

Longevity Optimization with Kayla Barnes-Lentz
Kayla Barnes-Lentz
Maximizing Human Health and Performance. We discuss: optimal health, nutrition, high-performance, cognitive excellence, biohacking, longevity and more with top experts around the world. Hosted by Kayla Barnes-Lentz.
Episodes
Mentioned books

Feb 13, 2025 • 1h 2min
AI: How it Works + AI in Medicine with Harper Carroll
Today I'm speaking with @HarperCarrollAI an AI and ML software engineer, on the Longevity Optimization Podcast. In this episode, we explore the fascinating intersection of artificial intelligence and health optimization. Harper shares insights into the concept of AI as the ultimate polymath, detailing her journey into the field and the transformative potential of AI in revolutionizing health diagnostics and treatments, particularly in cancer care. The conversation delves into the implications of AI in personalized medicine and how technology can shape the future of health optimization.Harper Carroll is an AI/ML engineer, advisor and educator focused on making AI concepts accessible. With almost a decade of formal experience in AI, she holds two Computer Science degrees from Stanford University specializing in AI, worked at Facebook/Meta on News Feed Ranking, Integrity Intelligence, and AR, and then was Founding Engineer and then Head of AI/ML at a startup acquired by NVIDIA. Her background combines technical expertise with teaching experience, including as a TA for advanced CS and AI courses at Stanford, including a PhD-level core AI course. Her model fine-tuning guides became the most popular fine-tuning guides on Google. In just one (1) year of teaching AI online, she has garnered 0.5M followers.Polymath book Harper references: Genesis: Artificial Intelligence, Hope, and the Human Spirit: https://www.amazon.com/Genesis-Artificial-Intelligence-Human-Spirit/dp/0316581291Follow Harper on IG: https://www.instagram.com/harpercarrollai/Follow Her on YouTube: https://www.youtube.com/@HarperCarrollAIFollow Her on X: https://x.com/HarperSCarrollVisit Her Website: https://www.harpercarrollai.comTimestamps00:00 Introduction to AI and Longevity05:08 The Polymath Concept in AI09:58 Harper's Journey into AI14:47 Understanding AI: Definitions and Applications19:56 AI in Health: Opportunities and Concerns25:00 AI's Role in Cancer Treatment and Diagnostics30:10 Future of AI in Personalized Medicine32:23 Innovative Approaches to Women's Health35:11 The Role of AI in Health Optimization36:51 Empathy and Virtual Reality Experiences41:05 AI's Impact on Creativity and Accessibility43:59 AI as a Personal Assistant in Daily Life48:54 Understanding AI Hallucinations and Their Implications53:28 The Environmental Impact of AI and Future Solutions

Feb 6, 2025 • 1h 1min
Functional Mushrooms For Health
Today I'm speaking with Julian Mitchell from Life Cykel. In this episode, we delve into the fascinating world of functional mushrooms, particularly focusing on Lion's Mane, Reishi, and Cordyceps. Julian shares insights into the origins of Life Cykel and the extensive research supporting the benefits of these mushrooms for cognitive health, sleep optimization, and gut health. The conversation emphasizes the importance of biohacking and how mushrooms can enhance overall well-being and longevity.
Julian Mitchell is a passionate advocate for the health benefits of functional mushrooms and the co-founder of Life Cykel, a company dedicated to harnessing the power of these natural wonders. With a background in health and wellness, Julian has dedicated his career to exploring the intersection of traditional medicine and modern science. He highlights the significance of gut health and its profound impact on overall well-being, discussing the roles of mushrooms like Turkey Tail and Shiitake in promoting health. The conversation also covers the importance of gut testing, the historical use of mushrooms in traditional medicine, and advancements in extraction methods that improve bioavailability. Julian emphasizes sustainable cultivation practices and rigorous quality control measures to ensure product integrity, concluding with a focus on the benefits of specific mushrooms and the importance of choosing high-quality products for optimal health.
Shop Life Cykle here and save with code Kayla20: https://us.lifecykel.com/collections/all
Follow Lifecykel on Instagram and TikTok!
Timestamps
00:00 Introduction to Functional Mushrooms and Life Cykel
01:30 The Journey of Starting a Mushroom Company
04:08 Research and Benefits of Lion's Mane Mushroom
09:02 Lion's Mane and Its Impact on Sleep and Memory
10:40 Exploring Other Mushrooms: Reishi and Cordyceps
19:35 The Role of Turkey Tail and Gut Health
28:04 The Importance of Gut Health
29:19 Understanding Gut Testing and Probiotics
30:21 Root Causes of Health Issues
31:44 Exploring Turkey Tail Mushroom
33:07 Historical Use of Mushrooms in Medicine
35:26 Advancements in Mushroom Extraction
39:03 Sustainable Mushroom Cultivation
42:00 Quality Control in Mushroom Products
51:34 Benefits of Shiitake Mushroom
55:29 Bioavailability of Mushroom Products
59:22 Choosing Quality Mushroom Products

Jan 30, 2025 • 1h 37min
Live Longer and Healthier with Dr. Alexander Paziotopoulos, MD
Today I'm speaking with Dr. Paziotopoulos on the Longevity Optimization Podcast. In this episode, we explore his unique journey into the field of medicine and longevity, focusing on the integration of AI in health monitoring and the innovative concept of medical maintenance engineering. The conversation delves into the importance of imaging, the role of supplements, and the critical significance of compliance in health programs. Dr. Paziotopoulos highlights key compounds for longevity, emphasizing the essential role of vitamin D in overall health and its importance in cancer prevention.
Dr. Paziotopoulos is a distinguished physician and researcher with a deep commitment to advancing the field of longevity and personalized medicine. With a background in both traditional medicine and cutting-edge technology, he has become a thought leader in the integration of artificial intelligence into health monitoring systems. His expertise encompasses a wide range of health topics, including the development of innovative health protocols and the exploration of novel compounds that promote longevity. Dr. Paziotopoulos is particularly passionate about the role of vitamin D in health, as well as the importance of water filtration and gut health. His forward-thinking approach emphasizes the need for data-driven solutions in healthcare, making him a pivotal figure in the future of age-reversal medicine and functional health.
Follow him on Instagram : https://www.instagram.com/alexpazio/
Timestamps
02:57 The Journey to Medicine and Longevity
06:11 Medical Maintenance Engineering: A New Approach
09:05 Imaging and AI in Health Monitoring
11:59 The Role of Supplements in Longevity
18:03 The Importance of Compliance in Health Programs
21:01 Exploring Key Compounds for Longevity
23:59 The Benefits of Natural Foods vs. Supplements
26:57 Vitamin D: The Essential Hormone for Health
31:04 Vitamin D and Cancer Prevention
32:41 Exploring Methylene Blue
34:32 The Importance of Water Filtration
40:53 Patient Management and Protocol Development
52:33 Age-Reversal Medicine and Future Therapies
01:01:04 The Future of Medical Maintenance Engineering
01:03:43 The Future of Data-Driven Medicine
01:12:27 Understanding Omics and Personalized Health
01:19:24 AI's Role in Longevity and Health Optimization
01:26:40 Innovations in Cancer Detection and Treatment

Jan 23, 2025 • 1h 6min
Good Stress with Jeff Krasno
Today I'm speaking with Jeff Krasno on the Longevity Optimization Podcast. In this episode, we explore his transformative journey from the music industry to the wellness space, where he shares the profound impact of 9/11 on his life, the founding of Wanderlust, and a personal health crisis that ignited his passion for metabolic health and the concept of good stress. The conversation also touches on the launch of a female health community and the challenges of modern living, emphasizing the need to reconnect with our ancestral roots for better health.Jeff Krasno is a visionary entrepreneur and wellness advocate, best known for creating the Wanderlust festival, which celebrates mindful living and holistic health. His experiences have shaped his understanding of the challenges posed by modern living, leading him to emphasize the importance of reconnecting with our ancestral roots for improved health. The discussion delves into the impact of modern consumerism on health, particularly through the lens of the footwear industry and its profit-driven motives. Krasno advocates for a mindset shift in how we perceive and respond to stressors, highlighting the physiological responses to stress and the necessity of self-imposed stressors for emotional regulation. The episode concludes with reflections on the misaligned incentives in health and the empowering notion of agency in shaping our health trajectories, along with insights into Krasno's upcoming initiatives in the wellness space.

