Hormones, Metabolism & You!

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if brain fog, bloating, exhaustion, and hormonal chaos are not separate problems, but signals of one shared root issue? In this episode of Hormones, Metabolism, and You, Dr. Cassie Smith is joined by returning guest Dr. Shivani Gupta, Ayurvedic practitioner, turmeric researcher, and author of The Inflammation Code. Together, they explore how chronic inflammation quietly disrupts gut health, hormone metabolism, sleep, mood, and energy, especially during perimenopause and menopause. Dr. Gupta explains how ancient Ayurvedic principles align with modern functional medicine, offering practical, non-diet strategies to support digestion, estrogen metabolism, circadian rhythms, and nervous system balance. This conversation focuses on working with the body rather than against it, using daily rhythms, simple rituals, and gut-forward practices to support long-term resilience at every stage of life. Key Topics Covered How chronic inflammation can drive brain fog, bloating, fatigue, and hormonal symptoms The gut–hormone axis and why digestion is central to estrogen metabolism and mood Ayurvedic “digestive fire” (agni) and how modern habits weaken it Why perimenopause and menopause represent a Vata (air and ether) phase of life Early signs of hormonal transition beyond hot flashes, including anxiety, dryness, and sleep disruption How circadian rhythms influence inflammation, hormone balance, and metabolic health Food-first strategies to support estrogen metabolism and reduce bloating Why how and when you eat may matter as much as what you eat The role of gut testing and microbiome balance in long-term healing Super spices as medicine: turmeric, ginger, cumin, coriander, and fennel Why healing does not require extreme diets or rigid routines Building personalized, sustainable self-care rituals that actually stick Key Takeaways Chronic inflammation often connects gut symptoms, hormone imbalance, fatigue, and brain fog Perimenopause and menopause represent a natural shift that requires more grounding and rhythm, not more pushing Gut health plays a central role in estrogen metabolism, mood, and overall resilience Circadian alignment supports inflammation reduction and nervous system balance Small, consistent rituals are often more powerful than complex protocols Spices like turmeric and ginger can support digestion and inflammation when used consistently Healing is individualized and works best when aligned with your body’s natural rhythms Resources & Links 🌐 Website: https://www.shivanigupta.com 📘 Book: The Inflammation Code (Hay House, February 2026)https://www.theinflammationcode.com 🎙️ Fusionary Health Podcast 📲 Instagram: https://instagram.com/dr.shivanigupta 📘 Facebook: https://www.facebook.com/theshivanigupta ▶️ YouTube: https://www.youtube.com/@dr.shivanigupta 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< Doing Everything Right but Still Not Losing Weight? - The Shocking Truth About Midlife Metabolism - Learn How Hormones and Peptides Can Finally Unlock Fat Loss Without More Willpower If you feel like you are eating clean, working out, staying consistent, and your body still will not respond, you are not alone. In this episode, Dr. Cassie Smith sits down with Dr. Aleksandra Gajer, M.D., to explore why weight loss resistance often shows up in midlife and why it is rarely about willpower. They unpack how hormones, sleep, stress, inflammation, and insulin resistance can combine to slow progress, and how peptides can be used as strategic tools when they are properly prescribed, sourced, and monitored. You will also hear a practical breakdown of peptide categories, plus an important safety conversation about avoiding online sourcing and quick clinic prescribing. Key Topics Covered Why traditional dieting often fails for high achieving women in midlife How shifting hormones can influence insulin resistance, metabolism, and body composition The role inflammation can play in fatigue, weight gain, and brain fog Why real food fundamentals still matter even with advanced therapies What peptides are and how they differ from typical medications in the body A simple framework: five peptide categories used in clinical practice Metabolic peptides: GLP 1 therapies, MOTS c, and growth hormone promoting peptides Recovery and inflammation peptides: BPC 157 and the use of KPV for gut and immune balance Cognitive peptides discussed: Selank and Semax, plus sleep support with DSIP Longevity focused peptides: Epitalon, plus discussion of NAD and SS 31 Aesthetic peptide overview: GHK Cu and why formulation and tolerability matter Why peptide stacks can be less effective and harder to troubleshoot The importance of medical oversight, safe sourcing, and individualized dosing Free lever for better health: sleep and boundaries around screens Connect with Dr. Aleksandra