The OptimalWork Podcast

#277: In this conversation, Sharif and Kevin delve deeper into the dynamics of human growth and why progress often feels nonlinear. Drawing from chaos theory, they explore the idea of “valleys” and “vortexes” of anxiety, depression, and addiction—and how a single loving, willing action in the present moment can reverse even the strongest downward momentum. Kevin explains how vitality emerges from embracing challenges rather than seeking relief, and how the same simple move sustains resilience whether someone is studying for finals or facing a personal crisis. This episode offers a practical and empowering map for anyone who wants confidence that they really are growing, even when circumstances get harder.Find more at https://OptimalWork.com

#276: In this conversation, Sharif Younes and Dr. Kevin Majeres introduce the idea of “strange attractors” as a framework for understanding why people can abruptly shift between vitality and states like anxiety, depression, or addiction. Drawing from chaos theory, Kevin explains how meaning, effort, and attention can lock into recognizable behavioral patterns—some virtuous, some vicious—that scale from a moment to an entire life. Sharif and Kevin explore how “signature moves” define each valley, why people can feel stuck even when they're doing everything right, and how small acts of willingness at key transition points (“saddle points”) can redirect the whole system toward vitality. This is the first episode in a series unpacking these dynamics and how to apply them in real life.Find more at https://OptimalWork.com

#275: In this episode, Sharif and Kevin explore how the cortex and attention form the capstone of motivation and enthusiasm. Together, they trace how meaning (the septum), willingness (the striatum), and focused presence (the cortex) work in harmony to create clarity, silence, and smoothness: the hallmarks of deep attention and flow. Kevin explains why distractions arise, what inner “friction” really signals, and how love and service fuel the brain’s attentional systems. This conversation offers a vivid look at how desire, silence, and love form a virtuous cycle in work and life.Find more at https://OptimalWork.com

#274: In this follow-up to their discussion on meaning and the septum, Sharif and Kevin turn to the striatum—the brain’s engine of effort and challenge. Kevin explains how our willingness to act depends on dopamine, and how love, purpose, and embracing discomfort transform drudgery into freedom and flow. They contrast this neuroscience-based approach with Stoicism, showing how the key to persistence isn’t suppressing emotion but letting meaningful motivation drive every action.Find more at https://OptimalWork.com

Dr. Kevin Majeres, a clinician and neuroscience scholar, delves into the pivotal role of the brain's septum in fostering motivation and meaning. He discusses 'septal resonance,' linking deep personal connections to our work passion. Practical methods like gratitude journaling and loving-kindness meditation are highlighted as ways to activate motivation. Kevin also introduces exercises to clarify personal ideals, emphasizing how to shift from a threat mindset to one of vitality and engagement. Tune in for insights that spark enthusiasm in both your career and spiritual life.

#272: In this episode, Sharif and Kevin continue their exploration of depression, burnout, and low energy—this time uncovering a remarkable bridge between neuroscience and classical wisdom. Kevin reveals how adenosine’s “good tired” and “bad tired” states map directly onto Aquinas’ ideas of tristitia and acedia, showing that what medieval thinkers called “weariness of soul” may be the same state modern science calls burnout or depression. Together, they unpack Aquinas’ five treatments for sadness—pleasure, friends, contemplation, sleep, and tears—and show how each one perfectly targets a modern neurobiological pathway of vitality, meaning, effort, and attention.Find more at https://OptimalWork.com

#271: In this episode, Kevin and Sharif explore one of the most elegant parallels in psychiatry — the deep connection between anxiety and depression. Kevin explains how panic disorder can be seen as a phobia of adrenaline, while depression mirrors it as a phobia of adenosine, the brain’s “tiredness” signal. Together, they explore how unwillingness to feel these sensations fuels both disorders, and why willingness—even love—toward the very sensations we resist becomes the key to healing. With striking clarity, Kevin shows how practices like focused work, rhythmic rest, and embracing “good tired” can reverse the spiral of depression and restore energy, meaning, and joy.Find more at https://OptimalWork.com

#270: In this episode, Kevin and Sharif explore a bold new way to understand depression—not as a simple chemical imbalance, but as what Kevin calls a “phobia of adenosine.” Drawing on neuroscience and behavioral psychology, Kevin explains how our brains rely on a natural rhythm of intensity and rest, and how losing that rhythm leads to burnout, lethargy, and despair. The discussion connects deep biological mechanisms—adenosine, dopamine, cortisol, and dynorphins—to everyday experiences of tiredness, motivation, and meaning. In this episode, the groundwork has been laid for next week’s episode which will explain how to restore vitality through a rediscovery of “good tired”: meaningful effort and healthy rest.Find more at https://OptimalWork.com

#269: Kevin and Sharif dive deep into the true biology and psychology of burnout — not as mere exhaustion, but as “bad tired on steroids.” Kevin explains how chronic threat mode floods the brain with cortisol, amplifying the “type two” tiredness that crushes motivation, focus, and connection. Together, they explore the three engines of vitality — meaning, effort, and attention — showing how burnout arises when these engines fall out of sync. Sharif presses on the dilemma of working hard without seeing results, while Kevin reveals how reconnecting work with love and service can transform fatigue into renewal. It’s a fascinating look at how neuroscience and reframing unite to reignite purpose in daily life.Find more at https://OptimalWork.com

Explore the intriguing distinction between 'good tired' and 'bad tired,' tied to different brain states influenced by adenosine and dopamine. Discover practical strategies to manage energy, like focusing on love-driven motives, structured sprints with breaks, and mindful unit-tasking. Learn how to reset during a workday with effective breaks involving light, movement, and hydration. This insightful conversation offers tools to help you transform fatigue into productive energy, setting the stage for deeper discussions on burnout.