
Deep Tech Catalyst
Learn every week from global investors and experts how to turn your scientific discoveries into investable Deep Tech startups.
Latest episodes

Mar 28, 2025 • 28min
Private Equity Meets Deep Tech: What It Takes to Raise and Scale Beyond VC. A chat with Jean Schmitt, Managing Partner at Jolt Capital
Host: Nicola MarcheseGuest: Jean Schmitt, Managing Partner at Jolt Capital#DeepTechCatalystWatch the full conversation on our platform!Disclaimer: This content is provided solely for educational and informational purposes and should not be interpreted as financial or legal advice. Given the complexity and potential impact of these terms, it is crucial to consult with an attorney. Legal expertise is invaluable in navigating these technical aspects and ensuring that the terms are in your best interests before finalizing any agreements.

Mar 21, 2025 • 30min
Venturing into Space Health: Strategies, Insights, and Regulations for Deep Tech Startups. A chat with Erik Antonsen, SPEAR Medicine Division @ Massachusetts General Hospital
Host: Nicola MarcheseGuest: Erik Antonsen, Associate Physician and Member of the SPEAR Medicine Division in the Department of Emergency Medicine at Massachusetts General Hospital#DeepTechCatalystWatch the full conversation on our platform!Disclaimer: This content is provided solely for educational and informational purposes and should not be interpreted as financial or legal advice. Given the complexity and potential impact of these terms, it is crucial to consult with an attorney. Legal expertise is invaluable in navigating these technical aspects and ensuring that the terms are in your best interests before finalizing any agreements.

Mar 14, 2025 • 27min
How Corporate Development Teams Assess the Potential Acquisitions of Deep Tech Startups. A chat with Jun Kim, Corporate Development Director @ Zebra Technologies
Host: Nicola MarcheseGuest: Jun Kim, Corporate Development Director @ Zebra Technologies#DeepTechCatalystWatch the full conversation on our platform!Disclaimer: This content is provided solely for educational and informational purposes and should not be interpreted as financial or legal advice. Given the complexity and potential impact of these terms, it is crucial to consult with an attorney. Legal expertise is invaluable in navigating these technical aspects and ensuring that the terms are in your best interests before finalizing any agreements.

Mar 7, 2025 • 23min
Venturing into AI for the Energy Sector: Strategies & Insights for Deep Tech Startups. A chat with Felix Krause, Managing Partner @ Vireo Ventures
Host: Nicola MarcheseGuest: Felix Krause, Managing Partner at Vireo Ventures#DeepTechCatalystWatch the full conversation on our platform!Disclaimer: This content is provided solely for educational and informational purposes and should not be interpreted as financial or legal advice. Given the complexity and potential impact of these terms, it is crucial to consult with an attorney. Legal expertise is invaluable in navigating these technical aspects and ensuring that the terms are in your best interests before finalizing any agreements.

Feb 28, 2025 • 28min
Desalination and Beyond: Venturing into Water Tech. A chat with Tom Ferguson, Managing Partner @ Burnt Island Ventures
Host: Nicola MarcheseGuest: Tom Ferguson, Managing Partner at Burnt Island Ventures#DeepTechCatalystWatch the full conversation on our platform!Disclaimer: This content is provided solely for educational and informational purposes and should not be interpreted as financial or legal advice. Given the complexity and potential impact of these terms, it is crucial to consult with an attorney. Legal expertise is invaluable in navigating these technical aspects and ensuring that the terms are in your best interests before finalizing any agreements.