Gajer, M.D Website: https://thegajerpractice.com/ LinkedIn: https://www.linkedin.com/in/aleksandra-gajer-md/ 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if your lingering thyroid and hormone symptoms aren’t a lab problem at all, but a gut inflammation issue hiding beneath “normal” results? In this episode of Hormones, Metabolism, and You, Dr. Cassie Smith sits down with holistic nutritionist and physician consultant Josh Dech to explore a core idea many patients never hear: your thyroid and hormone symptoms may be driven by hidden gut inflammation, even when labs look “normal.” Josh explains how gut dysfunction can interfere with hormone signaling, disrupt metabolism, and fuel chronic fatigue, brain fog, and stubborn symptoms. They also discuss common root drivers like toxins, infections, nutrient deficiencies, poor sleep, and chronic stress, plus practical steps to support healing without extreme protocols. Key Topics Covered Why thyroid and hormone symptoms can persist even with “normal” lab results How gut inflammation can block hormone signaling and contribute to fatigue and brain fog Gut health on a spectrum: from mild symptoms to severe inflammatory conditions The “why” behind symptoms vs. labels and diagnoses Mold and environmental exposures as potential hidden drivers for some people The “three buckets” framework: toxins, microbes, and deficiencies The role of sleep, stress, and lifestyle in gut and immune function Why some “healthy” foods can still be personal triggers for certain individuals Supporting drainage and detox pathways as part of recovery Simple, sustainable steps for improving gut and overall health About the Guest Josh Dech is a Holistic Nutritionist and Physician Consultant specializing in Crohn’s disease, ulcerative colitis, and severe IBS. He is known for helping reverse over 400 cases of Crohn’s and colitis through a root-cause, holistic approach to gut health, conditions long considered irreversible within conventional care. Josh has worked alongside some of the world’s most respected medical professionals and has become a trusted educator in the field of digestive and autoimmune health. He hosts a globally ranked top 2 percent podcast, has appeared on international television, and currently serves as a medical lecturer for Priority Health Academy. Today, Josh focuses on educating both physicians and the public on integrative, evidence-informed strategies for healing chronic digestive diseases and restoring long-term gut health. Connect with Josh Dech Facebook: https://www.facebook.com/JoshDechInstagram: https://www.instagram.com/joshdech.health/YouTube: https://www.youtube.com/@joshdech 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if weight loss isn’t about discipline, motivation, or trying harder, but about understanding what your hormones are actually doing? In this powerful New Year mash-up episode of Hormones, Metabolism, and You, Dr. Cassie Smith brings together the most impactful insights from three standout conversations to explain why traditional diets fail so many women and what truly supports sustainable weight loss. Drawing from expert guidance by Tamar Samuels, Shana Hussin, and Terri DeNeui, this episode reframes weight gain as a hormonal and metabolic signal, not a personal failure. Listeners will learn how stress, gut health, insulin resistance, PCOS, thyroid dysfunction, and age-related hormone shifts quietly sabotage fat loss, and why fasting, restriction, and one-size-fits-all diets often make things worse. This episode is especially for women in their 30s, 40s, and 50s who feel stuck, exhausted, and frustrated despite doing “all the right things.” Episode Highlights Why weight gain is often driven by hormones, not willpower How cortisol, leptin, insulin, and thyroid hormones block fat loss What really changes hormonally in your 30s, 40s, and 50s Why testosterone and progesterone decline earlier than most women realize The truth about fasting and why it backfires for stressed women How gut health directly affects metabolism and hormone balance Why PCOS, thyroid issues, and insulin resistance require targeted nutrition How restrictive diets and under-eating damage hormones long term Why protein needs increase with age and how much women actually need Why the scale lies and what markers matter more than weight Key Topics Covered It’s Not Your Fault: Understanding Hormone Shifts Hormonal changes begin earlier than menopause Testosterone loss affects muscle, mood, metabolism, and energy Progesterone decline impacts sleep, stress tolerance, and fat storage Weight gain is often a biological response, not a behavior issue The Hidden Conditions Blocking Weight Loss PCOS, thyroid dysfunction, and insulin resistance explained simply How cortisol and chronic stress stop fat burning Why leptin resistance develops from dieting and fasting Why blood sugar balance matters