
Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas
Ever wanted to know how music affects your brain, what quantum mechanics really is, or how black holes work? Do you wonder why you get emotional each time you see a certain movie, or how on earth video games are designed? Then you’ve come to the right place. Each week, Sean Carroll will host conversations with some of the most interesting thinkers in the world. From neuroscientists and engineers to authors and television producers, Sean and his guests talk about the biggest ideas in science, philosophy, culture and much more.
Latest episodes

43 snips
Apr 28, 2025 • 3h 38min
AMA | May 2025
In a heartfelt Ask Me Anything session, questions reveal stories of hope, like Puck the Cat's adoption journey. The blend of science fiction and AI sparks discussions on creativity and existential musings. The complexities of consciousness are challenged through physicalism and emergentism, while cosmology shines light on dark matter and the expanding universe. Topics range from visa injustices for international students to the balance of humor in speeches, all while emphasizing the importance of civic engagement and moral responsibilities in science.

46 snips
Apr 21, 2025 • 1h 31min
312 | Thomas Levenson on the Mutual History of Humans and Germs
In this enlightening conversation, Thomas Levenson, a science writing professor at MIT, dives into the captivating journey of germ theory. He discusses how early microscopists like Anton van Leeuwenhoek laid the groundwork for modern microbiology, despite societal skepticism. The shift from miasmas to microbes in understanding disease is fascinating, especially in light of historical events like the Great Plague. Levenson also highlights the critical role of scientists like Semmelweis, and the ongoing public health challenges we face today in managing infectious diseases.

106 snips
Apr 14, 2025 • 1h 10min
311 | Annaka Harris on Whether Consciousness is Fundamental
Annaka Harris, author of 'Conscious: A Brief Guide to the Fundamental Mystery of the Mind,' dives into the profound intricacies of consciousness. She explores whether consciousness is a product of brain activity or a fundamental aspect of reality. The conversation touches on split-brain research, the relationship between memory and self, and even questions the potential for AI consciousness. Harris advocates for open dialogue in understanding these complex ideas, bridging neuroscience and philosophy to illuminate the mysteries of the mind.

45 snips
Apr 7, 2025 • 3h 30min
AMA | April 2025
In this engaging AMA session, the speaker tackles pressing issues like government tariffs and civil liberties, spotlighting a student's troubling arrest by ICE. The discussion dives into quantum mechanics and its implications for understanding reality, alongside reflections on mental health accessibility. Voter rights, the complexities of democracy in the AI age, and the interplay between science and personal belief systems are thoughtfully explored. The conversation balances serious topics with listener questions, creating a rich tapestry of insight and inquiry.

104 snips
Mar 31, 2025 • 1h 26min
310 | Marc Kamionkowski on Dark Energy and Cosmic Anomalies
Marc Kamionkowski, a leading cosmologist at Johns Hopkins University, dives into the intriguing realm of dark energy and cosmic anomalies. He discusses the shocking 1998 discovery that the universe is accelerating, exploring the implications of the cosmological constant and its puzzlingly small value. Kamionkowski shares insights on the Hubble tension—discrepancies in the universe's expansion rates—and the potential for dark energy to vary over time. Their conversation showcases the ongoing battle to decode the universe's mysteries through collaborative scientific efforts.

159 snips
Mar 24, 2025 • 1h 21min
309 | Christof Koch on Consciousness and Integrated Information
Christof Koch, a renowned neuroscientist and the Chief Scientist at the Allen Institute for Brain Science, dives into the complexities of consciousness. He explores Integrated Information Theory, proposing a mathematical approach to understanding conscious awareness. The conversation touches on the interplay between consciousness and artificial intelligence, emphasizing its unique qualities that AI struggles to replicate. Koch also discusses the philosophical implications of consciousness, advocating for a deeper understanding of its neural correlates and how they shape our reality.

226 snips
Mar 17, 2025 • 1h 10min
308 | Alison Gopnik on Children, AI, and Modes of Thinking
In this engaging conversation, Alison Gopnik, a professor at UC Berkeley and expert in child development, reveals the unique cognitive abilities of children compared to adults. She suggests that kids are natural explorers, fostering creativity through curiosity. Gopnik discusses the implications for AI, emphasizing how understanding childhood thinking can innovate machine learning. The dialogue touches on the roles of caregivers, social learning, and the significance of early cognitive milestones, painting a rich picture of how human intelligence evolves.

118 snips
Mar 10, 2025 • 2h 58min
AMA | March 2025
In March 2025, listeners dive into exciting discussions about scholarship winners and how to craft a petrichor-inspired cocktail. The impact of funding cuts in science and global power shifts are explored, along with the complexities of democracy and the nuances of consciousness in nations. Conversations also traverse Bayesian reasoning related to extraterrestrial life and the intricacies of quantum information. The challenges facing academia are highlighted, alongside intriguing debates about social media dynamics and perceptions of scientific inquiry.

74 snips
Mar 3, 2025 • 1h 17min
307 | Kevin Peterson on the Theory of Cocktails
In this engaging conversation, Kevin Peterson, a scientist-turned-mixologist with a Ph.D. in Mechanical Engineering, delves into the intriguing science behind crafting cocktails. He explains how balance, temperature, and flavor ratios are critical to creating the perfect drink. Peterson also shares insights from his Cocktail Genome Project, which personalizes cocktails based on individual preferences. The discussion highlights the fusion of artistry and science in mixology, making it clear that cocktail crafting is both a sensory and technical endeavor.

111 snips
Feb 24, 2025 • 1h 12min
306 | Helen Czerski on Our Energetic Oceans
Helen Czerski, an ocean physicist and Associate Professor at UCL, dives into the complexities of our oceans. She dispels the myth that we understand them less than the moon, highlighting their intricate ecosystems and unique interspecies relationships. Czerski discusses the challenges of traditional physics in studying ocean dynamics, stressing the role of temperature and salinity in creating distinct layers. She underscores the impact of human activities on these vital systems and calls for advancements in ocean science to ensure a sustainable future.
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