The Fellow on Call: The Heme/Onc Podcast

We are taking a small pause from our breast cancer series to discuss an important topic that is so critical to understand for clinical practice, no matter what discipline of medicine you are in: the fundamentals of transfusion medicine. This topic often shows up quite frequently on board exams, as well. In this episode, we talk about terms such as “type and screen” and more. Content: - What is a "type and screen"?- What does this process entail? - What is the difference between this and crossmatching? - When do we see discrepancies in the antibody screen? ** Want to review the show notes for this episode and others? Check out our website: https://www.thefellowoncall.com/our-episodesLove what you hear? Tell a friend and leave a review on our podcast streaming platforms!Twitter: @TheFellowOnCallInstagram: @TheFellowOnCallListen in on: Apple Podcast, Spotify, and Google Podcast

Surprise! The teams at Two Onc Docs and The Fellow on Call are teaming up for his special series! Each episode will focus on a single abstract, poster, or oral presentation from ASCO 2023, and will feature a quick review of any guidelines and management pointers relevant to the disease state under study, followed by an overview of the study design and findings, and finally a discussion of the implications of the research on clinical practice.We expect to release episodes on June 12, 14, 19, 21, and 26. Episodes will be released alternating between our two podcasts, so make sure you’re subscribed to both!Follow Two Onc Docs on Twitter: www.twitter.com/twooncdocsSubscribe to Two Onc Docs on Apple Podcasts: https://podcasts.apple.com/us/podcast/two-onc-docs/id1616541733 Follow The Fellow on Call on Twitter: www.twitter.com/thefellowoncall Subscribe to The Fellow on Call on Apple Podcasts: https://podcasts.apple.com/us/podcast/the-fellow-on-call-the-heme-onc-podcast/id1602921628 Subscribe to The Fellow on Call on Spotify: https://open.spotify.com/show/3LFKY3jlU2T0MpvKwkvMvl?si=acca1fa9413a4f60&nd=1 Subscribe to The Fellow on Call on Google Podcasts: https://podcasts.google.com/search/the%20fellow%20on%20call

The hosts dive deep into the management of early stage ER+/HER2- breast cancer. They discuss who should receive chemotherapy and the relevance of gene expression assays like Oncotype and MammaPrint. Key trial results shed light on treatment distinctions based on menopausal and nodal status. The conversation also covers selecting appropriate chemotherapy regimens, the importance of survivorship care, and introduces targeted adjuvant therapies like abemaciclib for high-risk patients. It's a goldmine of insights for those navigating breast cancer treatment.

Dive into the intricacies of early-stage ER+/HER2- breast cancer as experts discuss essential factors like tumor size and grade. The role of chemotherapy is examined, along with varying treatment regimens and their trade-offs. Key insights into endocrine therapy highlight how menopausal status affects treatment choices. Discover the implications of ovarian suppression in high-risk cases, making this a must-listen for anyone interested in advanced cancer care strategies.

Join Dr. Danielle Roman, an Oncology Clinical Pharmacy Specialist, as she dives into the complexities of breast cancer pharmacology. She covers critical topics like the impact of different anti-estrogen therapies and their side effects. The discussion includes insights on regimens for ER+, HER2+, and triple-negative cases, along with key trial highlights. Dr. Roman also emphasizes supportive care strategies, offering practical guidance for clinicians to better counsel their patients on these treatments.

Dr. Carla Fisher, an Associate Professor and Medical Director of Breast Surgical Oncology, discusses vital topics in breast cancer management. She explains the criteria for breast conservation surgery and the role of imaging, such as when to order an MRI. Dr. Fisher also covers the timing of surgical interventions post-neoadjuvant therapy and the significance of sentinel lymph node biopsies. Additionally, she highlights the complexities of breast reconstruction and when prophylactic mastectomy is indicated. Valuable insights for patients and healthcare professionals alike!

Dive into the complex vocabulary surrounding breast cancer. Unravel important terms like ER/PR and HER2 that shape diagnosis and treatment. Learn about the significance of different tumor types and grading systems. Explore molecular subtypes and genomic assays that guide personalized care. Get the lowdown on surgical terminology and TNM staging mnemonics. Plus, discover essential endpoints in clinical trials. This insightful journey will empower you to better understand and communicate the nuances of breast cancer.

In this engaging discussion, Dr. Ryan Miller, a radiation oncology resident at Thomas Jefferson University Hospital, dives into the essential role of radiation therapy in breast cancer treatment. He explains the significance of radiation boosts and regional nodal irradiation, clarifying when they are needed. Dr. Miller also addresses the interplay between concurrent systemic therapies and radiation. Plus, he highlights scenarios for omitting radiation and the specifics of treating DCIS, making this a valuable listen for anyone interested in oncology insights.

In this engaging discussion, Dr. Yasha Gupta, a breast imaging fellow at Memorial Sloan Kettering, dives into the essentials of breast cancer imaging. She clarifies the differences between screening and diagnostic mammograms, unpacking the significance of BI-RADS categories in biopsy decisions. Dr. Gupta elaborates on the use of marker clips in procedures and the advantages of tomosynthesis for improved lesion characterization. Listeners gain insights into assessing axillary lymph nodes and the critical collaboration needed with breast radiologists for optimal patient care.

Dive into the complexities of leukocytosis with insights on initial triage steps and essential history-taking. Learn about the physiology behind leukocyte behaviors and the importance of cell differentiation pathways. Discover the practical approaches to various types of white blood cell increases, from neutrophilia to lymphocytosis. Key laboratory tests and screening techniques are highlighted, along with expert tips on when to refer cases to hematology. It's an informative resource for clinicians navigating challenging inpatient scenarios!