The Neuro Experience

Louisa Nicola & Pursuit Network
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Dec 17, 2020 • 51min

132: Optimising Health Instead of Fixing Sickness | Dr. Molly Maloof, MD

This week on The Neuro Experience podcast I speak with Dr. Molly Maloof on blood sugar, hormones, self biohacking with labs and imaging and the importance of stress-relieving recovery practices.We also get into Glucose Monitoring, Mitochondrial Stress, & Mental Health. During the episode, Molly goes into discussing 'what is health' and what is 'sickness'? The old definition of health is that it is a static state. Molly is on a mission to radically extend healthspan, maximize human potential, and redefine health care using medicine, technology, education, & media. Her fascination with innovation permeates her concierge medical practice that is focused on providing personalized medicine to entrepreneurs, technology executives, investors, & celebrities in Los Angeles and the Bay Area.The new idea of health is the ability to adapt and manage it when faced with adversity! This statement was made abundantly clear throughout the organic conversation that Louisa and Molly have as they delve into the hormonal adaptations of women during their 30's and draws an insight into self diagnosis as a means for longevity - 'know thyself'. Homeostasis vs Allostasis, which is our ability to achieve stability through behavioral change and mental health through the ability of an individual to reach their potential, cope with stressors and contribute to their community.The key to healthy aging by fundamentally building bioenergetic capacity by building mitochondria, essentially our power plants. Find Molly here: https://drmolly.co/and https://www.instagram.com/drmolly.co/The Neuro Athletics Newsletter Instagram: @louisanicola_Twitter : @louisanicola_YouTube: @Louisa NicolaThe Neuro Experience Podcast is proud to have hosted: Dr Andrew Huberman, Dr Gabrielle Lyon, Dr Layne Norton, Thomas DeLauer, Shawn Stevenson, Dr. Rocio Salas-Whalen, Saad Alam, Uma Naidoo, Dr. Lanna Cheuck, Angela Lee Pucci, Jillian Turecki, Dr. Jordan Feigenbaum, Dr. Darren Candow, Dr. Sue Varma, Evy Poumpouras, Dr Casey Means, Renee Deehan, Dr Chris Palmer, Dr Charles Brenner, Dr Joe Zundell, Dr Ray Dorsy, Dr Dale Bredeson, Dr. Ben Bikman Learn more about your ad choices. Visit megaphone.fm/adchoices
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Dec 2, 2020 • 46min

131: How Your Gut is Speaking With Your Brain | Dr. Azza Gadir, PhD

There's a community of 38,000,000,000,000 microorganisms (mostly bacteria) living in and on us. Seeded by our mothers, this is our microbiome—our non-human half we can’t live without. In an astonishing journey of symbiosis, microbes co-evolved with us, carrying in their genes, and therefore in us, the entire history of the world.The gut. Microbiome. Microbiota. Probiotics, probiotics. What on earth are these words and how do they affect the brain? We have all heard of the gut brain axis. I know I see the word being thrown around and it’s almost impossible to not want to know more about it. This subject has always been a mystery to me because like you will learn in this episode, the microbiome is an entire universe. It takes so much knowledge and time to really understand it and it’s relation to our lives and our health. So in order to understand this fully and in more depth I recruited the amazing Dr. Azza Gadir to the neuro experience to explore the depths of microbiome with us. Azza is an immunologist who completed her postdoctoral training in the laboratory at Harvard Medical School where her published research was focused on the immunological mechanisms that underlie the role of the gut microbiome in conferring protection to diseases early in life. For this work, she holds issued and pending patents and has collaborated with industry partners to accelerate the discovery of microbiome-related immunotherapies for food allergy.She is also the head of research and development at Seed. If you haven’t checked them out please do so on Instagram and you will be just as inspired as me when you see their work of art literally coming to life on your phone. Seed is an ecosystem of scientists, doctors, innovators, entrepreneurs, and translational storytellers from around the world. Who collectively believe in the potential of the microbiome to improve human and planetary health. Together, they're raising the bar in bacteria.In this episode you will learn:  What is the microbiome and how does it play a role in our BrainHealth  Azza Gadir’s career from start to finish- how women in science are shaping the world What is the immune system and the ‘gut microbiome’  The link between neurodegenerative disease and the gut microbiome  What is B12 deficiency and is it related to the gut microbiome?  How can we impact the function of our microbiome  What is the ‘gut-brain axis’ and the link between mental health and gut bacteria Best diet to eat for a health microbiome  How to protect your gut throughout the lifespan  REVIEW/SHARE:If you enjoyed the episode and have a spare 1-2 minutes please leave a review on iTunes so the Neuro Experience podcast ranks higher and becomes more discoverable for other listeners.  Sign up to Louisa's email newsletter: https://bit.ly/37bR58XConnect with Louisa on Instagram: https://bit.ly/2SXPA5MThe Neuro Athletics Newsletter Instagram: @louisanicola_Twitter : @louisanicola_YouTube: @Louisa NicolaThe Neuro Experience Podcast is proud to have hosted: Dr Andrew Huberman, Dr Gabrielle Lyon, Dr Layne Norton, Thomas DeLauer, Shawn Stevenson, Dr. Rocio Salas-Whalen, Saad Alam, Uma Naidoo, Dr. Lanna Cheuck, Angela Lee Pucci, Jillian Turecki, Dr. Jordan Feigenbaum, Dr. Darren Candow, Dr. Sue Varma, Evy Poumpouras, Dr Casey Means, Renee Deehan, Dr Chris Palmer, Dr Charles Brenner, Dr Joe Zundell, Dr Ray Dorsy, Dr Dale Bredeson, Dr. Ben Bikman Learn more about your ad choices. Visit megaphone.fm/adchoices
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Nov 19, 2020 • 1h 9min