Feb 21, 2025 • 30min
From Lab to Market: Scaling AI and Hardware in Consumer Health. A chat with Kesar Varma, Principal @ Upfront Ventures
Host: Nicola MarcheseGuest: Kesar Varma, Principal at Upfront Ventures#DeepTechCatalystWatch the full video on our platform!Today, we’re joined by Kesar Varma, Principal at Upfront Ventures, to explore the evolving landscape of consumer healthcare, AI, and IoT. With a decade of innovation shaping biomedical devices, wearables, and AI-driven diagnostics, how can Deep Tech founders navigate market adoption, funding strategies, and business model scalability?Whether you're a startup founder, investor, or operator in the Deep Tech ecosystem, this episode is packed with practical insights on:✅ How AI and IoT are transforming healthcare—beyond fitness tracking into chronic disease management and remote patient monitoring.✅ Funding strategies for startups—balancing venture capital with regulatory considerations.✅ The B2B, B2C, and B2B2C dilemma—which model works best for consumer healthcare innovations?✅ How to navigate manufacturing, supply chain challenges, and product validation in a rapidly evolving industry.This conversation is a must-listen for anyone looking to build, invest in, or scale a hardware-based consumer healthcare solution.🎥 Watch the full conversation here: https://www.thescenarionist.com/p/scaling-ai-consumer-health-startups Disclaimer: This content is provided solely for educational and informational purposes and should not be interpreted as financial or legal advice. Given the complexity and potential impact of these terms, it is crucial to consult with an attorney. Legal expertise is invaluable in navigating these technical aspects and ensuring that the terms are in your best interests before finalizing any agreements.

Feb 14, 2025 • 29min
How to Break into Defense: Funding Strategies for Dual-Use Startups. A chat with Drew Busbee, Chief Operations Officer @ DTI
Host: Nicola MarcheseGuest: Drew Busbee, Chief Operations Officer at DTI#DeepTechCatalystWatch the full video on our platform! In this episode, we break down the critical strategies for building a successful dual-use startup—from securing venture capital and government funding to navigating customer discovery in both defense and commercial markets.Whether you're a startup founder, investor, or Deep Tech operator, this conversation provides a clear framework for balancing VC expectations with government contracts, understanding the DoD procurement process, and positioning your company for long-term success.✅ Key Questions Answered: • How do you position your product in the dual-use ecosystem?• How do you navigate government procurement?• How do you leverage non-dilutive funding?• How do you balance defense and commercial markets?• How do you align VC expectations with government funding cycles?🎥 Watch the full conversation here: https://www.thescenarionist.com/p/how-to-build-a-dual-use-startup Disclaimer: This content is provided solely for educational and informational purposes and should not be interpreted as financial or legal advice. Given the complexity and potential impact of these terms, it is crucial to consult with an attorney. Legal expertise is invaluable in navigating these technical aspects and ensuring that the terms are in your best interests before finalizing any agreements.

Feb 7, 2025 • 22min
How a Fund-of-Funds Invests: Decoding the Upstream of Venture Capital. A chat with Oscar Farres, Head of Tech VC Unit @ European Investment Fund (EIF)
Host: Nicola MarcheseGuest: Oscar Farres, Head of Tech VC Unit @ European Investment Fund (EIF)#DeepTechCatalystWatch the full video on our platform!QUICK FACTS:🚀 €3.5 Billion Deployed Annually – The EIF invests in 85-90 VC funds each year, fueling deep tech, life sciences, and climate startups across Europe.📊 The ‘Magic Triangle’ of a Strong VC Fund:✔ Team Composition – A mix of ex-entrepreneurs, operators, and finance experts.✔ Market Access – Ability to source & support high-potential startups.✔ Fund Structure – Strong portfolio strategy, follow-on reserves, and aligned incentives.📈 How to Build a VC Market from Scratch: a Case Study – In Cyprus, the EIF worked with the government to launch a brand-new venture capital ecosystem, conducting market research, structuring funds, and attracting both local & international investors.🚀 Final Thought: Europe has world-class talent, but closing the funding gap is key. Mobilizing private capital, strengthening VC ecosystems, and driving long-term investment will ensure Europe’s deep tech sector continues to thrive.#VentureCapital #DeepTech #LPs #LimitedPartners #Founders #Startups #FundOfFunds #InstitutionalInvestors #Tech #Innovation #CVC VCsDisclaimer: This content is provided solely for educational and informational purposes and should not be interpreted as financial or legal advice. Given the complexity and potential impact of these terms, it is crucial to consult with an attorney. Legal expertise is invaluable in navigating these technical aspects and ensuring that the terms are in your best interests before finalizing any agreements.

