Oncotarget cover image

Oncotarget

Latest episodes

undefined
Jun 26, 2023 • 4min

DPDT Anticancer Activity in Human Colon Cancer HCT116 Cells

Exploration of Diphenyl ditelluride's anticancer activity in human colon cancer cells, including its ability to induce cell cycle arrest, DNA strand breaks, and form covalent complexes with DNA for potential anti-proliferative treatment.
undefined
Jun 21, 2023 • 4min

Targeting GITR in Cancer Immunotherapy – There Is No Perfect Knowledge

Researchers Diwakar Davar and Roberta Zappasodi discuss the potential of GITR in cancer immunotherapy, its expression on immune cells, preclinical successes, challenges in clinical translation, and understanding immune responses for novel treatments.
undefined
Jun 20, 2023 • 4min

Metformin's Role in Preventing Metabolic Syndrome During Androgen Deprivation Therapy

Researchers conducted a study on using Metformin to prevent Metabolic Syndrome during Androgen Deprivation Therapy for advanced prostate cancer. The results showed no reduction in the risk of ADT-related Metabolic Syndrome or significant changes in PSA response.
undefined
Jun 19, 2023 • 6min

Oncotarget Sponsors 2023 Ride for Roswell

Explore the history and impact of the Ride for Roswell charity bike ride event in Buffalo, NY. Learn about the significant contributions towards cancer research and patient care. Discover the fundraising rewards and team sponsorships available for the 2023 event, including support from scientific journals OncoTarget and Aging.
undefined
Jun 14, 2023 • 3min

ACSL4: Biomarker, Mediator and Target in Quadruple Negative Breast Cancer

The podcast explores the role of ACSL4 in quadruple negative breast cancer as a potential biomarker, treatment predictor, and therapeutic target. ACSL4 is a lipid metabolic enzyme differentially expressed in breast tumors, with highest expression in mesenchymal and basal-like subtypes. Researcher Marie E. Monaco discusses the potential of utilizing ACSL4 status for predicting response to treatment regimens.
undefined
Jun 12, 2023 • 3min

LP-284 Targets Non-Hodgkin's Lymphoma and DNA Damage Repair Deficiency

Researchers discuss the novel small molecule LP-284's effectiveness in targeting non-Hodgkin's lymphoma by inducing repair of DNA damage, potentially offering a promising treatment option for refractory NHL cases.
undefined
Jun 9, 2023 • 3min

Targeting the Src N-Terminal Regulatory Element in Cancer

Researchers Betlem Mezquita, Marjorie Reyes-Farias, and Miquel Pons discuss targeting the Src N-terminal regulatory element in cancer. They explore why specific inhibition of Src is crucial for effective cancer treatment and highlight the significance of the SNRE region in cancer progression and potential therapeutic implications.
undefined
Jun 7, 2023 • 3min

Value of Chemotherapy Post Immunotherapy in Stage IV Non-Small Cell Lung Cancer

Exploring the value of chemotherapy after immunotherapy for advanced lung cancer treatment. Discussing the efficacy of DASA Taxil and its impact on patients. Highlighting the evolving treatment landscape and importance of considering chemotherapy in advanced lung cancer cases.
undefined
Jun 6, 2023 • 3min

BORIS Gene Mutation and Expression: Link to Breast Cancer Progression

Researchers discuss the connection between BORIS gene mutations and breast cancer progression, revealing frequent mutations and heightened protein expression in breast carcinoma cases
undefined
May 30, 2023 • 3min

Deconstructing the Role of MALAT1 in MAPK-Signaling in Melanoma

Researchers discuss the role of MALAT1 in regulating gene and protein expression in the MAPK pathway in melanoma. Antisense oligonucleotide treatment decreases BRAF levels and MALAT1 shows increased correlation with MAPK genes in patient samples. Potential therapeutic advances in MAPK pathway regulation.

Get the Snipd
podcast app

Unlock the knowledge in podcasts with the podcast player of the future.
App store bannerPlay store banner

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode

Save any
moment

Hear something you like? Tap your headphones to save it with AI-generated key takeaways

Share
& Export

Send highlights to Twitter, WhatsApp or export them to Notion, Readwise & more

AI-powered
podcast player

Listen to all your favourite podcasts with AI-powered features

Discover
highlights

Listen to the best highlights from the podcasts you love and dive into the full episode