected network of pathologists.1:58 Introduction and what it means to be a pathologist in the digital age6:03 Evolution of pathology toward the digital era10:18 How experience as a molecular biology researcher led to a career focused on DP/AI14:25 Building relationships through the DPA and how to get involved18:24 Highlights throughout the years of DPA leadership22:34 Global digital pathology collaborations24:23 DAPA - a cloud based platform for DP education31:05 Using social media to promote DP adoption and education32:47 Digital health initiatives at Moffitt Cancer Center36:33 Current research projects in DP/AI41:55 The future of pathology - how to improve the workforce,promote a healthy lifestyle, and decrease the workloadA forum to engage with the hosts and other listeners has been launched on the DPA website www.digitalpathologyassociation.org. DPA members may login to the DPA Collaborate hub (under the Resources tab) and join the Beyond The Scope community. All listeners are encouraged to use this forum to suggest future topics and guests, submit questions and corrections, and provide general feedback.

Chen Sagiv is an entrepreneur and computer scientist. She joins Beyond the Scope to discuss her story as a co-founder of DeePathology, a start-up providing AI tools for pathologists, as well as the challenges and excitement surrounding innovation in the digital pathology industry.3:01 Introduction7:29 Early applications of computer science in healthcare and why deep learning/AI methods are mandatory knowledge for modern computer scientists11:15 The importance of cross disciplinary work between engineers, pathologists, and computer scientists18:15 Story behind DeePathology and how the start-up helps pathologists use and understand AI tools25:47 The perceived "black box" of AI vs. DIY AI platforms31:50 Building AI algorithms from scratch37:19 Advice for innovators in the pathology spaceA forum to engage with the hosts and other listeners has been launched on the DPA website www.digitalpathologyassociation.org. DPA members may login to the DPA Collaborate hub (under the Resources tab) and join the Beyond The Scope community. All listeners are encouraged to use this forum to suggest future topics and guests, submit questions and corrections, and provide general feedback.

Dr. David Clunie is a radiologist, medical informaticist, DICOM open source software author and editor of the DICOM standard. He joins Beyond The Scope to discuss image format standards surrounding digital pathology adoption. For more information, please visit: https://www.dclunie.com/ .3:00 Intro4:15 Background on PACS and DICOM, and the importance to pathology6:39 History of DICOM as the image standard for radiology10:04 Why an image standard has yet to emerge for pathology15:38 How pathology departments can work with IT departments to aid the digital transition16:54 Clarifying misconceptions about PACS21:52 Discussing all cost elements associated with digital pathology transition27:43 Advice to pathologists regarding image archival standards long term33:20 Collaborative efforts between pathology, radiology, and IT departments37:22 Educating the pathology community on image standards and regulatory barriers44:51 The role of enterprise IT in DP adoptionA forum to engage with the hosts and other listeners has been launched on the DPA website www.digitalpathologyassociation.org. DPA members may login to the DPA Collaborate hub (under the Resources tab) and join the Beyond The Scope community. All listeners are encouraged to use this forum to suggest future topics and guests, submit questions and corrections, and provide general feedback.

Raisa Glabman is a veterinary pathologist and a fellow in the NIH/NCI Comparative Biomedical Scientist Training Program (CBSTP). Raisa joins Beyond the Scope to discuss her research on immunotherapy and the tumor microenvironment, how researchers in her field are using DP/AI, and the current state of DP adoption in veterinary medicine.2:28 Introduction4:37 NCI CBSTP program9:00 Why veterinary pathology is interested in DP/AI for clinical and research applications12:45 What human and veterinary pathologists can learn from each other regarding DP adoption16:30 DP applications in various veterinary pathology settings - industrial labs, academic centers, and small clinics20:25 Raisa's research on immunotherapy and the tumor microenvironment25:53 How Raisa is using DP/AI for her research28:10 Doing research during the pandemic29:43 Being an early adopter of DP/AI tools for this specific type of research34:50 How DP will help researchers ask new scientific questionsA forum to engage with the hosts and other listeners has been launched on the DPA website www.digitalpathologyassociation.org. DPA members may login to the DPA Collaborate hub (under the Resources tab) and join the Beyond The Scope community. All listeners are encouraged to use this forum to suggest future topics and guests, submit questions and corrections, and provide general feedback.

George Green, Head of Pharmacodiagnostics at Bristol Meyers Squibb, joins Beyond the Scope to discuss the pharmaceutical industry's perspective on digital pathology and artificial intelligence. The conversation revolves around how digital pathology will see increased applications in the current era of precision medicine.1:22 Introduction 4:15 The companion diagnostics revolution in pharma9:54 Early applications of digital pathology in pharma14:38 How the mindset of pathologists has evolved since the dawn of DP/AI19:55 Pharma perspective on how DP/AI will drive the future of precision medicine25:00 Increasing DP adoption in the pharma industry28:40 Digital pathology bringing better patient care around the worldA forum to engage with the hosts and other listeners has been launched on the DPA website www.digitalpathologyassociation.org. DPA members may login to the DPA Collaborate hub (under the Resources tab) and join the Beyond The Scope community. All listeners are encouraged to use this forum to suggest future topics and guests, submit questions and corrections, and provide general feedback.

Esther Abels, co-chair of the DPA Regulatory & Standards Task Force, has worked on the regulatory approval of digital pathology systems since the beginning. She joins Beyond The Scope to discuss her current role advancing the regulatory science of digital pathology and provides an update on the initiatives of the DPA Regulatory and Standards Task Force. Esther also discusses the excitement surrounding digital pathology for precision medicine.2:21 Introduction6:25 Early applications of digital pathology to the pharma industry8:00 Process of validating and achieving FDA approval of the first slide scanners10:00 How collaboration and teamwork help achieve regulatory approval17:48 Current initiatives of the DPA Regulatory and Standars Task Force21:40 510(k) exemption of digital pathology devices25:00 Real world data initiative and is remote sign out permanent?31:08 Using digital pathology for precision medicineA forum to engage with the hosts and other listeners has been launched on the DPA website www.digitalpathologyassociation.org. DPA members may login to the DPA Collaborate hub (under the Resources tab) and join the Beyond The Scope community. All listeners are encouraged to use this forum to suggest future topics and guests, submit questions and corrections, and provide general feedback.

Talat Zehra is a pathologist at Jinnah Sindh University in Karachi, Pakistan. Dr. Zehra joins Beyond The Scope to share how the scarcity of pathologists in Pakistan and many other regions of the world affect patient care. Dr. Zehra also discusses the advantages and challenges of bringing digital pathology to developing countries.1:00 Introduction3:30 Dr. Zehra's research with WSI in Pakistan6:15 Pathology services in Pakistan and other developing countries13:15 Pathology in rural areas of the world14:33 Benefits of digital pathology in developing countries17:42 Challenges of digital pathology adoption in developing countries19:05 Ideas for vendors and other pathologists to help increase adoption in developing countriesPlease visit other resources mentioned in this podcast:https://digitalpathologyassociation.org/blog/digital-pathology-enabling-remote-operations-during-covid-19-pandemic-and-beyond-pathologist-perception-working-in-pakistanhttps://healthcare-in-europe.com/en/news/digital-pathology-dawns-in-developing-countries.htmlA forum to engage with the hosts and other listeners has been launched on the DPA website www.digitalpathologyassociation.org. DPA members may login to the DPA Collaborate hub (under the Resources tab) and join the Beyond The Scope community. All listeners are encouraged to use this forum to suggest future topics and guests, submit questions and corrections, and provide general feedback.