On the agenda for the final programme of the current series is meetings. Virtual or in person, it's difficult to avoid a work meeting. So how do you ensure a good meeting? What should their purpose be, how many people should attend, who should speak and when? Evan Davis and guests discuss. GUESTSDave Brittain, Business Development Director, Amazon Fashion EuropePhil Jones, MD Brother UKDr. Sarah Woolley, Senior Research Fellow, Warwick Business School CLIPS Series 3 Episode 3 W1AWriter: John Morton Rob Mayhew Brother Meeting Manifesto Writer: Rob Mayhew PRODUCTION TEAMProducer: Julie Ball Editor: China Collins Sound: Rod Farquhar and James Beard Production Co-ordinator: Gemma Ashman

The podcast discusses the creation and pricing of blockbuster drugs, focusing on recent examples such as Wegovy and Ozempic. It explores the challenges in determining the reasonable price for new medicines. Guests include Sir Patrick Vallance, Ruth McKernan, David Brown, and Natasha Loder. The chapters cover topics like the development of HIV drugs, the story behind Viagra, AI and data analysis in drug development, and the progression of treatments for rare diseases.

Long distance train travel and sleeper services are experiencing a resurgence in Europe. The concept of sleep services on trains is explored, highlighting affordability, convenience, and environmental benefits. The options and experiences of traveling on night trains are discussed, including the introduction of mini cabins for more privacy. Pricing and cost considerations of flights and trains are compared, discussing fuel consumption, accessibility issues, and the economics of train services.

Bad behaviour and big mistakes can destroy careers and even entire businesses if they're not addressed quickly, so why do some companies and their leaders try to downplay or even deny them?Evan Davis and guests discuss the culture of defensiveness and denial that exists in some organisations, from the private to the public and charity sectors. A former Oxfam worker describes how she was forced to blow the whistle on widespread sexual exploitation and abuse inside the charity, and the panel explores the ways in which leaders can tackle wrongdoing and encourage their teams to call it out.Evan is joined by:Helen Evans, former head of global safeguarding at Oxfam, now CEO of Cavernoma Alliance UK: John Higgins, researcher on workplace activism and author of “Speak Up: Say What Needs to Be Said and Hear What Needs to Be Heard”; Sarah Miller, CEO of Principia Advisory.PRODUCTION TEAM:Producer: Simon Tulett Editor: China Collins Sound: Graham Puddifoot and Rod Farquhar Production co-ordinators: Gemma Ashman and Sophie Hill(Picture: A businessman with his head in the sand. Credit: Getty Images)

Elon Musk’s decision to rename Twitter ‘X’ has been met with confusion, and in some cases even anger, but where does it rank amongst the best and worst rebrands?Evan Davis and guests discuss the complexity of changing a company or product name, logo and message, the reasons for doing it, and how to make it a success.These overhauls can be risky, though, and failure expensive – the panel discusses one the UK’s textbook rebranding disasters.Evan is joined by:Lee Rolston, chief growth officer at Jones Knowles Ritchie; Caroline Wiertz, professor of marketing at Bayes Business School (formerly Cass) – City, University of London; Amanda Mackenzie, former chief marketing and communications officer at Aviva; Keith Wells, founder and director of Brandwell.PRODUCTION TEAM:Producer: Simon Tulett Editor: China Collins Sound: Graham Puddifoot and Rod Farquhar Production co-ordinator: Gemma Ashman(Picture: The new ‘X’ logo displayed on a smartphone with the old Twitter logo in the background. Credit: Omar Marques/SOPA Images/LightRocket via Getty Images.)

Demis Hassabis, Co-founder of AI research lab DeepMind, discusses Google's answer to ChatGPT and AI's breakthroughs, but also its downsides, including potential human extinction. He explores his journey from chess player to AI creator and the transformative breakthroughs in driverless cars and protein structure prediction. The podcast also covers legal issues surrounding AI, DeepMind's unique innovation culture, and Google's use of AI in various products.

