Dr. Sophie Shotter Dr. Sophie and Fiona discuss: • How mushrooms help skin • Beta glucan • Adaptogens • Kojic acid and hyperpigmentation • Reishi’s anti-inflammatory (and hydrating) properties • Tremella (snow mushroom) and hyaluronic acid • Reishi • Mycelium and sustainable beauty • Stella McCartney’s mushroom leather bag • Origins and the iconic Mega Mushroom treatment oil • Other brands using mushrooms • Mushrooms as a supplement – inc. the immune system / cognitive function • Mushrooms and glutathione (antioxidant) – plus liver function • Lion’s mane – and anxiety and depression / sleep • Mushroom extraction processes • Different supplementation brands • Understanding reishi’s potential side effects • Curcumin and cellular health • Green tea and EGCG Find out more by heading to https://drsophieshotter.com/ Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en This podcast was produced by https://thepodcastpeople.co/ Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here: Reishi inhibits the melanin-producing enzyme tyrosinase so is helpful in reducing skin pigmentation and discoloration. A 2016 study found that mushrooms helped combat ageing, reduce skin disease inflammation and correct hyperpigmentation. A 2019 study found that the beta-glucan in mushrooms helps improve the skin barrier and fight ageing with antioxidants. https://www.sciencedirect.com/science/article/abs/pii/S092666901630396X https://digitalaesthetics.co.uk/news/news/mushrooms-in-the-beauty-industry#:~:text=A%202016%20Study%20on%20Industrial,and%20fight%20ageing%20with%20antioxidants. In the UK, a company called Magical Mushroom uses mycelium to create packaging for various brands. Boots Botanicals range uses mushrooms in its micellar water. Kiehl’s uses sustainably grown chaga to help even out skin tone and boost radiance in its Super Multi-Corrective Cream. Charlotte Tilbury used mushroom extract in her foundation back in 2016. Meder Beauty’s Red-Apax Concentrate contains a truffle called Albatrellus ovinus extract, also called northern truffle, and this has been formulated to combat redness / rosacea, and has been proven to reduce discoloration and calm skin. Meder also have mushrooms also in their Equaderm cream. SkinBetter has tremella in its TechNO neck perfecting cream and white mushroom extract in its EyeMax cream. The Neostrata Dark Spot Corrector has Kojic acid. Murad has mushrooms in their Invisiblur Perfecting Shield SPF 30. Paula’s Choice has mushrooms in the Super Hydrate Overnight Mask. And there’s an interesting looking cleanser by Kora - milky mushroom cleansing oil. There are also niche, boutique brands such as FRWRD Skincare whose hero product is the Organic Mushroom Super Serum which also promises to calm sensitive skin, reducing redness and breakouts. Shroom Skincare have blended four mushroom extracts into its Mycelium Glow: Vitamin C & Mushroom Brightening Serum. Neon Hippie uses a proprietary seven-mushroom complex for its range. Youth to the People’s Adaptogen Deep Moisture Cream uses fermented reishi and ashwagandha. Herbar is another new mushroom-based skincare brand. A.P. Chem is an interesting one as it uses what it calls Alt-Pharma ingredients including Polyglutamic Acid and GABA (both found in mushrooms). Their MicroDose Magical Moisturizer has a bit of a cult following and received coverage from Oprah. We mentioned K beauty on our skincare episode - BioRepublic is a Korean beauty–inspired skincare brand that uses snow mushrooms in its organic sheet masks. Alicia Keys has mushrooms in her skincare range which has been developed by dermatologists. Her Promise Serum uses snow mushroom, with zinc and vitamin B3. Q+A Zinc PCA Facial Serum is made with reishi and shiitake and it’s (currently) only £9 so good for a budget buy. Ren’s Redness Relief Serum uses white mushroom extract and is very popular with those who have rosacea. More info… Mushrooms are high in glutathione, an antioxidant and detoxifying nutrient, as well as ergothioneine, which protects DNA from oxidative damage. Plus mushroom polysaccharides have a significant impact on the immune system and are even said to fight viruses, bacteria and other pathogens. Reishi has been shown to help de-stress and create deeper, better sleep – but only if used regularly. Lion's mane has typically been used in supplements for brain health, but Origins are said to be looking at developing formulations for topical use because of its antioxidant benefits. Some other hero ingredients include: Ashwaganda – it’s been claimed it can reduce anxiety by up to 44%. Chaga - contains vast amounts of antioxidants and is praised for boosting immunity and slowing down the ageing process. Maca - is linked to libido and sexual