130: Take Control Of Your Brain | Dr. David MD and Dr. Austin Perlmutter MD

Our brains have been hijacked. We are now living in a world where we are sickened by our food system, the pandemic and of course our habits. It all starts with a bad night sleep- Getting enough sleep won’t just invigorate you; it could also help control how much you eat. A lack of sleep is linked to overeating—especially the overconsumption of junk food—which can lead to weight gain and increased inflammation.Two hormones that help regulate hunger—ghrelin and leptin—are affected by sleep: Ghrelin stimulates appetite, while leptin decreases it. When the body is sleep-deprived, the level of ghrelin spikes, while the level of leptin falls, leading to an increase in hunger.This cascade of events produces a cycle of bad decisions and the bad decisions lead to frustration, anger, resentment and selfishness. Brain Wash: Detox Your Mind for Clearer Thinking, Deeper Relationships, and Lasting Happiness is co-authored by best-selling author David Perlmutter, MD and Austin Perlmutter, MD.David is a Board-Certified Neurologist and five-time New York Times bestselling author. He serves on the Board of Directors and is a Fellow of the American College of Nutrition. He received his M.D. degree from the University of Miami. Austin is David’s son, who is a board certified internal physician who also graduated from the university of Miami. His academic focus is in understanding the decision-making process, how it is influenced by internal and external factors, and how it changes our health and illness outcomes. Austin, along with David Perlmutter, M.D., is the co-author of the newly released book, Brain Wash. At the beginning of the show David and Austin give a detailed discussion about the science of inflammation from a neural perspective. In this episode we discuss:Neural Inflammation Connection between sleep and increased hunger The Neuroscience of decision making How exercise impacts the brain for the betterWhat is sugar? Where can it be found? What is sugars impact on brain function and cognitive performance?The Ten-Day Brain Wash reset for your brain and body  Where to learn more about Drs. David and Austin Perlmutter Find Austin and David here:Instagram: DavidInstagram: AustinCheck out their book: Brain WashThe Neuro Athletics Newsletter Instagram: @louisanicola_Twitter : @louisanicola_YouTube: @Louisa NicolaThe Neuro Experience Podcast is proud to have hosted: Dr Andrew Huberman, Dr Gabrielle Lyon, Dr Layne Norton, Thomas DeLauer, Shawn Stevenson, Dr. Rocio Salas-Whalen, Saad Alam, Uma Naidoo, Dr. Lanna Cheuck, Angela Lee Pucci, Jillian Turecki, Dr. Jordan Feigenbaum, Dr. Darren Candow, Dr. Sue Varma, Evy Poumpouras, Dr Casey Means, Renee Deehan, Dr Chris Palmer, Dr Charles Brenner, Dr Joe Zundell, Dr Ray Dorsy, Dr Dale Bredeson, Dr. Ben Bikman Learn more about your ad choices. Visit megaphone.fm/adchoices
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Nov 5, 2020 • 1h 11min

