Oncotarget

Explore recent cancer research on EZH2 mechanisms and cranial irradiation effects, as well as topics like molecular background of NIFTP, immunotherapy of prostate cancer, and genomic profiling of DVL1 in triple-negative breast cancer in the latest Genes & Cancer publication.

Explore the origins and impact of the Ride for Roswell event, reflecting on its history of raising funds and awareness for cancer research. Learn about Team Open Access and their dedication to fundraising for cancer research at Roswell Park Comprehensive Cancer Center.

Dr. Alexander Pohlman discusses the role of IGF-pathway biomarkers in lung cancer, focusing on their potential in risk assessment, screening, and prognosis. The podcast explores the significance of these biomarkers and their diagnostic and predictive value when combined with other screening techniques.

Discover the groundbreaking research revealing 34 novel genes linked to endocrine resistance in breast cancer, highlighting the importance and challenges of endocrine therapy for estrogen receptor positive tumors.

Researchers discuss the use of NF-κB activity to classify HPV+ head and neck cancer, highlighting the need for personalized treatment. They delve into genomic variances, TRAF3 and CYLD gene mutations, and the impact on patient outcomes. The development of a classification tool for prediction and personalized treatment strategies is crucial in improving outcomes for HPV+ HNSCC patients.

Discussion on the impact of NF Kappa B overactivation in HPV positive HNSCC, the importance of identifying TRAF3 and CYLD mutations for improved prognosis, and the use of RNA-based classification strategies.

Researchers from Louisiana State University developed CancerOmicsNet, a graph neural network model for anti-cancer drug profiling. The model integrates diverse biological data sources and shows promising results in predicting cancer cell growth after drug treatment. The study emphasizes the accuracy of CancerOmicsNet in cross-validation assessments, highlighting its potential to forecast the effects of kinase-targeted therapies on cancer cell proliferation.

The podcast discusses the impact of chromosomal translocations in cancer, focusing on the BCR-FGFR1 fusion protein in SCLL. They explore the necessary interactions of GRB2 and PLC Gamma-1 for cell proliferation and potential therapeutic interventions in BCR-FGFR1-driven hematologic malignancies.

A discussion on Impact Journals' commitment to scientific integrity in biomedical sciences, focusing on ethics, peer review, plagiarism prevention, and image forensics. They will present these processes at the SSP Annual Meeting, covering cancer research, aging, and COVID-19 vulnerability.

Explore disparities in cancer rates between genders and the search for better biomarkers and treatments in bladder cancer. Analysis of genetic variants in Polish patients with bladder and kidney cancer, revealing insights on specific variants and their impact on patient survival.