function. Shilajit – is said to balance sex hormones. Lots of these are available in powders that can be added to smoothies or coffee or foods. Always look for certified organic mushrooms that have been “extracted” – that’s key to making sure you’re getting the highest quality with maximum efficacy. Wunder Workshop combine different adaptogens for their super powders. GROWN liquid supplements can either be added to drinks or placed straight onto the tongue. Other brands include: Bristol Fungarium Dirtea The Nue Co Nootro Focus Kiki Health Organic Lion’s Mane Extract Mushroom Inessa Immunity Complex WelleCo The Super Elixir - Daily Greens Pouch Refill Indi Supplements Grass and Co Research demonstrates that curcumin activates certain proteins that help delay cellular senescence and promote longevity. Plus, some studies demonstrate that it combats cellular damage and significantly increases life span, postponing age-related disease and symptoms. Green tea contains a polyphenol called Epigallocatechin gallate (EGCG). EGCG restores mitochondrial function in cells and acts on pathways involved in aging. It also induces autophagy, the process by which the body removes damaged cellular material. Plus, there may be an association between green tea intake and protection against aging skin, as well as reduced hyperpigmentation caused by ultraviolet (UV) light. Further reading: https://www.healthline.com/nutrition/anti-aging-supplements#1.-Curcumin https://www.vogue.co.uk/beauty/article/mushroom-skincare-trend https://www.dailymail.co.uk/femail/beauty/article-11742579/How-humble-mushrooms-skincare-magic.html https://www.elle.com/beauty/g42695414/mushroom-skincare/ https://wwd.com/beauty-industry-news/beauty-features/mushrooms-beauty-wellness-supplements-skin-care-1234794653/ https://www.harpersbazaar.com/uk/beauty/skincare/g43493836/mushroom-skincare/ https://www.dazeddigital.com/beauty/article/42740/1/mushroom-beauty-industry-latest-trip-products https://www.byrdie.com/mushroom-tea-4766737 https://www.byrdie.com/adaptogenic-mushroom-powder-benefits https://www.dazeddigital.com/beauty/article/47739/1/skincare-mushroom-products-alumier-lush-moon-juice-ren https://blog.frwrdskincare.com/posts/chaga-mushroom-for-anti-aging-and-skin-cell-renewal https://blog.frwrdskincare.com/posts/tremella-mushroom-for-plumping-and-firming-skin https://www.wonderflaw.com/mushrooms-the-new-it-ingredient/ Some studies: http://www.doi.org/10.14336/AD.2017.0410 https://doi.org/10.1615/IntJMedMushrooms.2018028370 https://doi.org/10.1007/s13205-011-0036-2 https://doi.org/10.1089/jmf.2005.8.53 https://doi.org/10.3390/molecules190913473 The content in this podcast is for general information purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast.

Dr. Sophie Shotter Dr. Sophie and Fiona discuss: • The ‘male gaze’ in films and TV • Is it possible to be a feminist and have injectables? • The language of looking good [for your age] • Self esteem • Body dysmorphic disorder • The critical importance of a consultation • New attitudes to ageing • Saying no to a client • Managing clients’ expectations • Avoiding the overdone or ‘done’ look • Are aesthetic treatments too accessible? • A serious lack of UK regulations in aesthetics • Cheap packages that aren’t (always) safe • Does everyone want to look the same? • The role of social media and filters • Celebrities and surgery (their right to privacy?) • Robbie Williams • Affordability • People’s fear of injectables • Keeping treatments and tweakments a secret • Men and aesthetics • Body dysmorphic disorder (see below for support) Find out more by heading to https://drsophieshotter.com/ Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en This podcast was produced by https://thepodcastpeople.co/ Further reading and links are here: An interesting blog from Dr Sophie: https://drsophieshotter.com/these-are-the-skin-treatments-that-will-perfectly-complement-your-injectables-2/ Some of Dr Sophie’s work in campaigning for better care and regulations in aesthetics: https://aestheticmed.co.uk/site/industrynewsdetails/dr-sophie-shotter-cpd-complications-course Robbie Williams article: https://www.independent.co.uk/life-style/robbie-williams-fillers-plastic-surgery-b2388733.html Read this before you book a cheap aesthetics deal: https://www.saveface.co.uk/en/blog/post/sky-news-fillers-false-advertising-and-intimidation-the-ugly-side-of-the-aesthetic-training-industry An explainer on Leslie Ash: https://www.airaesthetics.co.uk/lip-service-what-happened-to-leslie-ash/ Get help and support for body dysmorphic disorder (UK charity): https://bddfoundation.org/ The content in this podcast is for general information purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast.

