Neurology® Podcast

Neurologist Dr. Maureen Leehey discusses a trial on CBD/THC cannabis extract for Parkinson's patients, highlighting motor symptom improvements but no significant difference from the placebo group. The podcast explores the risks of THC concentrates in elderly patients and the potential placebo effect of using a previously illegal substance.

Dr. Sarah Louise Edwards and Dr. Zachary London discuss game-based learning in neuroscience education, exploring definitions of games, gamification, and Serious Games. They delve into the use of gamification in neurology, review literature on gaming in neuroscience, and outline the educational game design process.

Dr. Alison M. Pack, expert in neurodevelopment, discusses guidelines on antiseizure meds & folic acid impact on children born to PWECP. Topics include folic acid supplementation, risks of valproic acid, and recommendations on medication use during pregnancy.

Dr. Adam de Havenon discusses the burden of neurologic healthcare after COVID-19 vs influenza hospitalization. The podcast analyzes rates of neurologic diagnoses, healthcare utilization, and extensive medical data research. Findings show lower odds of receiving healthcare for neurologic conditions in COVID-19 patients compared to flu, despite lower readmission rates.

Dr. Rob de Bie discusses early vs. delayed start of Levodopa in Parkinson's disease, dosage management, disease progression, challenges in symptom assessment, accuracy in diagnosis, and gender-specific medication considerations based on study outcomes.

Dr. Alice Tang discusses the association between immune status and herpes simplex virus encephalitis. Topics include risk factors for HSV encephalitis, traditional vascular risk factors, impact of comorbidities on immunocompromised patients, and the importance of prompt identification and treatment in neurological emergencies.

Drs. Jacqueline French and Nora Jandhyala discuss challenges in identifying non-motor seizures in adolescents with focal epilepsy, highlighting missed diagnostic opportunities and the importance of early intervention. They explore risks of missed diagnoses, injuries, and lack of specialist referrals, emphasizing the need for improved emergency department protocols. The significance of non-motor symptoms in first-time seizures is also emphasized, advocating for timely diagnosis and management to prevent tragic consequences.

The May 2024 replay features four episodes on neuro-oncology for brain cancer awareness month. The episode begins with Dr. Philipp Karschnia discussing the assessment of whether MTHFR polymorphisms affect the risk for leukoencephalopathy. The episode continues with Dr. Ingo Mellinghoff discussing new treatment opinions for isocitrate dehydrogenase (IDH)–mutant grade 2 gliomas. The third interview leads into a conversation with Dr. Linda Liau on the study of vaccine-based therapy for GBM. The episode concludes with Dr. Teddy Totimeh talking about brain tumor programs in Asia and Africa. Podcast Links: MTHFR Polymorphisms and Leukoencephalopathy Risk in CNS Lymphoma Patients   New Treatment for IDH mt Gliomas  Study of Vaccine-Based Therapy for GBM Brain Tumor Programs in Asia and Africa  Article Links: https://doi.org/10.1212/WNL.0000000000207670  https://www.nejm.org/doi/full/10.1056/NEJMoa2304194 https://jamanetwork.com/journals/jamaoncology/fullarticle/2798847 https://doi.org/10.1016/j.wneu.2023.04.067 Disclosures can be found at Neurology.org.

Dr. Justin Abbatemarco talks with Dr. Bob Fox about the relationship between serum neurofilament light chain (sNfL) levels and radiologic multiple sclerosis disease activity. Read the related article in Neurology. Disclosures can be found at Neurology.org.

Dr. Ellen Iacobaeus discusses late-onset MS in Swedish patients, highlighting differences with adult-onset MS like higher disability levels and less inflammation. She explores challenges in therapy, prescribing patterns, and managing late-onset MS patients, emphasizing the need for tailored treatment and vigilant monitoring.