OPENPediatrics

October is Sudden Infant Death Syndrome awareness month. Dr. Richard Goldstein, director of Robert’s Program on Sudden Unexplained Death in Pediatrics, provides an overview of Sudden Infant Death Syndrome (SIDS), including historical perspectives, definitions, current understanding of potential etiologies, and emerging research. Additionally, Dr. Goldstein offers practical tips for speaking with caregivers about SIDS. After this podcast, listeners will be able to: -Discuss the historical background of Sudden Infant Death Syndrome (SIDS) -Describe key terminology regarding SIDS and Sudden Unexplained Death in Pediatrics -Identify some of the proposed mechanisms related to SIDS -Discuss practical advice for speaking with families and caregivers Publication date: October 21, 2022. Articles referenced: • Goldstein RD, Kinney HC, Guttmacher AE. Only Halfway There with Sudden Infant Death Syndrome. N Engl J Med. 2022;386(20):1873-1875. (0:44) • MacDorman MF, Rosenberg HM. Trends in infant mortality by cause of death and other characteristics, 1960-88. Vital Health Stat 20. 1993;(20):1-57. (2:40) • Mitchell EA, Thach BT, Thompson JMD, Williams S, for the New Zealand Cot Death Study. Changing Infants' Sleep Position Increases Risk of Sudden Infant Death Syndrome. Arch Pediatr Adolesc Med. 1999;153(11):1136–1141. (2:48) • Haynes RL, Frelinger AL 3rd, Giles EK, et al. High serum serotonin in sudden infant death syndrome. Proc Natl Acad Sci U S A. 2017;114(29):7695-7700. (17:20) • Kinney HC, Haynes RL, Armstrong DD, et. al. Abnormalities of the Hippocampus in Sudden and Unexpected Death in Early Life. In: Duncan JR, Byard RW, eds. SIDS Sudden Infant and Early Childhood Death: The Past, the Present and the Future. University of Adelaide Press; 2018. (19:09) • Koh HY, Haghighi A, Keywan C, et al. Genetic Determinants of Sudden Unexpected Death in Pediatrics. Genet Med. 2022;24(4):839-850. (22:50) • Miller MB, Huang AY, Kim J, et al. Somatic genomic changes in single Alzheimer's disease neurons. Nature. 2022;604(7907):714-722. (30:45) • Warland J, O'Leary J, McCutcheon H, Williamson V. Parenting paradox: parenting after infant loss. Midwifery. 2011;27(5):e163-e169. (36:10) • Kinney HC, Richerson GB, Dymecki SM, Darnall RA, Nattie EE. The brainstem and serotonin in the sudden infant death syndrome. Annu Rev Pathol. 2009;4:517-550. (42:01) Additional references: • Recent article in "Inside Precision Medicine" quoting Dr. Goldstein https://bit.ly/3TzhG4j • Back to Sleep campaign: https://safetosleep.nichd.nih.gov/activities/campaign • https://www.childrenshospital.org/programs/roberts-program/clinician-resources • https://undiagnosed.hms.harvard.edu/ • https://www.broadinstitute.org/ • https://medicine.uiowa.edu/humangenetics/clinical-genetics/health-care-providers • https://www.genomeweb.com/informatics/microsoft-seattle-childrens-seek-genetic-markers-sids-through-whole-genome-sequencing#.Y1GOi-zMJqs • https://med.nyu.edu/departments-institutes/pediatrics/divisions/clinical-genetics/pediatric-undiagnosed-diseases-program • https://www.australiangenomics.org.au/research/the-australian-undiagnosed-diseases-network/ • https://ojrd.biomedcentral.com/articles/10.1186/s13023-021-02089-5 Citation: Goldstein R, Daniel D, Wolbrink T. Sudden Infant Death Syndrome. 10/22. Online Podcast. OPENPediatrics. https://youtu.be/pu-gnSCHDhw. OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access and thus at no expense to the user.

Dr. Christina VanderPluym, Co-Director of the Stroke and Cerebral Vascular Center at Boston Children’s Hospital, shares her expertise on anticoagulation management in pediatric patients using extracorporeal support devices. She discusses the complexities of managing heparin therapy, compares it with bivalirudin, and emphasizes the need for tailored approaches to minimize complications. Dr. VanderPluym also highlights the importance of monitoring hemostasis in children with ARDS and the challenges posed by evolving guidelines. It's a vital listen for anyone in pediatric care!