129: The Brain's Pharmacist. Learning how to Fight Infections and Fuel the Brain Through Supplementation | Dr. James DiNicolantonio, PharmD

My guest is Dr. James DiNicolantonio who is a cardiovascular research scientist and Doctor of Pharmacy at Saint Luke’s Mid America Heart Institute in Kansas City, Missouri. He is the author of The Salt Fix, Superfuel and his latest book ’The Immunity Fix’. James is  a well-respected and internationally known scientist and expert on health and nutrition, he has contributed extensively to health policy and has even testified in front of the Canadian Senate regarding the harms of added sugars. We start the episode off by talking about the journey of becoming a PharmD and the numerous published articles that James has researched and written. At the beginning of the episode we also begin to discuss:1.Immunology 101—The innate and adaptive immune system.2. Antibodies, B cells—How they fight viruses, create antibodies and T cells—Role in the adaptive immune system and ability to kill infected cells to prevent viral spread. In the middle of the episode we do spend a majority of the time talking about: 1. Latest research and findings on COVID-19 and it’s correlation to metabolic dysfunction, comorbidities and   risk factors associated with worse COVID19 outcomes. Towards the end: 1. Supplementation, nutrition and lifestyle interventions that help boost the immune system in an effort to fight off infections. Thank you to our sponsors:Eight Sleep- use code NEURO at checkoutMUSE- get 10% off - CODE: NEUROYou can find me here:Newsletter: https://bit.ly/3ewI5P0Instagram: thediamondboss_Twitter : louisanicola_Please leave a review on Apple iTunes!REVIEW/SHARE:If you enjoyed the episode and have a spare 1-2 minutes please leave a review on iTunes so the Neuro Experience podcast ranks higher and becomes more discoverable for other listeners.  The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Neuro Experience podcast, its employees, guests and affiliates assume no liability for the application of the information discussed. The Neuro Athletics Newsletter Instagram: @louisanicola_Twitter : @louisanicola_YouTube: @Louisa NicolaThe Neuro Experience Podcast is proud to have hosted: Dr Andrew Huberman, Dr Gabrielle Lyon, Dr Layne Norton, Thomas DeLauer, Shawn Stevenson, Dr. Rocio Salas-Whalen, Saad Alam, Uma Naidoo, Dr. Lanna Cheuck, Angela Lee Pucci, Jillian Turecki, Dr. Jordan Feigenbaum, Dr. Darren Candow, Dr. Sue Varma, Evy Poumpouras, Dr Casey Means, Renee Deehan, Dr Chris Palmer, Dr Charles Brenner, Dr Joe Zundell, Dr Ray Dorsy, Dr Dale Bredeson, Dr. Ben Bikman Learn more about your ad choices. Visit megaphone.fm/adchoices
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Oct 19, 2020 • 1h 36min

128: Advancing Alzheimer's Disease Interventions. Looking at Metabolism, Genotype and Lab Tests | Team Sherzai, MD

