Longevity Optimization with Kayla Barnes-Lentz

Ovarian Longevity with Dr. Jennifer Garrison, PhD

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Jan 2, 2025
Dr. Jennifer Garrison, PhD, is a research scientist specializing in ovarian aging and brain-ovary signaling. In this engaging discussion, she explores how ovarian health impacts overall well-being and the urgent need for more research in female physiology. Garrison dives into the fascinating brain-ovary connection, innovative biomarkers for women's health, and the significant lifestyle factors affecting ovarian aging. She also discusses the promise of hormone therapy and the importance of empowering women to understand their physiology.
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INSIGHT

Hypothalamus As Aging Hotspot

  • The hypothalamus acts as the brain's master regulator and ages unevenly, becoming an inflammation hotspot.
  • Jennifer Garrison links hypothalamic inflammation to early changes in homeostasis, including reproductive function.
ANECDOTE

Donor Sparked The Research Center

  • The Biaco Foundation donor catalyzed the Buck Institute center for female health research.
  • That philanthropy prompted Garrison to reconsider her own body in her early 40s and launch the work.
INSIGHT

Ovaries Age Faster Than Other Organs

  • Ovaries share aging pathways with other tissues but age at least twice as fast.
  • This accelerated ovarian aging shortens female healthspan despite longer female lifespan.
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