In this podcast, Erin Quinlan and Jennifer Schlebusch share their knowledge on mindfulness, and how it can be utilized as a stress reduction tool for nurses and their patients. They review different methods of mindfulness, including Reiki, and how to incorporate these tools into the hospital setting. Following this podcast, learners will be able to: 1:36 Define Mindfulness 2:12 List the types of mindfulness 12:55 Perform a breathing technique for stress reduction 14:43 Define Reiki and explain how it is used at the bedside Publication date: September 16, 2022 Articles Referenced: • Zaccaro A, Piarulli A, Laurino M, et al. How Breath-Control Can Change Your Life: A Systematic Review on Psycho-Physiological Correlates of Slow Breathing. Front Hum Neurosci. 2018;12:353. 7:15) • Jabs H, Rubik B. Detecting Subtle Energies with a Physical Sensor Array. Cosm. Hist. 2019;15(2), 171–192. (15:16) • Bat N. The effects of reiki on heart rate, blood pressure, body temperature, and stress levels: A pilot randomized, double-blinded, and placebo-controlled study. Complement Ther Clin Pract. 2021;43:101328. (20:51) Additional References: • Rubik B. The Biological Field with Beverly Rubik (video). 2017. https://www.newthinkingallowed.org/. • Kabat-Zinn, J. Full Catastrophe Living. Bantam Books; 2013. • Chiesa A, Calati R, Serretti A. Does mindfulness training improve cognitive abilities? A systematic review of neuropsychological findings. Clin Psychol Rev. 2011;31(3):449-464. • Demir Dogan M. The effect of reiki on pain: A meta-analysis [published correction appears in Complement Ther Clin Pract. 2021 Aug;44:101423]. Complement Ther Clin Pract. 2018;31:384-387. • Jain S, Mills PJ. Biofield therapies: helpful or full of hype? A best evidence synthesis [published correction appears in Int J Behav Med. 2011 Mar;18(1):79-82]. Int J Behav Med. 2010;17(1):1-16. • Lee MS, Pittler MH, Ernst E. Effects of reiki in clinical practice: a systematic review of randomised clinical trials. Int J Clin Pract. 2008;62(6):947-954. • Lipinski K, Van De Velde J. Reiki: Defining a Healing Practice for Nursing. Nurs Clin North Am. 2020;55(4):521-536. • Lipinski K, Van De Velde J. Reiki, Nursing, and Health Care. Nurs Clin North Am. 2020;55(4):505-519. • Miles P, True G. Reiki--review of a biofield therapy history, theory, practice, and research. Altern Ther Health Med. 2003;9(2):62-72. • Wetzel, WS. Reiki healing: a physiologic perspective. J Holistic Nursing.1989;7(1): 47-54. Citation: Quinlan E, Schlebusch J, DeGrazia M, Steadman J. Utilizing Mindfulness as a Stress Reduction Tool. 9/2022. Online Podcast. OPENPediatrics. https://youtu.be/D4mCptzkDcw. Please visit: www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu

In this podcast, the learner will learn how to approach patients with abdominal pain including recognition of important historical features, physical examination findings, and pertinent laboratory testing and imaging studies. Learning Objectives: - Recognize important historical features in patients with abdominal pain - Select physical examination maneuvers to identify specific causes of abdominal pain - Formulate a focused differential diagnosis based on patient age, pain localization and examination findings - Plan laboratory testing - Identify clinical scenarios where imaging studies are warranted for the evaluation of abdominal pain Citation: Stoeck P, Callas C, Fantasia K, Marques B, Wills K. Approach to Abdominal Pain. 09/2022. Online Video. OPENPediatrics. https://learn.openpediatrics.org/learn/course/internal/view/elearning/5265/approach-to-abdominal-pain. Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user.For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu

In this World Shared Practice Forum Podcast, Dr. Scott Watson, Associate Division Chief of the Division of Pediatric Critical Care Medicine at Seattle Children’s Hospital, discusses his article The Association of Acute Respiratory Failure in Early Childhood With Long Term Neurocognitive Outcomes, published in JAMA in March 2022. He reviews the methodology of the RESTORE trial of pediatric goal-directed sedation, and the approach the RESTORE group took in evaluating long term neurocognitive outcomes for study participants. Dr. Watson also shares his thoughts on the impact of these findings on current clinical practice. After listening to this podcast, learners will be able to: -Describe the association between acute respiratory failure and neurocognitive outcomes in children -Identify challenges in evaluating long term neurocognitive outcomes in children -Discuss future areas of interest in understanding the association between pediatric critical illness and neurocognitive outcomes Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu Articles Referenced: Watson RS, Beers SR, Asaro LA, et al. Association of Acute Respiratory Failure in Early Childhood With Long-term Neurocognitive Outcomes. JAMA. 2022;327(9):836-845. (1:07) Curley MA, Wypij D, Watson RS, et al. Protocolized sedation vs usual care in pediatric patients mechanically ventilated for acute respiratory failure: a randomized clinical trial. JAMA. 2015;313(4):379-389. (4:05) Publication date: July 22, 2022 Citation: Watson S, Daniel D, Burns JP. The Association of Acute Respiratory Failure in Early Childhood With Long Term Neurocognitive Outcomes. 07/2022. Online Podcast. OPENPediatrics. https://youtu.be/ODROLJ7HHes