Utilizing a strong scientific foundation both through their own research and the research of others, Dr. Dean and Dr. Ayesha Sherzai present a solid case for the reduction of Alzheimer’s disease and other forms of dementia through prevention. Show notes for episode found here: https://bit.ly/2ICAmS3Co-directors of the Brain Health and Alzheimer’s Prevention Program at Loma Linda University Medical Center, Team Sherzai is the dynamic husband and wife duo behind the largest clinical and observational study on Alzheimer’s to date as well as the co-authors of The Alzheimer’s Solution*, a must-read primer that details their extensive research, chronicles the remarkable results they have experienced working with patients first-hand, and sets forth the first ever comprehensive program to prevent Alzheimer’s disease, improve cognitive function, and ultimately optimize long-term brain health.We discuss: 1. Alzheimer's Disease diagnosis and prevention 2.  Genotype (15:40 - 20:40)  APOE-4 gene  Using GWAS to identify alzheimers disease linked genes  Other genes are PEN1, 2 and APP - deterministic genes  Determining your rate of getting AD from your genotype  3. Cognitive testing prior to further diagnosis4. Prevalence of AD in the US and the pathology of AD5. The future of medicine- a personalised approach6. Metabolic dysfunction, CGM and pathways that lead to AD“Food is the single greatest tool we have in the fight against Alzheimer’s.”  Ayesha Sherzai REVIEW/SHARE:If you enjoyed the episode and have a spare 1-2 minutes please leave a review on iTunes so the Neuro Experience podcast ranks higher and becomes more discoverable for other listeners.  Sign up to Louisa's email newsletter: https://bit.ly/37bR58XConnect with Louisa on Instagram: https://bit.ly/2SXPA5MThe Neuro Athletics Newsletter Instagram: @louisanicola_Twitter : @louisanicola_YouTube: @Louisa NicolaThe Neuro Experience Podcast is proud to have hosted: Dr Andrew Huberman, Dr Gabrielle Lyon, Dr Layne Norton, Thomas DeLauer, Shawn Stevenson, Dr. Rocio Salas-Whalen, Saad Alam, Uma Naidoo, Dr. Lanna Cheuck, Angela Lee Pucci, Jillian Turecki, Dr. Jordan Feigenbaum, Dr. Darren Candow, Dr. Sue Varma, Evy Poumpouras, Dr Casey Means, Renee Deehan, Dr Chris Palmer, Dr Charles Brenner, Dr Joe Zundell, Dr Ray Dorsy, Dr Dale Bredeson, Dr. Ben Bikman Learn more about your ad choices. Visit megaphone.fm/adchoices
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Sep 17, 2020 • 1h 5min

127: Decoding the Female Brain. Hormones, Brain Areas that Change Throughout the Lifespan | Dr. Sarah McKay

For women, understanding how the brain works during the key stages of life - in utero, childhood, puberty and adolescence, pregnancy and motherhood, menopause and old age - is essential to their health. Dr Sarah McKay is a neuroscientist who knows everything worth knowing about women's brains, and shares it in this fascinating, essential episode.***EPISODE SHOW NOTES****Understanding how the brain grows and changes through the stages of life is key to health and wellbeing. This is not an episode about the differences between male and female brains, nor a an episode using neuroscience to explain gender-specific behaviours, the 'battle of the sexes' or 'Mars-Venus' stereotypes. This is an episode about what happens inside the brains and bodies of women as they move through the phases of life, and the unique - and often misunderstood - effects of female biology and hormones.Dr McKay gives insights into brain development during infancy, childhood and the teenage years (including the onset of puberty) and also takes a look at mental health as well as the ageing brain. The episode weaves together findings from the research lab, case studies and interviews with neuroscientists and other researchers working in the disciplines of neuroendocrinology, brain development, brain health and ageing.In the episode you will learn specifically about the brain during: 1. Phases of brain changes: Childhood, Puberty, The Menstrual Cycle, The Teenage Brain, Depression and Anxiety, Pregnancy and Motherhood, Menopause, The Ageing Brain2. Structural differences between male and female brains 3. Biggest studies that have been done on the gendered brain 4. What happens in the brain of a male when he is becoming a father? 5. Hormones related to brain change 6. What is brain fog? how to overcome brain fog 7. Are women crazy when they have PMS? What happens to the brain when women are menstruating 8. Neurobiology and evolution of the brain9. How how environment shapes our mind and brain "the meaning we make of our life experiences changes the contexts that we're in"We also have some fun commentary and laughter where I share some personal stories about myself and what it means to be a woman who experiences a crazy surge of hormones once a month. Find more about Sarah here on Instagram. Please send your reviews and comments on this episode onto itunes hereThe Neuro Athletics Newsletter Instagram: @louisanicola_Twitter : @louisanicola_YouTube: @Louisa NicolaThe Neuro Experience Podcast is proud to have hosted: Dr Andrew Huberman, Dr Gabrielle Lyon, Dr Layne Norton, Thomas DeLauer, Shawn Stevenson, Dr. Rocio Salas-Whalen, Saad Alam, Uma Naidoo, Dr. Lanna Cheuck, Angela Lee Pucci, Jillian Turecki, Dr. Jordan Feigenbaum, Dr. Darren Candow, Dr. Sue Varma, Evy Poumpouras, Dr Casey Means, Renee Deehan, Dr Chris Palmer, Dr Charles Brenner, Dr Joe Zundell, Dr Ray Dorsy, Dr Dale Bredeson, Dr. Ben Bikman Learn more about your ad choices. Visit megaphone.fm/adchoices
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Sep 11, 2020 • 1h 27min