Jan 15, 2025 • 1h 19min
The Power of Heat and Cold Therapy with Dr. Susanna Søberg
Today I'm speaking with @susannasoeberg on the Longevity Optimization Podcast. In this episode, we delve into the fascinating interplay between cold and heat therapies, exploring their profound effects on metabolism and the crucial role of brown fat in overall health.
Dr. Soeberg is a renowned expert in the field of metabolic health, with a focus on the physiological impacts of temperature exposure. With extensive research on the benefits of cold exposure, she has contributed significantly to our understanding of how these therapies can enhance insulin sensitivity and mental well-being. Throughout the conversation, we discuss practical advice for beginners interested in cold plunging, the gender differences in brown fat, and the physiological mechanisms activated by cold therapy. Dr. Soeberg also emphasizes the importance of internal strength and stress management, providing insights into optimal protocols for cold plunging and the cardiovascular benefits of sauna use.
Dr. Susanna Søberg
Winter Swimming: The Nordic Way Towards a Healthier and Happier Life: https://amzn.to/3MsyxW0
The Soeberg Institute: https://www.soeberginstitute.com
Publications: https://www.soeberginstitute.com/rese...
Twitter: https://x.com/SusannaSberg1
Facebook: / susannasoeberg
YouTube: / @susannasoeberg
TikTok:/susanna_soeberg
Instagram: https://www.instagram.com/susanna_soe...
Timestamps
00:00 Introduction to Longevity and Health Optimization
05:10 Exploring Cold and Heat Therapies
09:27 Understanding Brown Fat and Its Role
12:52 Metabolism: Factors and Influences
15:10 Gender Differences in Brown Fat
18:00 Personal Experiences with Cold Therapy
22:16 Mechanisms of Cold Therapy
27:23 Getting Started with Cold Plunging
30:19 The Aftermath: Natural Warming and Metabolism
32:10 Insulin Sensitivity and Cold Exposure
35:29 Mental Health Benefits of Cold Therapy
39:17 Cold Shock Proteins vs. Heat Shock Proteins
40:44 The Power of Internal Strength and Stress Management
42:40 Understanding Shivering and Cold Plunging
44:06 Optimal Cold Plunge Protocols
46:32 Women and Cold Therapy: Cycle Considerations
49:55 Physiological Differences: Men vs. Women in Cold Exposure
55:01 Sauna Benefits and Cardiovascular Health
01:01:18 Cultural Perspectives on Sauna Use
01:05:35 Hydration and Sauna Practices
01:12:12 Timing and Routine for Sauna and Cold Plunge
01:14:57 Stress Management and Cold Therapy
01:16:52 Future Research Directions in Cold Therapy

Jan 9, 2025 • 51min
Red Light Therapy with Forrest Smith
Today I'm speaking with Forrest Smith from Kineon, exploring the transformative potential of red light therapy, also known as photobiomodulation. We discuss the mission behind this innovative technology, its applications in pain management, and the significant benefits it offers for both male and female health. Our conversation delves into the science of wavelengths, the systemic effects of targeted therapy, and the exciting future of light therapy products.
Forrest Smith is a leading figure at Kineon, a company at the forefront of developing cutting-edge light therapy products. With a focus on optimizing health and well-being, Forrest shares insights into personal experiences and protocols for using light therapy to enhance mitochondrial function and reduce inflammation.
Shop Kineon Here: https://www.k7ghd8dt.com/KAYLAFS/
Use code: KAYLAFS to save!
Timestamps
00:00 Introduction to Red Light Therapy
03:14 The Mission Behind the Technology
05:54 Understanding Photobiomodulation
09:08 Wavelengths and Their Impact
12:02 Remote Photobiomodulation and Systemic Benefits
14:48 Addressing Female Health Issues
18:01 Protocols for Gut and Brain Health
20:56 The Future of Light Therapy Products
23:51 Personal Experiences and Protocols
26:53 The Science Behind Mitochondrial Function
29:58 Conclusion and Future Directions

Jan 2, 2025 • 53min
Ovarian Longevity with Dr. Jennifer Garrison, PhD
Today I'm speaking with Jennifer Garrison, PhD, about her groundbreaking research on ovarian aging and its implications for female health. She emphasizes the importance of understanding the brain-ovary connection and how ovarian health impacts overall health span. Our conversation highlights the need for more research in female physiology, the challenges faced in the field, and the exciting innovations on the horizon for women's health.
Jennifer Garrison, PhD, is a renowned scientist specializing in the study of aging and female reproductive health. Her work focuses on uncovering the intricate connections between the brain and ovaries, aiming to improve health outcomes for women as they age. Dr. Garrison is a leading voice in advocating for increased research in female physiology and is at the forefront of developing innovative solutions for women's health issues.
Timestamps
00:00 Introduction to Longevity and Female Health
05:07 The Science of Ovarian Aging
09:54 Understanding the Brain-Ovary Connection
14:58 Research and Innovations in Female Health
20:05 Future Directions in Ovarian Health Research
27:05 The Importance of Biomarkers in Women's Health
30:26 Understanding Biological Age and Its Implications
31:18 Empowering Women Through Knowledge of Their Physiology
33:34 Diet, Exercise, and Ovarian Health
34:56 The Role of Hormone Therapy in Women's Health
38:10 Genetics and Menopause: What We Know
40:59 Funding Challenges in Women's Health Research
51:21 Innovative Fundraising Ideas for Women's Health

