
The Dr. Gabrielle Lyon Show
The Dr. Gabrielle Lyon Show promotes a healthy world, and in order to have a healthy world, we must have transparent conversations. This show is dedicated to such conversations as the listener; your education, understanding, strength, and health are the primary focus. The goal of this show is to provide you with a framework for navigating the health and wellness space and, most importantly, being the champion of your own life. Guests include highly trustworthy professionals that bring both the art and science of wellness aspects that are both physical and mental. Dr. Gabrielle Lyon is a Washington University fellowship-trained physician who serves the innovators, mavericks, and leaders in their fields, as well as working closely with the Special Operations Military. She is the founder of the Institute of Muscle-Centric Medicine® and serves patients worldwide.
Latest episodes

10 snips
Jun 24, 2025 • 1h 11min
Food & Metabolomics: How Your Diet—Starting in Childhood—Shapes Your Brain | Dr. Alexis Wood
Dr. Alexis Wood, an Associate Professor of Pediatrics–Nutrition at Baylor College of Medicine, dives into how childhood nutrition shapes lifelong brain health. She discusses the often-overlooked connections between diet, genetics, and cognitive development. Topics include the myths surrounding ADHD and diet, the benefits of the Mediterranean diet, and the importance of personalized nutrition through metabolomics. Listeners gain insight into how dietary choices, especially in early life, can impact cognitive outcomes and health.

26 snips
Jun 17, 2025 • 1h 49min
Are Red Meat Warnings Based on Flawed Science? Dr. David Klurfeld on Nutrition Myths and Industry Bias
Dr. David Klurfeld, a former USDA nutrition leader and chair at Wayne State University, dives into the controversies of red meat consumption and nutrition science. He questions the 2015 IARC classification of red meat as a carcinogen, revealing its weak evidence base and the biases in nutritional studies. Klurfeld highlights the challenges of observational research and underscores the importance of distinguishing correlation from causation. His insights encourage critical thinking on dietary guidelines and the real impacts of red meat on health.

22 snips
Jun 10, 2025 • 1h 47min
Why Men’s Fertility Is Declining: The Truth About Testosterone | Dr. Larry Lipshultz
Dr. Larry Lipshultz, a leading expert in men's reproductive health, dives into the alarming decline of male fertility, revealing a staggering 50% drop since the 1980s. He dispels myths about testosterone therapy and prostate cancer while discussing the environmental factors affecting men's health. The conversation uncovers innovative treatments for restoring fertility and emphasizes the importance of personalized care. Lipshultz also highlights the risks and benefits of anabolic agents, advocating for informed and safer approaches to testosterone therapy.

222 snips
Jun 3, 2025 • 1h 16min
How to Train Your Mind: Ancient Wisdom, Modern Science, and the Mindset of Excellence | Brian Johnson
In this engaging discussion, Brian Johnson, the Founder of Heroic and a modern philosopher, shares insights on behavior change and the power of ancient wisdom, particularly stoicism. He explains why motivation often falters without structure and how anti-fragility can transform challenges into opportunities. Brian connects physical training to building character and emphasizes that personal responsibility is crucial for excellence. Listeners will find practical wisdom for bridging the gap between potential and action, ultimately fostering resilience and self-improvement.

116 snips
May 27, 2025 • 1h 59min
Understanding Heart Rate Variability: Improving Your Health & Performance | Joel Jamieson
Joel Jamieson, a renowned coach with over 20 years in recovery training, discusses the impact of heart rate variability (HRV) on health and performance. He reveals why elite athletes recover swiftly and the benefits of zone 2 training for longevity. Jamieson highlights the role of lifestyle stress over workouts, shares insights from his work with Olympians and NFL players, and emphasizes the importance of monitoring HRV trends rather than daily fluctuations. His practical advice reshapes the way listeners approach training and recovery.

37 snips
May 20, 2025 • 1h 11min
Why Do Most Diets Fail? The Science of Nutrient Deficiencies | Ty Beal PhD
In this engaging discussion, Dr. Ty Beal, a Senior Technical Specialist at GAIN and a global nutrition researcher, highlights the hidden epidemic of micronutrient deficiencies affecting billions worldwide. He examines why 3 billion people can’t afford healthy diets and the impact of ultra-processed foods displacing nutrient-rich options. Dr. Beal emphasizes the critical need for dietary diversity, fortification, and the overlooked risks of plant-based diets. This chat uncovers the complexities of nutrition, particularly for women and children, and the urgent need for reform in food systems.

17 snips
May 13, 2025 • 1h 24min
Women’s Training & The Menstrual Cycle: What the Science Actually Says | Lauren Colenso-Semple, PhD
In this engaging conversation, Dr. Lauren Colenso-Semple, a muscle physiology researcher with a PhD in integrative physiology, challenges common myths about women’s training and physiology. She discusses whether workouts should align with the menstrual cycle, the real effects of hormonal birth control on muscle growth, and how menopause impacts body composition. Highlighting the importance of consistency over hormonal fluctuations, Lauren emphasizes that every woman can train effectively without being limited by her physiology.

59 snips
May 6, 2025 • 1h 25min
The Truth About Women’s Metabolism, Muscle & Fat Loss at Every Age | Abbie Smith-Ryan, PhD
Dr. Abbie Smith-Ryan, a leading expert in exercise physiology and sports nutrition, joins the discussion to reveal how women can effectively navigate changes during perimenopause and postmenopause. She uncovers the benefits of high-intensity interval training (HIIT) for improving fitness and body composition. Topics include the impact of nutrition timing on recovery, the misconceptions surrounding weightlifting, and the importance of individualized training. Abbie also addresses hydration, under-fueling, and the unique metabolic challenges women face, all backed by research.

68 snips
Apr 29, 2025 • 1h 42min
The Truth About Sweeteners, Seed Oils, and Building Real Strength | Nick Barringer, PhD
In this engaging discussion, Dr. Nick Barringer, a Nutritional Physiologist and veteran Army Ranger, sheds light on controversial nutrition topics. He tackles the safety of artificial sweeteners like sucralose and aspartame, and clarifies myths about seed oils. Barringer shares insights on the underrated benefits of creatine for both muscle and cognitive function. He also emphasizes personalized nutrition strategies for those over 40, hydration tips for athletes, and the importance of balanced omega fatty acids for overall wellness.

17 snips
Apr 22, 2025 • 1h 15min
Is Ozempic Actually Safe? CEO of Major Pharmacy Speaks Out | Shaun Noorian, CEO
In a riveting discussion, Shaun Noorian, engineer and CEO of Empower Pharmacy, dives into the world of compounded GLP-1 medications. He breaks down the legalities and safety concerns surrounding these therapies amid rising pressures from Big Pharma. Shaun highlights why Americans face exorbitant drug prices, sometimes 10 times higher than Europeans, and sheds light on the urgent need for patient advocacy. He passionately advocates for the role of compounding pharmacies in making life-saving medications accessible and affordable to all.