126: The Strongest Weapon Against Heart Disease and COVID-19 is Your Immunity | Dr. ASEEM MALHOTRA MD

My guest today is Dr Aseem Malhotra, an NHS Consultant Cardiologist, and visiting Professor of Evidence Based Medicine. He is a world renowned expert in the prevention, diagnosis and management of heart disease.EPISODE SHOW NOTES HEREDr Aseem's passion for writing on and researching various health related issues has resulted in a vast quantity of published academic articles in major medical journals, as well as many other public acknowledgments.So today, As we continue to learn more about #COVID-19, we continue to see a pattern in those more at risk. People who aren’t metabolically healthy (think obesity, type 2 diabetes, cardiovascular disease, and hypertension) are much more likely to experience severe complications if they are to get the virus. And to put that in perspective, only 1 in 8 Americans are considered metabolically healthy. That means a lot of us are at risk during this already alarming time. We can start changing that today, though, and create a newfound health baseline while creating a greater level of resilience when it comes to chronic disease and future situations like this. The #MetabolicSyndrome (MetS) has been called a global epidemic by the WHO1 and is considered a major public health problem, with 34% of Americans over the age of 20 estimated to be affected. Among adolescents, 9.4% are estimated to have MetS and the prevalence rises to 44.2% among those that are obese.MetS is known to affect cognition and raise the risk for dementia which is why I have introduced it twice now on The Neuro Experience podcast. In medicine, and specifically in medical training, there are three types of errors: technical errors, judgmental errors, and normative errors. (Technically, there is a fourth called quasi-normative errors, but we’ll save that for another time.) Dr. Aseem draws on his experience in evidence based medicine and talks to us about making good judgement in medicine. In this episode you will learn:  The five biomarkers of metabolic dysfunction   Dr. Aseem’s personal experience with belly fat and excessive sugar intake Health disparities and COVID-19 outcomes Metabolic disease, excess body fat, and chronic inflammation lead to worse outcomes from COVID-19, as well as from the flu Intermittent fasting and the ketogenic diet Drivers of chronic disease and misery  Evidence based medicine - why doctors need to stay up-to-date and informed  Misinformation in the medical community Dr. Aseem can be found here. Leave a review here. The Neuro Athletics Newsletter Instagram: @louisanicola_Twitter : @louisanicola_YouTube: @Louisa NicolaThe Neuro Experience Podcast is proud to have hosted: Dr Andrew Huberman, Dr Gabrielle Lyon, Dr Layne Norton, Thomas DeLauer, Shawn Stevenson, Dr. Rocio Salas-Whalen, Saad Alam, Uma Naidoo, Dr. Lanna Cheuck, Angela Lee Pucci, Jillian Turecki, Dr. Jordan Feigenbaum, Dr. Darren Candow, Dr. Sue Varma, Evy Poumpouras, Dr Casey Means, Renee Deehan, Dr Chris Palmer, Dr Charles Brenner, Dr Joe Zundell, Dr Ray Dorsy, Dr Dale Bredeson, Dr. Ben Bikman Learn more about your ad choices. Visit megaphone.fm/adchoices
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Sep 4, 2020 • 1h 5min

125: Blood Glucose Decoded: Insulin, Metabolic Dysfunction and Blood Glucose Monitors | DR. CASEY MEANS, MD

Dr. Casey Means, a Stanford-trained medical doctor and co-founder of Levels, explores the intricacies of metabolic health. She discusses hyperinsulinemia and the crucial role of blood glucose stabilization for longevity. The conversation highlights the benefits of continuous glucose monitoring for personal health insights and improved well-being. Casey also examines the impact of diet, exercise, and specific foods like Ceylon cinnamon on insulin sensitivity and metabolic function, advocating for a personalized approach to health.
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Aug 25, 2020 • 53min

