This Week in Startups

How decriminalization led to an explosion in cannabis startups (Feat. Ford Smith, Andrew Duffy, and Socrates Rosenfeld) | E2241

19 snips
Jan 29, 2026
Andrew Duffy, founder of Sparkplug building retail incentives and inventory tools. Socrates Rosenfeld, founder of iHeartJane running a cannabis marketplace. Ford Smith, investor and operator in cannabis consumer products. They debate rescheduling and federal vs state rules. They unpack industry growth, capital cycles, and rising product potency. They cover safety, regulation, and how cannabis consumption is shifting from alcohol.
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INSIGHT

Rapid Growth And Physical Retail's Role

  • The U.S. cannabis market grew from ~$3B to ~$30B in a decade, driven by state liberalization and COVID tailwinds.
  • Andrew Duffy says physical retail still handles 80%+ of commerce, creating big wholesaler-retailer opportunities.
INSIGHT

Hemp Loophole Reshaped The Market

  • The 2018 Farm Bill legalized hemp (<0.3% THC) and created a federal loophole enabling concentrated THC products via hemp extraction.
  • Ford Smith explains hemp commercialization let brands ship D2C and run normal CPG ads, changing competitive dynamics.
ANECDOTE

Building An Amazon For Main Street

  • Socrates built Jane to digitize local dispensary inventory and deliver an Amazon-like experience for local stores.
  • He says the platform turns store shelves into turnkey digital storefronts and links them for consumers.
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