From plumbers to electricians, plasterers to builders, most of us need to hire a trader at some point. But what's it like to work in the industry, and how has it been affected by changes such as Brexit, the pandemic and inflation? How should you go about finding a trader who is trustworthy and will deliver quality work? In recent decades, going into a 'trade' has not been as strongly encouraged as to going to university, but tradespeople of all kinds are in short supply, so what is being done to encourage more young people to take up a trowel or pick up a drill? Evan Davis and guests discuss.CONTRIBUTORSChris Day - Electrician, Mayday Electrical Solutions Ltd.Kalece Okusanya - Decorator - Suave Property Care Will Davies - Co founder , Aspect Property Maintenance Tim Balcon - CEO, Construction Industry Training BoardPeter Gordon - ListenerPRODUCTION TEAMProducer: Julie Ball Editor: China Collins Sound: Tim Heffer and Graham Puddifoot Prod. Co-ordinator: Gemma Ashman

Many employers say they are desperate to get staff back into the office more often, but what's the best and fairest way to wean employees off remote working?As companies from tech to banking grapple with this issue, Evan Davis and guests discuss the productivity pros and cons, the impact on company culture and career progression, and the future of the office space itself. With many staff reluctant to give up the flexibility of remote working, is a hybrid model the answer to keeping them happy and how many office days each week should you go for? Plus, where do employees stand legally on return to the office requests, and what happens when workers simply refuse to comply?Evan is joined by:Kelly Beaver, CEO of Ipsos in the UK and Ireland; Stephen White, Chief Operating Officer of Santander UK; Ranjit Dhindsa, head of employment at Fieldfisher; and Nicholas Bloom, professor of economics, Stanford University.PRODUCTION TEAM:Producer: Simon Tulett Editor: China Collins Sound: Rod Farquhar Production co-ordinator: Gemma Ashman(Picture: A businessman staring out of the window of an empty conference room. Credit: Chris Ryan/Getty Images)

Is humour the most effective way to get your product noticed? If so, why does it seem that the use of comedy in advertising is in decline? Recent research by Kantar found that 90% of consumers were more likely to remember and purchase a brand if the advert made them smile. So why the downturn? Are multi-national brands looking for a one size fits all approach, or are brands frightened of offending potential customers? Evan Davis and guests discuss.PRESENTER: Evan Davis GUESTSRory Sutherland, VP, Ogilvy UKLucy Greeves, Author and Creative StrategistDom Dwight, Marketing Director, Taylors of Harrogate and Yorkshire TeaADVERT CLIP: Yorkshire Tea - Induction Training with Sean Bean Courtesy of Taylors of Harrogate, Yorkshire Tea Creative: Lucky Generals Advertising AgencyPRODUCTION TEAMProducer: Julie Ball Editor: China Collins Sound: Graham Puddifoot Production Co-ordinator: Brenda BrownThe Bottom Line is produced in partnership with The Open University

England’s water companies are under fire – there’s public anger over sewage spills and leaks, and now regulators and government ministers are worried some of them are drowning in too much debt. So what’s gone wrong, and who will pay the price of fixing the industry?On the face of it, running a water company seems like a licence to print money – there’s guaranteed revenue, and no competition – but there’s a lot of infrastructure to build and maintain, and strict targets that are getting even tougher and more expensive to hit as environmental concerns grow. Many of England’s water firms have taken on very high levels of debt, but have they used it to invest, or pay off their shareholders? And does the regulator, Ofwat, have questions to answer for strangling spending on improvements in a bid to keep customer prices low?Evan Davis is joined by:Nicola Shaw, CEO, Yorkshire Water; Sir Ian Byatt, Ofwat Director General from 1989 to 2000; Verity Mitchell, UK analyst at Global Water Intelligence.PRODUCTION TEAM:Producer: Simon Tulett Editor: China Collins Sound: Graham Puddifoot and Mike Woolley Production co-ordinator: Brenda BrownProduced in partnership with The Open University.