Dr. Sophie Shotter Dr. Sophie and Fiona discuss: • The connection between good gut health and skin • The skin’s microbiome – should we really be double cleansing? • The impact of skin treatments such as Roaccutane / antibiotics • Gut health and longevity / cellular ageing • Probiotics (the strains you need) • Candida… and IBS • Spore based / soil based probiotics • The vaginal microbiome • Prebiotics • Digestive enzymes • Eating bread • Taking probiotics while on antibiotics • Gut health testing / Zoe / the SIBO test • Acupuncture • Fasting, autophagy, mitophagy • The vagus nerve • Cold water therapy Find out more by heading to https://drsophieshotter.com/ Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en This podcast was produced by https://thepodcastpeople.co/ Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here: Research linking gut dysbiosis to acne, rosacea, eczema, psoriasis, and other skin conditions. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916842/ Gut health and acne https://zoe.com/learn/gut-health-and-acne Two thirds of our immune system lives in our gut https://www.uclahealth.org/news/want-to-boost-immunity-look-to-the-gut A study that indicates isotretinoin (another name for Roaccutane) has no significant (negative) impact on gut microbes https://pubmed.ncbi.nlm.nih.gov/28689869/ Research suggests the health of our gut microbiome largely determines how we will age and the diseases we will either acquire or avoid. https://www.nature.com/articles/nature25973 PLUS https://link.springer.com/article/10.1007/s12602-021-09903-3#:~:text=Studies%20have%20shown%20that%20gut,disorders%20is%20also%20becoming%20apparent Re probiotics: the two main strains you want to look for are: lactobacillus and bifidobacterium. Within these two, there are a lot of different strains. https://www.symprove.com/ < Dr. Sophie's recommendation A healthy vaginal microbiome should be dominated by a good bacteria called lactobacilli, especially the species called lactobacillus crispatus. Some people say that Saccharomyces boulardii really helps candida – it’s a yeast that fights yeast but while it’s helpful for some, others don’t tolerate it well. Read more: https://www.optibacprobiotics.com/uk/professionals/latest-research/gut-health/probiotics-best-for-candida#:~:text=S.,from%20the%20digestive%20tract2%20. Fiona's acupuncturist: John Chadwick (Sidmouth, Devon): johnchadwick@ymail.com An interesting listen: https://podcasts.apple.com/gb/podcast/the-junk-food-doctor-this-food-is-worse-than-smoking/id1291423644?i=1000632239649 https://www.hollandandbarrett.com/the-health-hub/vitamins-and-supplements/supplements/inulin-powder-supplement/ https://www.verywellhealth.com/the-benefits-of-digestive-enzymes-89446 https://zoe.com/ SIBO testing is available in several places such as here: https://healthpath.com/sibo-breath-test/?utm_term=sibo%20test&utm_campaign=SIBO+-+Exact&utm_source=adwords&utm_medium=ppc&hsa_acc=5004928523&hsa_cam=6449023587&hsa_grp=77317475015&hsa_ad=382201416429&hsa_src=g&hsa_tgt=kwd-306464899573&hsa_kw=sibo%20test&hsa_mt=e&hsa_net=adwords&hsa_ver=3&gad_source=1&gclid=Cj0KCQiA67CrBhC1ARIsACKAa8QSdxixKMR9ftSiPCJVan_quuR1D9cn4X_LjE07Yn0Nzv0AmJOqj3EaAnAfEALw_wcB Vagus nerve ear massage https://www.youtube.com/watch?v=9uZ1rnKF5DU The content in this podcast is for general information purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast.