more than calorie counting Food as Medicine, Not Punishment Why personalized nutrition beats rigid diet rules Protein targets for women as they age The real role of carbs and fats in hormone health Why meal timing and eating enough matters Lifestyle Changes That Actually Work Circadian rhythm alignment and stress reduction Gut health as the foundation of hormone metabolism Why extreme fasting, overtraining, and restriction do harm Root-cause care vs symptom suppression Final Takeaway This New Year, the answer isn’t another diet, cleanse, or restriction plan. Sustainable weight loss happens when you: Support your hormones Heal your gut Eat enough of the right foods Reduce stress Stop fighting your biology Your body isn’t broken. It’s communicating. 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if your hormone symptoms aren’t a hormone problem at all, but warning signs of deeper toxic, gut, and immune stress your body has been carrying for years? In this powerful episode of Hormones Metabolism in You, Dr. Cassie Smith sits down with Dr. Kelly K. McCann, MD, to unpack why hormone symptoms like fatigue, weight gain, brain fog, mood changes, and stubborn metabolic dysfunction are often not hormone problems at all. Instead, Dr. McCann explains how these symptoms are signals pointing to deeper root causes such as environmental toxin exposure, mold, gut dysfunction, immune dysregulation, and chronic inflammation. Together, they challenge the conventional approach of treating hormones in isolation and highlight why normal lab results do not always mean the body is functioning optimally. This conversation explores how everyday exposures from water contamination and plastics to non-stick cookware, pesticides, and personal care products can silently disrupt thyroid function, metabolism, and hormone signaling. The episode also dives into the critical gut hormone immune connection, mold related illness, nutrient depletion, mitochondrial dysfunction, and the concept of the cell danger response. About the Guest Dr. Kelly K. McCann, MD is a board certified physician trained in internal medicine and pediatrics, with advanced training in integrative and functional medicine. Her work focuses on the impact of environmental exposures on human health, including mold illness, chemical toxicity, chronic infections, immune dysregulation, and mast cell activation syndrome. Dr. McCann specializes in treating complex chronic illness by addressing root causes such as toxic burden, gut permeability, mitochondrial dysfunction, and nervous system imbalance. She is the founder of The Spring Center in Southern California and provides care to patients across multiple states. She also teaches and writes extensively on the intersection of environment, immunity, hormones, and healing. Key Topics Covered Why hormone symptoms are messengers, not the root problem Environmental toxins and their impact on thyroid and hormone signaling Mold exposure and its role in chronic illness and metabolic dysfunction The gut hormone immune axis and why gut health is inseparable from hormone health How plastics, PFAS, pesticides, and contaminated water disrupt endocrine function Food related mold and toxin exposure, including grains, corn, and peanuts Heavy metals, mercury accumulation, and bioaccumulation in the body Why many patients struggle despite “normal” lab results Critical labs often missed in conventional care, including thyroid conversion markers The role of mitochondrial dysfunction and the cell danger response Chronic stress, trauma, and nervous system dysregulation in hormone imbalance Why perimenopause often reveals accumulated toxic burden Small, practical steps to reduce toxic load and support healing Links & Resources:  Dr. Kelly K. McCann, MD 🔗 Official Websitehttps://drkellymccann.com/ 🔗 The Spring Centerhttps://thespringcenter.com/ 🔗 LinkedIn Profilehttps://www.linkedin.com/in/dr-kelly-mccann/ 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if many hormone, thyroid, and energy problems come down to a single overlooked molecule your body is quietly running out of? In this episode of Hormones Metabolism in You, Dr. Cassie Smith sits down with nitric oxide expert Dr. Nathan Bryan to explore why nitric oxide is one of the most overlooked yet essential molecules in human health. Together, they unpack nitric oxide’s powerful role in hormone signaling, thyroid function, gut motility, immune defense, blood flow, and mitochondrial energy production. Dr. Bryan explains how nitric oxide deficiency can contribute to fatigue, hormone resistance, insulin resistance, poor circulation, and chronic inflammation, even when labs appear “normal.” They also discuss how modern lifestyle factors such as aging, chronic stress, poor diet, fluoride exposure, antiseptic mouthwash use, and long term antacid use can significantly impair nitric oxide production. Most