In this World Shared Practice Forum podcast, Dr. Akash Deep, Director of the Pediatric Intensive Care Unit, Staff Governor, and Professor in Pediatric Critical Care at King’s College Hospital, discusses his recent publication on non-transplant options in pediatric acute liver failure. He describes important considerations for the management of acute liver failure and commonly associated toxicities, and offers insights into the paradigm shift currently evolving in the field and what we can expect in the trends of future treatment pathways. Upon listening to this presentation, learners should be able to: - Apply strategies for management of acutely ill children with acute liver failure - Describe various forms of toxicity commonly associated with acute liver failure Publication date: June 28, 2022. Articles Referenced: • Deep A, Nagakawa S, Tissieres P. Non-transplant options in paediatric acute liver failure-what is new?. Intensive Care Med. 2022;48(1):114-117. (00:49) • Habib M, Roberts LN, Patel RK, Wendon J, Bernal W, Arya R. Evidence of rebalanced coagulation in acute liver injury and acute liver failure as measured by thrombin generation. Liver Int. 2014;34(5):672-678. (7:03) • Slack AJ, Auzinger G, Willars C, et al. Ammonia clearance with haemofiltration in adults with liver disease. Liver Int. 2014;34(1):42-48. (13:27) • Hunt A, Tasker RC, Deep A. Neurocritical care monitoring of encephalopathic children with acute liver failure: A systematic review. Pediatr Transplant. 2019;23(7):e13556. (17:39) • Kochanek PM, Adelson PD, Rosario BL, et al. Comparison of Intracranial Pressure Measurements Before and After Hypertonic Saline or Mannitol Treatment in Children With Severe Traumatic Brain Injury. JAMA Netw Open. 2022;5(3):e220891. (19:51) Citation: Deep A, Daniel D, Burns JP. Non-transplant Options in Pediatric Acute Liver Failure. 6/2022. Online Podcast. OPENPediatrics. https://youtu.be/iSvZ26drzy0. Please visit: www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children's Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu Please note: OPENPediatrics does not support nor control any related videos in the sidebar, these are placed by Youtube. We apologize for any inconvenience this may cause.

In this new Nursing World Shared Practice Forum podcast, Mr. Greg Durkin reviews what it means to find joy in the workplace. He explains his exploration of joy and happiness, reviews how each is defined in popular culture, and how they are relevant to the nursing profession. Following this podcast, learners will be able to: - Define joy, professional joy, and happiness - Explain how you can find professional joy - Identify signs indicating that professional joy is lacking in your career Publish date: June 17, 2022. Citation: Durkin G, DeGrazia M. Finding and Defining Professional Joy. 06/2022. Online Podcast. OPENPediatrics. https://youtu.be/SvtJGqgMUzA. Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu

This podcast discusses how to distinguish among various types of stress, how stress manifests in the pediatric population, as well as suggesting strategies for families and physicians to implement in order to foster resilience through stressful aspects of life. Initial publication date: June 10, 2022 Citation: Coughlin C*, O’Meara D*, Ngo A, Chase B, Blackburn K. Pediatric Behavioral-Mental Health: Cultivating Resilience. 6/2022. Online Video. OPENPediatrics. https://soundcloud.com/openpediatrics/cultivating-resilience-by-brenna-chase-for-openpediatrics *These authors contributed equally to this work Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open access-and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu

In this World Shared Practice Forum podcast, Dr. Ericka Fink shares some of the​ epidemiologic insights produced by the PANGEA ​​pediatric neurocritical care global research network. Dr. Fink also shares her personal path as a researcher in pediatric neurocritical care, sharing some lessons learned and highlighting many of the mentors and organizations who have supported her along the way. Upon listening to this podcast, learners will be able to: - Describe the methodology and epidemiologic findings of the PANGEA Pediatric Neurocritical Care Research Program - Identify potential challenges in conducting medical research in resource-limited settings - List promising directions of research in the field of pediatric neurocritical care Publication date: May 23, 2022. Citation: Fink E, Daniel D, Wolbrink TA. Prevalence of Acute Critical Neurological Disease in Children. 05/2022. Online Podcast. OPENPediatrics. https://youtu.be/08cB83n4HpE. Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu

This podcast discusses pediatric depression and its prevalence in children and adolescents. The authors look into the guidelines in place for screening for and diagnosing depression and they also discuss various antidepressants, along with their side effects. After listening to this presentation, learners should be able to: - Describe the prevalence of pediatric depression in children and adolescents - Apply the American Academy of Child & Adolescent Psychiatry (or AACAP) guidelines, the American Academy of Pediatrics (or AAP) guidelines and DSM-5 criteria to screen for and diagnose patients with depression - Initiate, titrate, and discontinue antidepressants for unipolar pediatric depression - Describe the common and serious adverse effects of antidepressants Publication date: May 5, 2022. Citation: Ivanova M*, Chen P*, Chase B, Moye B, Wills K, Blackburn K., Pediatric Behavioral-Mental Health: Depression. 5/2022. Online Video. OPENPediatrics. https://learn.openpediatrics.org/learn/course/internal/view/elearning/5230/pediatric-behavioral-mental-health-depression. *These authors contributed equally to this work Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access and thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu