
The Dr. Gabrielle Lyon Show
The Dr. Gabrielle Lyon Show promotes a healthy world, and in order to have a healthy world, we must have transparent conversations. This show is dedicated to such conversations as the listener; your education, understanding, strength, and health are the primary focus. The goal of this show is to provide you with a framework for navigating the health and wellness space and, most importantly, being the champion of your own life. Guests include highly trustworthy professionals that bring both the art and science of wellness aspects that are both physical and mental. Dr. Gabrielle Lyon is a Washington University fellowship-trained physician who serves the innovators, mavericks, and leaders in their fields, as well as working closely with the Special Operations Military. She is the founder of the Institute of Muscle-Centric Medicine® and serves patients worldwide.
Latest episodes

16 snips
Jul 15, 2025 • 1h 53min
Why Protein Isn’t Always Enough: Anabolic Resistance, Obesity, and Protein Efficiency | Dr. Nick Burd
In this engaging discussion, Dr. Nick Burd, a leading muscle-metabolism scientist and professor at the University of Illinois, reveals why protein intake isn’t the whole story for muscle health. He explores anabolic resistance, particularly in older adults and those with obesity, highlighting how age and body composition affect muscle protein synthesis. Dr. Burd discusses the inefficiencies of plant-based proteins and the significance of combining exercise and nutrition strategies. Tune in to learn how to optimize your protein efficiency and promote better muscle health!

7 snips
Jul 8, 2025 • 1h 43min
How to Prevent Heart Disease with Mitochondria, Muscle, and the Endothelial Glycocalyx | Dr. Michael Twyman
Dr. Michael Twyman, a board-certified cardiologist and founder of Apollo Cardiology, shares his expertise on heart disease prevention. He discusses the alarming prevalence of silent heart attacks and introduces the importance of nitric oxide and muscle mass in promoting cardiovascular health. Twyman highlights innovative diagnostics and debunks common myths around cardiovascular risk. Listeners learn actionable steps and lifestyle choices for optimizing heart health, including the roles of supplements and advanced imaging techniques.

63 snips
Jul 1, 2025 • 1h 23min
Stronger: The Untold Story of Muscle, Strength, and Human Potential | Michael Joseph Gross
Join journalist Michael Joseph Gross, author of "Stronger: The Untold Story of Muscle in Our Lives," as he uncovers the significance of muscle throughout history and its vital role in health today. He debunks myths about muscle and aging, emphasizing that muscle mass is crucial for longevity and overall well-being. Gross also delves into women's empowerment in strength training, the connection between mental health and physical prowess, and how society can better appreciate the essential nature of muscle in our lives.

36 snips
Jun 24, 2025 • 1h 11min
Food & Metabolomics: How Your Diet—Starting in Childhood—Shapes Your Brain | Dr. Alexis Wood
Dr. Alexis Wood, an Associate Professor of Pediatrics–Nutrition at Baylor College of Medicine, dives into how childhood nutrition shapes lifelong brain health. She discusses the often-overlooked connections between diet, genetics, and cognitive development. Topics include the myths surrounding ADHD and diet, the benefits of the Mediterranean diet, and the importance of personalized nutrition through metabolomics. Listeners gain insight into how dietary choices, especially in early life, can impact cognitive outcomes and health.

32 snips
Jun 17, 2025 • 1h 49min
Are Red Meat Warnings Based on Flawed Science? Dr. David Klurfeld on Nutrition Myths and Industry Bias
Dr. David Klurfeld, a former USDA nutrition leader and chair at Wayne State University, dives into the controversies of red meat consumption and nutrition science. He questions the 2015 IARC classification of red meat as a carcinogen, revealing its weak evidence base and the biases in nutritional studies. Klurfeld highlights the challenges of observational research and underscores the importance of distinguishing correlation from causation. His insights encourage critical thinking on dietary guidelines and the real impacts of red meat on health.

22 snips
Jun 10, 2025 • 1h 47min
Why Men’s Fertility Is Declining: The Truth About Testosterone | Dr. Larry Lipshultz
Dr. Larry Lipshultz, a leading expert in men's reproductive health, dives into the alarming decline of male fertility, revealing a staggering 50% drop since the 1980s. He dispels myths about testosterone therapy and prostate cancer while discussing the environmental factors affecting men's health. The conversation uncovers innovative treatments for restoring fertility and emphasizes the importance of personalized care. Lipshultz also highlights the risks and benefits of anabolic agents, advocating for informed and safer approaches to testosterone therapy.

223 snips
Jun 3, 2025 • 1h 16min
How to Train Your Mind: Ancient Wisdom, Modern Science, and the Mindset of Excellence | Brian Johnson
In this engaging discussion, Brian Johnson, the Founder of Heroic and a modern philosopher, shares insights on behavior change and the power of ancient wisdom, particularly stoicism. He explains why motivation often falters without structure and how anti-fragility can transform challenges into opportunities. Brian connects physical training to building character and emphasizes that personal responsibility is crucial for excellence. Listeners will find practical wisdom for bridging the gap between potential and action, ultimately fostering resilience and self-improvement.

116 snips
May 27, 2025 • 1h 59min
Understanding Heart Rate Variability: Improving Your Health & Performance | Joel Jamieson
Joel Jamieson, a renowned coach with over 20 years in recovery training, discusses the impact of heart rate variability (HRV) on health and performance. He reveals why elite athletes recover swiftly and the benefits of zone 2 training for longevity. Jamieson highlights the role of lifestyle stress over workouts, shares insights from his work with Olympians and NFL players, and emphasizes the importance of monitoring HRV trends rather than daily fluctuations. His practical advice reshapes the way listeners approach training and recovery.

37 snips
May 20, 2025 • 1h 11min
Why Do Most Diets Fail? The Science of Nutrient Deficiencies | Ty Beal PhD
In this engaging discussion, Dr. Ty Beal, a Senior Technical Specialist at GAIN and a global nutrition researcher, highlights the hidden epidemic of micronutrient deficiencies affecting billions worldwide. He examines why 3 billion people can’t afford healthy diets and the impact of ultra-processed foods displacing nutrient-rich options. Dr. Beal emphasizes the critical need for dietary diversity, fortification, and the overlooked risks of plant-based diets. This chat uncovers the complexities of nutrition, particularly for women and children, and the urgent need for reform in food systems.

17 snips
May 13, 2025 • 1h 24min
Women’s Training & The Menstrual Cycle: What the Science Actually Says | Lauren Colenso-Semple, PhD
In this engaging conversation, Dr. Lauren Colenso-Semple, a muscle physiology researcher with a PhD in integrative physiology, challenges common myths about women’s training and physiology. She discusses whether workouts should align with the menstrual cycle, the real effects of hormonal birth control on muscle growth, and how menopause impacts body composition. Highlighting the importance of consistency over hormonal fluctuations, Lauren emphasizes that every woman can train effectively without being limited by her physiology.