importantly, this conversation offers practical, science backed strategies listeners can apply immediately to support nitric oxide levels and improve overall hormone health, energy, and longevity. About the Guest Dr. Nathan Bryan holds a Bachelor of Science in Biochemistry from the University of Texas at Austin and earned his doctoral degree from Louisiana State University School of Medicine in Shreveport, where he received the Dean’s Award for Excellence in Research. He completed postdoctoral training as a Kirschstein Fellow at Boston University School of Medicine in the Whitaker Cardiovascular Institute. In 2006, Dr. Bryan joined the faculty at the University of Texas Health Science Center at Houston under the recruitment of Nobel Laureate Dr. Ferid Murad. With over two decades of experience in nitric oxide research, he has made significant contributions to the field, resulting in numerous US and international patents and clinically impactful technologies. Dr. Bryan is also a successful entrepreneur and Founder and CEO of Nitric Oxide Innovations, LLC, where he continues to advance nitric oxide based therapies and molecular medicine worldwide. Key Topics Covered What nitric oxide is and why it is essential for human health How nitric oxide influences hormone signaling and receptor sensitivity The connection between nitric oxide and thyroid function Nitric oxide’s role in gut motility, digestion, and the oral microbiome How nitric oxide supports immune defense and inflammation control Mitochondrial energy production and cellular oxygen delivery Why nitric oxide production declines with age How stress, poor diet, and environmental exposures impair nitric oxide The impact of fluoride, antiseptic mouthwash, and antacids on nitric oxide production Common symptoms associated with nitric oxide deficiency How impaired blood flow affects hormone delivery and tissue response Links & Resources Website: https://drnathansbryan.com/LinkedIn: https://www.linkedin.com/in/drnathansbryan Nitric Oxide Education:https://www.n1o1.com/https://www.no2u.com/https://www.nitricoxideinnovations.com/ Shop N1O1 Products: https://www.awin1.com/cread.php?awinmid=115399&awinaffid=2702698 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if the biggest problem in modern medicine isn’t a lack of treatments, but a lack of training in nutrition, gut health, and root cause care? In this episode, Dr. Cassie Smith welcomes back Dr. Johnny Hadac, now a family medicine resident, to reflect on how his medical training has evolved and where traditional healthcare continues to fall short. Together, they unpack the realities of residency, the lack of meaningful nutrition and gut health education in medical training, and why chronic disease cannot be solved without addressing inflammation, hormones, and the gut. Dr. Hadac shares what he has learned during his first months of residency, how functional medicine principles have shaped his approach to patient care, and why proactive, relationship based medicine leads to better outcomes. The conversation also explores the broken insurance driven healthcare system, the importance of provider education, and how social media can help close the knowledge gap. They also dive into Dr. Hadac’s bestselling cookbook, which combines practical, affordable recipes with extensive education on gut health, insulin resistance, fiber, and hormone balance. This episode offers hope for the future of medicine and practical tools for patients and providers alike. About the Guest Dr. Johnny Hadac is a family medicine resident, physician, certified nutritionist, and culinary medicine specialist. He is the founder of Total Weight Loss and Muscle Dummies, a global health community with over two million followers focused on affordable, science based nutrition and lifestyle habits. Dr. Hadac is a bestselling cookbook author and app developer who blends medical science with real world practicality. His work centers on gut health, insulin resistance, metabolic health, and sustainable weight loss through high fiber, high protein, whole food nutrition. Through social media, education, and clinical practice, he is helping reshape how people understand health, food, and disease prevention. Key Topics Covered What residency is really like and how medical education is evolving Major gaps in nutrition and gut health training for physicians Why gut health is foundational to hormone balance and chronic disease The role of fiber, fermented foods, and inflammation in metabolic health How functional medicine principles improve patient outcomes Challenges of insurance driven healthcare systems Direct primary care and proactive medicine models Social media as a tool for patient and provider education Insulin resistance and metabolic dysfunction Practical, accessible nutrition strategies for long term health Connect with Dr. Johnny Hadac LinkedIn: https://www.linkedin.com/in/johnny-hadac-6a38aa126/Instagram: https://www.instagram.com/drjohnnyhadac/ 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if the biggest breakthrough in women’s health this decade is the long overdue reversal of a warning that never should have existed in the first place? In this timely episode, Dr. Cassie Smith sits down with hormone expert and healthcare reform advocate Dr. Terri DeNeui, DNP, APRN, ACNP-BC to unpack the FDA’s landmark decision to remove the black box warning from estrogen containing HRT. For the first time in over twenty years, science and policy finally align, creating safer and more accessible options for millions of women. Dr. Cassie and Dr. Terri break down what the original research actually showed, how estrogen became unfairly feared, and why the updated guidelines are long overdue. They explore the benefits of estrogen, progesterone, and testosterone for women, clearing up misconceptions and highlighting the need for better hormone education among providers and patients. With clinical insights and decades of experience, this episode reveals the truth about hormone therapy, why women have suffered needlessly for two decades, and how the removal of the black box warning can reshape the future of women's health.   About the Guest Dr. Terri DeNeui, DNP, APRN, ACNP-BC is a board certified Adult Acute Care Nurse Practitioner, entrepreneur, Chief Science Officer, and leading voice in healthcare reform. She serves on the Executive Committee of the America First Policy Institute and the America First Women’s Initiative, contributing to national healthcare policy. A Summa Cum Laude graduate of the University of Texas at Arlington, Dr. DeNeui holds the Doctor of Nursing Practice degree. She is the Founder of EVEXIAS Medical Centers and EVEXIAS Health Solutions, and creator of the EvexiPEL Method of hormone optimization, used globally and supported by outcomes research. She is also lead teaching faculty for the A4M World Congress on Anti Aging Medicine. Her published work includes the peer reviewed article Best Practices in Care for the Menopausal Patient and the bestselling book Hormone Havoc: Dispelling the Myths and Misconceptions about Hormones in Women and Men.   Key Topics Covered What the FDA’s black box removal means for women How the Women’s Health Initiative was misinterpreted Estrogen’s role in brain, heart, bone, gut, metabolic, and vaginal health How fear based messaging led to unnecessary suffering Benefits and safety of micronized progesterone Why testosterone is essential for women’s mood, libido, muscle, and cognition Early testosterone decline and how it affects daily life Hormones, intimacy, and relationship well being Why hormone therapy requires gut health evaluation and individualized dosing Provider education gaps and self advocacy for women Recognizing hormone decline across the lifespan Why better policy and access to hormone therapy are urgently needed Connect with Dr. Terri DeNeui Instagram: https://www.instagram.com/drterrideneui/ Facebook: https://www.facebook.com/DrTerriDeNeui/LinkedIn: https://www.linkedin.com/in/terri-deneuiWebsite: https://www.evexias.comPodcast: https://podcasts.apple.com/us/podcast/the-dr-terri-show/id1757438909Email: terri.deneui@evexias.com Phone: (214) 202-4727 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if the key to reversing Graves disease starts with uncovering the hidden triggers your thyroid has been reacting to all along? In this information rich episode, Dr. Cassie Smith sits down with functional medicine practitioner and thyroid expert Dr. Eric Osansky to break down the realities of Graves disease and hyperthyroidism. They explore why diagnosis is often delayed, what truly drives autoimmune thyroid conditions, and how gut health, nutrient deficiencies, infections, stress, and environmental toxins all influence thyroid function. Dr. Osansky also shares his personal remission journey and offers practical guidance, testing recommendations, and natural treatment options. This episode is essential for anyone navigating Graves disease, hyperthyroidism, or persistent thyroid symptoms and searching for a root cause approach. About the Guest Dr. Eric Osansky is a functional medicine practitioner with more than 15 years of clinical experience in chiropractic care, nutrition, and autoimmune thyroid health. After reversing his own Graves disease in 2009, he dedicated his career to helping others heal naturally. He is the author of Natural Treatment Solutions for Hyperthyroidism and Graves Disease, Hashimoto’s Triggers, and The Hyperthyroid Healing Diet, and hosts the Save My Thyroid podcast. He holds a Master’s degree in Human Nutrition and Functional Medicine and advanced certifications in nutrition and herbal therapy. Key Topics Covered How Graves disease differs from hypothyroidism and why hyperthyroidism is often misunderstood