Jan 31, 2025 • 21min
In-Space Manufacturing: Challenges, Opportunities, and Strategies for Deep Tech Startups. A chat with Fathi Karouia, Senior Research Scientist @ NASA
Host: Nicola Marchese
Guest: Fathi Karouia, Senior Research Scientist @ NASA
#DeepTechCatalyst
Watch the full video on our platform!
QUICK FACTS:
🚀 The Space Economy is Booming – The World Economic Forum projects the space economy could reach $1.8 trillion by 2035, with in-space manufacturing playing a major role.
🧪 Microgravity Enables Breakthroughs – Key applications include regenerative medicine, stem cell expansion, advanced alloys, and high-quality semiconductors.
📉 Launch Costs Are Plummeting – SpaceX has lowered launch costs from $50,000/kg to ~$3,000/kg, with future costs potentially dropping to $100/kg or less.
💡 Startups Face Key Challenges – Companies must overcome technical hurdles, commercialization barriers, and supply chain logistics to scale in-space manufacturing.
💰 Funding Opportunities Exist – Non-dilutive funding sources like NASA’s InSPA, SBIR, and STTR programs can help de-risk early-stage space ventures.
🌍 From Lab to Market – Space manufacturing innovations are set to transform biomedicine, electronics, and materials science, creating high-value commercial opportunities on Earth.
#Fundraising #Startups #DeepTech #Space #SpaceEconomy #SpaceTech #VentureCapital #Startups #VCs #CVCs #PhD #Startup #Founders #Mindset #Product #Business #industry #Materials #Healthcare
Disclaimer: This content is provided solely for educational and informational purposes and should not be interpreted as financial or legal advice. Given the complexity and potential impact of these terms, it is crucial to consult with an attorney. Legal expertise is invaluable in navigating these technical aspects and ensuring that the terms are in your best interests before finalizing any agreements.

Jan 24, 2025 • 18min
Construction Tech From Lab to Market: VC Insights for Deep Tech Startups. A chat with Adarsh Sowcar, Venture Investment Manager @ Saint-Gobain NOVA
Host: Nicola Marchese
Guest: Adarsh Sowcar, Venture Investment Manager @ Saint-Gobain NOVA
#DeepTechCatalyst
Watch the full video on our platform!
KEY TAKEAWAYS:
1. By 2050, 70% of the global population will live in urban areas, driving the need for advanced construction technologies and innovative materials. People spend over 80% of their time indoors, emphasizing the importance of materials that enhance indoor air quality and comfort. The construction sector contributes nearly 40% of global CO₂ emissions, highlighting the urgency for decarbonization and sustainable practices.
2. Startups are developing materials with lower carbon footprints to enhance energy efficiency and promote circularity. The industry is adopting robotics, digitization, and offsite construction methods to improve efficiency and reduce waste. These innovations are crucial for meeting the demands of urbanization and sustainability.
3. Entrepreneurs must understand industry problems and engage with stakeholders to gather insights. Startups should demonstrate how their technology solves specific problems better than existing alternatives. Successful startups must ensure their technology integrates easily into existing workflows to minimize adoption barriers.
4. At the pre-seed stage, startups should develop a working prototype and validate the material's technical feasibility and scalability. They should also engage with industry stakeholders to gather feedback and demonstrate commercial potential. At the seed stage, conducting extensive real-world performance tests to ensure reliability and meet industry standards is crucial.
5. Aspiring deep tech founders should align financial modeling with R&D efforts to meet market needs. Utilizing advisors and mentors can strengthen market and financial understanding. Ensuring technical breakthroughs are financially viable is essential for market success.
#Fundraising #Startups #DeepTech #ConstructionTech #VentureCapital #Startups #VCs #CVCs #PhD #Startup #Founders #Mindset #Product #Business #industry #Materials
Disclaimer: This content is provided solely for educational and informational purposes and should not be interpreted as financial or legal advice. Given the complexity and potential impact of these terms, it is crucial to consult with an attorney. Legal expertise is invaluable in navigating these technical aspects and ensuring that the terms are in your best interests before finalizing any agreements.