Dr. Sophie Shotter Dr. Sophie and Fiona discuss: • Is acne on the increase (if so, why)? • Girls, women, hormones - and acne • Testosterone / HRT regimes • Cortisol • Dairy • GI loads in diet • The gut health connection • Skin care products • Fungal acne • Niacinamide • Budget skincare ranges • Soolantra • Roaccutane • Antibiotics • Spironolactone • In-clinic treatments • Scarring • DIM (diindolylmethane) • Emergency spot treatments • The mental health factor Find out more by heading to https://drsophieshotter.com/ Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en This podcast was produced by https://thepodcastpeople.co/ Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788264/ https://www.jaad.org/article/S0190-9622(16)30480-7/fulltext#sec4 https://www.health.com/condition/acne/stress-acne https://clinisoothe.com/?utm_source=google&utm_medium=cpc&utm_campaign=13952991541&gclid=Cj0KCQiAr8eqBhD3ARIsAIe-buPEDl7J_6KDoM_OwRxFMoC3U92ATvlSdQJH90NGnsCmsXT5wq45nk4aAj5bEALw_wcB https://www.aad.org/public/diseases/acne/causes/diet https://zoe.com/learn/gut-health-and-acne https://www.cerave.com/skincare/acne https://www.laroche-posay.co.uk/en_GB/effaclar-2 https://www.bioderma.co.uk/skincare/sebium https://www.nhs.uk/medicines/isotretinoin-capsules/ https://practicaldermatology.com/articles/2014-jan/on-dosage-and-diet-isotretinoin-101 https://www.rosacea.org/patients/causes-of-rosacea/demodex-mites-and-microbes https://www.bmj.com/content/381/bmj.p1114 https://aviclear.com/ https://www.allure.com/story/aviclear-review https://zitsticka.co.uk/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354339/#:~:text=Many%20studies%20showed%20high%20prevalence,psychiatric%20comorbidities%20in%20chronic%20diseases. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354339/ Further studies and reading https://jddonline.com/articles/the-role-of-benzoyl-peroxide-in-the-new-treatment-paradigm-for-acne-S1545961613S0073X/#:~:text=Combining%20BP%20with%20a%20topical,resistant%20strains%20of%20P%20acnes. https://www.theguardian.com/fashion/2019/oct/05/the-best-emergency-spot-treatments https://www.theguardian.com/lifeandstyle/2011/aug/19/sali-hughes-acne-treatments The content in this podcast is for general information purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast.

Dr. Sophie Shotter Dr. Sophie and Fiona discuss: • Squalane • Single ingredient products • Vitamin C (inc. stability and dose / formulations) • Niacinamide • Budget friendly vitamin C products • Exfoliating acids (inc. what Dr Sophie uses) • How to exfoliate • Hyaluronic acid • Serums - the lowdown • Dr Sophie’s favourites • Cult products • Alcohol denat • SPF (mineral and chemical) • Neck creams, decolletage, eye creams, night creams • Retinol – the explainer • New molecules and developments in skincare • Exosomes • Dr. Sophie’s skincare heroes • New business models / Beauty Pie • Multitasking skincare v single ingredient products • Skin cycling • Korean skincare • Dr Sophie’s routine • Can any skincare remove wrinkles? The data • A holistic approach Find out more by heading to https://drsophieshotter.com/ Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en This podcast was produced by https://thepodcastpeople.co/ Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here: https://biossance.com/products/100-squalane-oil https://www.laroche-posay.co.uk/en_GB/toleraine-1?start=0&sz=24 https://www.paulaschoice.co.uk/clinical-ultra-rich-moisturizer/m5570.html?dwvar_m5570_size=fullsize&cgid=pregnancy-skincare&reviews=&pr_rd_page=1&aw_account=1510415071&aw_campaign=19592213249&aw_adgroup=&aw_creative=&aw_dev=c&aw_target=&&utm_content=performance_max&gad_source=1&gclid=CjwKCAjw7oeqBhBwEiwALyHLM-cNYfOib6WC4dTz2P8-zmzBfKm7GXFJG5czLgQdm9NIIL8hKKKc9hoCxT8QAvD_BwE