Dec 12, 2024 • 54min
Metabolic Health and GLP-1s with Dr. Tyna Moore
Today I’m speaking with Dr. Tyna Moore about the importance of individualized medicine in modern healthcare. In this episode, we discuss her insights on metabolic health, GLP-1 agonists, and the challenges practitioners face in a landscape dominated by influencers and generalized protocols. Dr. Moore emphasizes the value of tailoring medical approaches to meet individual needs and creating meaningful, patient-centered solutions.
Dr. Tyna Moore is a naturopathic physician and chiropractor with a strong focus on metabolic health and resilience. Known for her science-based and practical perspectives, she is a leading advocate for personalized medicine and proactive healthcare strategies.
Timestamps
00:00 Foundational Metabolic Health
12:03 The Role of GLP-1s in Health Optimization
24:11 Understanding Metabolic Health and Its Factors
27:27 Navigating Hormonal Health and Patient-Centric Care
31:15 The Importance of Muscle and Strength Training
37:40 Chronic Illness and the Role of Metabolic Health
42:39 Balancing Conventional and Holistic Approaches to Health
49:11 Practical Strategies for Sustainable Health
Instagram: https://www.instagram.com/drtyna/Free Ozempic Uncovered Course: https://www.drtyna.com/ozempicuncoveredWebsite: https://www.drtyna.com

Dec 12, 2024 • 54min
Female Training and Exercise Protocols with Dr. Stacy Sims
Today I’m speaking with Dr. Stacy Sims, a leading expert in exercise physiology and nutrition science, to delve into the unique physiological differences between men and women. In this episode, we explore how the menstrual cycle impacts women’s training and performance, and the critical need for personalized exercise regimens tailored to different stages of a woman’s life. Dr. Sims shares her groundbreaking insights on optimizing health and performance for women through science-backed strategies.
Dr. Stacy Sims is an acclaimed researcher, author, and speaker specializing in women’s health and performance. Known for her mantra, “Women are not small men,” Dr. Sims focuses on empowering women with the knowledge to harness their physiology for optimal training, nutrition, and well-being. With years of experience in academia and practical application, she is a pioneer in redefining the approach to female-specific health and fitness.
Follow Dr. Sims Here
Chapters
00:00 Introduction to Female Health and Exercise
02:46 Understanding Female-Specific Physiology
05:54 Differences in Exercise Protocols for Women
09:04 The Impact of Menstrual Cycle on Training
11:58 Training Through Different Life Stages
14:49 Nutrition and Iron Needs During Menstruation
18:09 Building a Sustainable Training Routine
20:54 Creating a Community for Female Health Optimization
27:15 The Importance of Strength Training and Recovery
30:31 Training Cycles and Adaptation Strategies
32:21 Mobility and Stretching: Key to Injury Prevention
33:46 Empowering Women Through Compound Movements
36:34 Bone Health and Strength Training for Women
38:57 Nutrition: The Best Approach for Women
44:06 Recovery Modalities: Sauna and Cold Plunge Benefits
47:54 Sleep Needs and Circadian Rhythms in Women
50:40 Essential Supplements for Women's Health

Dec 12, 2024 • 59min
The Father of Functional Medicine with Dr. Jeffrey Bland, PhD
Today I’m speaking with Dr. Jeffrey Bland, often referred to as the "father of functional medicine," to explore the transformative principles of this healthcare approach. In this episode, we dive into the root causes of health issues, focusing on autoimmunity in women and the critical role of rejuvenating the immune system. Dr. Bland shares actionable insights on how dietary choices and lifestyle changes can redefine our approach to health and wellness.
Dr. Jeffrey Bland is a world-renowned biochemist, educator, and the founder of the functional medicine movement. With decades of experience, he has dedicated his career to advancing a science-driven approach to health that prioritizes personalized care and addressing the root causes of disease. Dr. Bland’s work has inspired a global shift toward integrative and proactive healthcare solutions.
Follow Dr. Jeffrey Bland Here
Timestamps
00:00 Introduction to Functional Medicine
03:06 The Birth of Functional Medicine
05:53 Defining Functional Medicine
09:13 The Importance of Root Cause Analysis
12:02 Understanding Autoimmunity in Women
14:51 Rejuvenating the Immune System
18:09 The Role of Diet in Immune Health
20:53 Biomarkers and Immune Function
24:09 Protocols for Immune Rejuvenation
26:59 The Future of Food and Health
29:39 The Interconnectedness of Microbiomes
32:29 Sustainable Farming Practices and Economic Models
36:45 Exploring Nutritional Innovations
39:56 Personalized Nutrition and Diets
42:17 Gut Health and Autoimmunity
45:34 The Role of Antibiotics in Gut Health
53:48 Nature Therapy and Health Benefits