
This Week in Startups
Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.
Latest episodes

49 snips
May 15, 2025 • 1h 7min
Chime’s IPO, Databricks’ $1B Acquisition & Dave Rubin’s Media Empire | E2126
Dave Rubin, a prominent political commentator and host of The Rubin Report, dives into the challenges and triumphs of building Locals, an independent creator platform. He shares insights on why he goes phone-free for weeks and the detrimental effects of identity politics on business and sports. The conversation also touches on the fast-evolving landscape of right-wing media and the need for mental health breaks. Rubin advocates for innovative subscription models in the entertainment sector, while exploring generational tensions amidst a polarized cultural landscape.

111 snips
May 13, 2025 • 52min
Agentic AI Meets Cybersecurity + Solar Robots in the Desert | E2125
Aaron Walls, founder of ZioSec, discusses their pioneering work on cybersecurity for AI agents, emphasizing the importance of proactive testing to preemptively address vulnerabilities. Matt Campbell from Terabase highlights how mobile robotic factories are revolutionizing solar energy deployment, allowing massive solar farms to be built directly in the desert. Together, they explore the synergy between advanced technologies and renewable energy, both critical for a sustainable future.

57 snips
May 13, 2025 • 1h 31min
Anti-Work Uprising, Copyright Wars & the StreamFog Solution | E2124
In a fiery discussion, the hosts debate the anti-work movement and its implications for the future of labor. They explore the alarming statistics surrounding startup funding, particularly the challenges in moving from seed to Series A. Excitingly, a new AI rights licensing platform is introduced, aiming to protect creators in the evolving copyright landscape. The conversation shifts to the high-profile valuation of Perplexity and discusses the potential impact of geopolitical forces on the tech sector, particularly regarding antitrust issues and the role of big companies.

73 snips
May 10, 2025 • 1h 13min
OpenAI Scoops Instacart’s CEO, AI in the Courtroom & Off-Road Startups | E2123
OpenAI makes waves by hiring Instacart's former CEO, raising eyebrows in the tech community. The ethical quagmire of using AI avatars in court sparks a heated discussion about the future of legal testimony. Late-stage funding is redefined, proving that a 'Series G' doesn't always mean trouble for startups. Plus, insights from 'The Checklist Manifesto' shed light on the importance of systematic approaches. Lastly, a spotlight on WhereToWheel ignites excitement in the off-road startup scene!

40 snips
May 8, 2025 • 1h 7min
Zoox Crash Fallout, COATUE’s $1B Open Fund, and Office Hours with FusionAds | E2122
Evan Graj, founder of FusionAds, discusses how AI is reshaping marketing for small businesses by simplifying ad creation. He shares insights on fostering client trust in AI-generated advertisements. The conversation also covers COATUE's new innovative venture fund aimed at democratizing investment access. Additionally, the podcast kicks off with a deep dive into Zoox's recent robo-taxi recall, Uber's impressive earnings, and the vital need for companies to adapt to AI as Fiverr's CEO emphasizes the urgency of embracing automation.

17 snips
May 6, 2025 • 1h 26min
Cursor’s $9B Round, AI-Powered Toys & CloudNuro’s SaaS Fix | E2121
Fateen Anam Raffid, founder of Magical Toys and creator of the AI-powered dinosaur toy, Dino, dives into the intersection of technology and playtime, discussing how AI can enhance children's engagement. Shyam Kumar, co-founder of CloudNuro, addresses the complexities of managing SaaS expenses in today's tech landscape. They explore innovative coding trends like ‘vibe coding’ and tackle challenges in product development, while also reflecting on the ethical considerations of using AI in toys. Expect humor, insights, and entrepreneurial wisdom!

59 snips
May 2, 2025 • 1h 15min
Apple’s App Store Loss, AI Persuasion, and an Interview with Tyler Denk of Beehiiv | E2120
Tyler Denk, Co-founder and CEO of Beehiiv, shares insights on building successful email newsletter platforms in a competitive landscape. The conversation highlights a recent legal win for startups against Apple, suggesting a shift in app store dynamics. They also discuss AI's ability to outpace humans in changing minds on online platforms, revealing a transformative moment in digital dialogue. Tyler emphasizes the importance of iterating products quickly and the challenges of innovating too rapidly, providing key takeaways for ambitious founders in a fast-changing tech world.

135 snips
May 1, 2025 • 28min
What's Next for AI Infrastructure with Amin Vahdat | AI Basics with Google Cloud
In this discussion, Amin Vahdat, VP of ML at Google Cloud, shares his insights on the groundbreaking infrastructure behind AI. He explains how Google’s TPUs are revolutionizing real-time data processing and enhancing AI capabilities. Vahdat predicts 2025 as the pivotal 'Year of Inference' for startups. He highlights advancements in low-code development, the evolution of AI agents, and the transformative potential of cloud computing. Dive in to explore how technology is reshaping decision-making and creating opportunities for entrepreneurs!

42 snips
May 1, 2025 • 1h 5min
Bittensor’s Rise, Meta’s Llama Goes Cloud, & AI Now Writes Your Code | E2119
Mark Jeffrey, an early Bitcoin investor and host of the Hash Rate podcast, dives into the rise of Bittensor, a decentralized AI compute network aimed at revolutionizing the industry. He discusses its potential as a viable alternative to traditional cloud services and its similarities to Bitcoin. The conversation also covers Meta's strategic moves in AI and cloud computing, including its new partnerships and challenges. Additionally, AI's growing role in coding signifies a major shift in software development, raising interesting implications for tech companies.

70 snips
Apr 29, 2025 • 1h 27min
Meta’s Dangerous Chat, Protect AI & Founder Fridays Pitch Comp | E2118
Osmaan Shah, Co-founder and CEO of Formulate, shares his vision for a groundbreaking robotic kitchen that automates the creation of chemistry-driven products like cosmetics. The discussion dives into the ethical concerns surrounding Meta's AI chatbots, especially their dangerous interactions with minors. They also cover Palo Alto Networks’ significant acquisition of Protect AI for enhanced generative AI security. The conversation touches on the influence of secret tech group chats and whether AI can outpace humans in fixing code.