https://www.revisionskincare.co.uk/?gad_source=1&gclid=CjwKCAjw7oeqBhBwEiwALyHLMzsnmPxDtNDdrQn4jtjMDvshIja52__h9o6MQer4ZrRe67IqJmiBjhoCe7sQAvD_BwE https://skindiligent.com/products/vitamin-c-serum-in-oil https://www.medik8.com/products/c-tetra https://www.vichy.co.uk/en_GB/liftactiv-supreme-15-pure-vitamin-c-brightening-serum-20ml/VICUK-140.html https://www.neostrata.com/products/collections/restore https://mederbeauty.com/products/enzy-peel-double-action-exfoliating-mask?variant=44619262263570 https://www.vichy.co.uk/en_GB/mineral-89-hyaluronic-acid-hydrating-serum---hypoallergenic-for-all-skin-types/VICUK-014.html https://www.vichy.co.uk/en_GB/mineral-89-probiotic-serum/VICUK-135.html https://mederbeauty.com/products/hydra-fill-concentrate https://www.revisionskincare.co.uk/products/hydrating-serum https://www.neostrata.com/products/aging/tri-therapy-lifting-serum/F30159XA.html https://www.skinbetter.com/shop-skincare/product-category/antioxidants/alto-advanced-defense-and-repair-serum-M006.html https://www.skinceuticals.co.uk/en_GB/c-e-ferulic-vitamin-c-antioxidant-serum-for-visible-signs-of-ageing-30ml/S17.html https://www.esteelauder.co.uk/product/689/77491/product-catalog/skincare/repair-serum/advanced-night-repair-serum/synchronized-multi-recovery-complex https://www.clarins.co.uk/double-serum/C070400090.html https://www.drunkelephant.co.uk/gb/en/collections/serums/ Sophie references avoiding alcohol denat. Here’s a useful article from Paula’s Choice (referencing data and science): https://www.paulaschoice.co.uk/alcohol-in-skincare-the-facts The efficacy and safety of sunscreen use for the prevention of skin cancer - PMC (nih.gov) https://heliocare.co.uk/products/mineral-tolerance-fluid https://www.esthederm.com/en/suncare/by-range/solar-range.html https://www.laroche-posay.co.uk/en_GB/sun-care-face https://www.revisionskincare.co.uk/collections/treat-neck/products/nectifirm-advanced https://www.skinbetter.com/shop-skincare/product-category/neck-care/techno-neck-perfecting-cream-M013.html The Medik8 range in three sections: https://www.medik8.com/collections/shop-by-retinol https://www.medik8.com/collections/shop-by-retinaldehyde https://www.medik8.com/collections/shop-by-retinyl-retinoate A retinol alternative if you’re pregnant: https://edit.sundayriley.com/alternatives-to-retinol-during-pregnancy/ https://www.skinbetter.com/shop-skincare/product-category/anti-aging/alpharet-overnight-cream-M001.html https://amp-uk.co.uk/exoe/ https://www.obagi.com/ Two new skincare launches to look out for: https://sentelabs.com/ https://www.biojuve.co.uk/ https://www.beautypie.com/ The ones Sophie always has in the rotation: https://www.revisionskincare.co.uk/products/d-e-j-daily-boosting-serum%E2%84%A2?_pos=1&_sid=35655adf0&_ss=r&gad_source=1&gclid=CjwKCAjw7oeqBhBwEiwALyHLM1LXfuwrcGrGrOW05wulykZ99fQc6Nq6_IXid-51ppcNNNXS8nS5XhoCJMsQAvD_BwE https://www.revisionskincare.co.uk/products/c-correcting-complex-30?gad_source=1&gclid=CjwKCAjw7oeqBhBwEiwALyHLM0qGLtVUmk3X_rTk_tLIvFzLrqhaSAL3m7EZk8bdZRd3nrrJ-qioUhoCVEsQAvD_BwE https://www.revisionskincare.co.uk/products/c-correcting-complex-30?gad_source=1&gclid=CjwKCAjw7oeqBhBwEiwALyHLM0qGLtVUmk3X_rTk_tLIvFzLrqhaSAL3m7EZk8bdZRd3nrrJ-qioUhoCVEsQAvD_BwE https://www.neostrata.com/products/aging/tri-therapy-lifting-serum/F30159XA.html https://www.skinbetter.com/shop-skincare/product-category/anti-aging/alpharet-overnight-cream-M001.html https://www.skinbetter.com/shop-skincare/product-category/eye-care/eyemax-alpharet-overnight-cream-M009.html https://www.revisionskincare.co.uk/collections/treat-neck/products/nectifirm-advanced https://mederbeauty.com/collections/sheet-masks https://mederbeauty.com/products/enzy-peel-double-action-exfoliating-mask?