The environmental, immune, and lifestyle triggers that drive autoimmune thyroid disease Stress, infections, toxins, and overtraining as common contributors How gluten, corn, dairy, and high sodium intake influence leaky gut and autoimmunity The thyroid gut connection and how dysbiosis, H. pylori, and nutrient malabsorption affect thyroid function Essential nutrients for healthy thyroid hormone production and conversion The most important labs thyroid patients should request How H. pylori, viruses, mold, and stealth infections impact autoimmunity Conventional treatments including methimazole, PTU, beta blockers, and when they are necessary Natural therapies such as bugleweed, motherwort, lemon balm, selenium, and L carnitine The role of LDN and why results vary in Graves disease Why healing requires sleep, stress management, gut repair, movement, and nutrient optimization How to advocate for your health when providers overlook root causes Connect with Dr. Eric Osansky Facebook: https://www.facebook.com/NaturalThyroidTreatment/YouTube: https://www.youtube.com/@NaturalThyroidDoctorInstagram: https://www.instagram.com/drericosansky/Website: https://savemythyroid.com 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠

>>Join our FREE monthly Gut Health Webinar, so you can begin your Healing Journey.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠https://modernendocrinewellness.com/join-gut-health⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠<< What if the real answers to your midlife hormone struggles are not in a pill, but in understanding the deeper connections between your thyroid, metabolism, and the way your body changes over time? In this powerhouse mashup episode, Dr. Cassie Smith brings together two of the most outspoken and experienced voices in functional medicine: McCall McPherson, thyroid expert and founder of Modern Thyroid Clinic, and Dr. Tyna Moore, a naturopathic physician and metabolic health disruptor. Together, they unpack the complex hormonal shifts women experience—especially during perimenopause and menopause—and share real-world strategies to reclaim health, energy, and vitality. From GLP-1 medications to progesterone deficiency, thyroid misdiagnosis to strength training, this episode covers the most pressing questions women are asking today. You’ll hear personal insights, clinical wisdom, and evidence-based tools for navigating hormone changes, gut issues, inflammation, and mental health with clarity and confidence. 👤 About the Guests McCall McPherson is the founder of Modern Thyroid Clinic and Thyroid Nation, a TEDx speaker, physician assistant, and a thyroid warrior herself. Her mission is to end the suffering of millions with thyroid disorders through expert care, patient advocacy, and empowering education. Dr. Tyna Moore is a licensed Naturopathic Physician and Chiropractor specializing in resilient metabolic health, regenerative medicine, and clinical strength training. She's also the host of The Dr. Tyna Show and a strong advocate for women’s health and muscle-centric aging. 🔑 Key Topics Covered ✅ The truth about GLP-1s like semaglutide and tirzepatide—and what microdosing really means ✅ When to consider hormone therapy and why most women need progesterone earlier than expected ✅ Why muscle is your best metabolic and hormone-supporting organ ✅ The thyroid–estrogen connection and how hormone shifts during menopause impact thyroid function ✅ How GLP-1s can expose hidden dysfunctions like gut dysbiosis and low estrogen ✅ Why low progesterone may be behind your irritability, sleep issues, and anxiety ✅ The importance of comprehensive thyroid testing (FT3, FT4, RT3) and individualized care ✅ Gut–hormone–brain axis: how estrogen and thyroid hormones influence mood and digestion ✅ Alcohol and inflammation: the honest truth about even “just one glass” ✅ Empowering women to advocate for their health in a broken system ✅ The generational shift in how women approach midlife and aging 📲 Follow Dr. Cassie Smith & Modern Endocrine 💻 Website:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modern-endocrine.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📸 Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.instagram.com/modernendocrine_/⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🌟 Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.facebook.com/ModernEndocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📽️ YouTube:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.youtube.com/@modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠ 🕹️ TikTok:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.tiktok.com/@modernendocrine?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠ 📰 Newsletter:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://linktr.ee/modernendocrine⁠⁠⁠⁠⁠⁠⁠⁠⁠ ➡️ Disclaimer:⁠⁠⁠⁠⁠⁠⁠⁠⁠ https://www.modernendocrineokc.com/disclaimer-6353⁠