_pos=2&_sid=4094c872b&_ss=r&variant=44619262263570 The alternatives to injectables: https://mederbeauty.com/products/myo-fix-concentrate?variant=44619261870354 https://revisionskincare.com/products/revox%E2%84%A2-line-relaxer-0-68-fl-oz https://www.skinbetter.com/shop-skincare/product-category/anti-aging/interfuse-intensive-treatment-lines-M005.html The content in this podcast is for general information purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast.

Dr. Sophie Shotter Dr. Sophie and Fiona discuss: • LED masks – in-clinic versus at-home (and the data) • Sophie’s preferred at-home option • Different LED lights and what they do • The Dermalux Flex • LED hype v LED data • Budget options for LED • At home microcurrent devices • What microcurrent can and can’t do • Taking a multi-pronged approach with gadgets and injectables • Radiofrequency – at home versus in-clinic • The Body Balancer – and cellulite • Budget options • Jade rollers, gua sha, ice wands, rollers • Lymphatic drainage massage (and a recommendation) • Body brushing and bamboo tappers • Buccal massage • Micro-needling at home? • The cult behind of the Clarisonic • The skin’s microbiome • Dr Sophie’s recommendations Find out more by heading to https://drsophieshotter.com/ Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en This podcast was produced by https://thepodcastpeople.co/ Dr Sophie and Fiona mention a few brands, ideas, and individuals – all the links are here: https://dermaluxled.com/device/flex-md/ https://www.lustreclearskin.com/ https://www.newabeauty.co.uk/products/newa-starter-kit https://bodyballancer.co.uk/ https://www.charlottetilbury.com/uk/product/cryo-recovery-face-mask https://dimple-amani.com/ https://dimple-amani.com/products/kansa-wand The content in this podcast is for general information purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast.

Dr. Sophie Shotter Dr Sophie and Fiona discuss: • Collagen – a simple explainer • The different types of collagen • The real impact of collagen loss • How stress impacts collagen production (see links below) • What type of collagen should we use? • Dosage information and guidance • Brand recommendations • Hydrolysed collagen • Sources • Is vegan collagen a thing? • The role of vitamin C • Injectables • Other recommendations • Collagen banking • What you can do in-clinic • How long before you'll start seeing results? • When to take collagen • Can pregnant women take it? • Men and collagen • Face creams Find out more by heading to https://drsophieshotter.com/ Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en This podcast was produced by https://thepodcastpeople.co/ Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here: An independent study from 2019 that found collagen supplements do show promise in terms of improving skin elasticity and dermal collagen density > https://jddonline.com/articles/dermatology/S1545961619P0009X More from Dr Sophie on collagen > https://www.getthegloss.com/beauty/collagen-supplements-how-to-know-your-collagen-burn-rate Dr Sophie’s recommendations: https://evernutri.com/products/evercol https://www.absolutecollagen.com/ https://feelingenious.com/ https://www.altrient.com/liposomal-vitamin-c https://www.doseandco.com/uk This is the collagen that’s only available through nutritionists (with a type 2) https://evernutri.com/products/omnicol%E2%84%A21-10-hydrolysed-collagen TO BUY, PLEASE USE THIS CODE: SophieSREvernutri The content in this podcast is for general information purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast.

Dr Sophie Shotter Dr Sophie and Fiona discuss: • Biohacking – an explainer • What’s evidence-based (or not)? • The role of influencers versus expert knowledge • Light therapy (infrared / LED) • Collagen supplements • Clean beauty • Micro needling • Oxygen therapy / hyperbaric oxygen • Skin cell therapy • Oestrogen • IV vitamin C and long COVID • NAD+ (brand linked in below) • Sleep • Vitamin D3 • Magnesium • Oura Ring (linked in below) • Glucose monitoring • Meditation • Nutrition and alcohol • Forest bathing • Fasting and Dr Mindy Peltz / John Hopkins (linked in below) • Perimenopause • Cryotherapy • Home DNA analysis • The Dutch test Find out more by heading to https://drsophieshotter.com/ Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en This podcast was produced by https://thepodcastpeople.co/ Dr Sophie and Fiona mention a few brands, ideas and individuals – all the links are here: https://nuchido.com/pages/nad-supplements https://ouraring.com/ https://drmindypelz.com/ https://www.hopkinsmedicine.org/health/wellness-and-prevention/intermittent-fasting-what-is-it-and-how-does-it-work The content in this podcast is for general informational purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast.

Dr Sophie Shotter Dr Sophie and Fiona discuss: • Health span over life span • How to measure your biological age (link below) • The longevity discussion in-clinic • Adjacent positive impacts of exercise • Good sleep hygiene • Dr Sophie’s evening routine… • … and supplements • Vitamin C’s link to collagen production (research below) • NAD+ • Magnesium • Vitamin D3 • Omega 3’s, inflammation and cognitive function (study below) • Vegan options with omega oils • Resveratrol • Metformin (details of study below) • Spermidine - and autophagy (brand linked in below) • Gut health and skincare (study below) • We can intervene in the ageing process (see Dr David A Sinclair site below) • Epigenetics • DNA tests that calculate our biological age • Telomeres – an explainer • Mental health and micro dosing (TED talk linked in below) • Meditation • Dr. Joe Dispenza (info below) Find out more by heading to https://drsophieshotter.com/ Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en This podcast was produced by https://thepodcastpeople.co/ Dr Sophie and Fiona mention a few brands, ideas and individuals – all the links are here: The link between vitamin C and collagen https://lpi.oregonstate.edu/mic/health-disease/skin-health/vitamin-C#:~:text=Specifically%2C%20vitamin%20C%20has%20been,response%20to%20photodamage%20(48) The link between omega 3’s, mood, and cognitive function https://bmjopen.bmj.com/content/9/6/e027167 Metformin https://fortune.com/well/2023/05/04/metformin-anti-aging-longevity-risks-side-effects/ Spermidine supplement https://oxfordhealthspan.com/#:~:text=Recommended%20by%20world%2Dleading%20longevity,concentrated%20Japanese%20wheat%20germ%20extract. The link between gut health and good skin https://www.sciencedirect.com/science/article/pii/S2352647515000155 Bio Kult probiotics https://www.bio-kult.com/ Symprove probiotic https://www.symprove.com/ Read about Dr David A Sinclair’s work https://lifespanbook.com/ Test your biological age https://glycanage.com/ ‘Why We Sleep’ by Matthew Walker https://www.waterstones.com/book/why-we-sleep/matthew-walker/9780141983769 TED talk on microdosing https://youtu.be/vQuuY9xmzjg?si=k85jak3T2YQW02PU Michael Pollan's How to Change Your Mind https://michaelpollan.com/books/how-to-change-your-mind-uk/#:~:text=%E2%80%9CHow%20to%20Change%20Your%20Mind%E2%80%9D%20is%20a%20calm%20survey%20of,%2Dreporting%2C%20a%20giant%20square. Dr Joe Dispenza https://drjoedispenza.com/ The content in this podcast is for general informational purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast.

Conversations with the award-winning Dr Sophie Shotter covering the latest trends and developments in skincare, longevity, and aesthetics - bringing a science-based approach, and a focus on inner health and wellness.