124: Smart Drugs, Nootropics and Enhancing Brain Performance | Dr. Greg Kelly

Show notes: https://www.theneuroexperience.com/Promotion: Get a FREE bottle of QUALIA MIND by rating and reviewing the podcast. Nootropic also known as ‘cognitive enhancers’ are drugs that some people use in an attempt to improve memory, increase mental alertness and concentration as well as boost energy levels and wakefulness.There are many different nootropics. Some are pharmaceutical drugs that are designed to treat conditions such as sleepiness or narcolepsy, and to improve attention and focus in people with attention disorders. However, some healthy people use these drugs in an attempt to improve their cognitive performance.We are interviewing Dr. Greg Kelly - Naturopathic physician (N.D.) and lead product formulator at Neurohacker Collective. In this episode you will discover: 1. The history of Nootropics2. Stacking - what nootropics work well together3. How compounds cross the blood brain barrier 4. Mitochondria and brain health 5. Concussions and neuronal insults - do nootropics work? 6. Why would someone take smart drugs? Are they for everyone?7. SLEEP!! What are the best nootropics for enhancing deep sleep? 8. The mushroom family- unlocking your brains potential with lions main and other types of mushrooms 9. Best way to approach your nootropic journey. Neurohacker Collective was founded in 2015 with the mission of creating best in class well-being products by employing a unique methodology to research and development based on complex systems science. This scientific approach focuses on supporting the body’s ability to self-regulate, rather than overriding regulatory systems with chemicals designed to move a biomarker in a particular direction. The company began with a focus on cognitive products with the launch of its Qualia nootropic line and will continue to provide comprehensive products for overall peak performance.Get 15% of Qualia products using code DIAMOND15 at https://bit.ly/3aT5YwIThe Neuro Athletics Newsletter Instagram: @louisanicola_Twitter : @louisanicola_YouTube: @Louisa NicolaThe Neuro Experience Podcast is proud to have hosted: Dr Andrew Huberman, Dr Gabrielle Lyon, Dr Layne Norton, Thomas DeLauer, Shawn Stevenson, Dr. Rocio Salas-Whalen, Saad Alam, Uma Naidoo, Dr. Lanna Cheuck, Angela Lee Pucci, Jillian Turecki, Dr. Jordan Feigenbaum, Dr. Darren Candow, Dr. Sue Varma, Evy Poumpouras, Dr Casey Means, Renee Deehan, Dr Chris Palmer, Dr Charles Brenner, Dr Joe Zundell, Dr Ray Dorsy, Dr Dale Bredeson, Dr. Ben Bikman Learn more about your ad choices. Visit megaphone.fm/adchoices
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Aug 13, 2020 • 43min

123: Upgrade Your Brain With Precision Medicine - Dr. MATTHEW DAWSON MD

The brain may be complex, but there are certainly proven ways to improve brain function. Have you ever heard of genomics and precision medicine? I had Dr. Matthew Dawson on the podcast (episode 111) and we were introduced to the topic of precision medicine and today we are talking all about brain optimisation. Dr. Matt Dawson is a precision medicine physician in Lexington, KY, co-host of the Wild Health Podcast, and has been obsessed with performance optimization as long as he can remember. In this episode you will discover: 1. Matt's work on the frontlines of the COVID-19 pandemic 2. Testing for brain and body function 3. blood glucose and it's relationship with brain health 4. Gut microbiome-how to test and why it's important 5. Longevity- what is it and how can we live longer and healthier 6. The benefits of cold exposure7. Personalised medicine and the future of health 8. How to sign up for the brain Summit hosted by Wild Health You can check out the Wild Health team here: https://wildhealth.com/Their Instagram here: https://www.instagram.com/wildhealthmd/?hl=enDon't forget to leave a review if you are enjoying the show!The Neuro Athletics Newsletter Instagram: @louisanicola_Twitter : @louisanicola_YouTube: @Louisa NicolaThe Neuro Experience Podcast is proud to have hosted: Dr Andrew Huberman, Dr Gabrielle Lyon, Dr Layne Norton, Thomas DeLauer, Shawn Stevenson, Dr. Rocio Salas-Whalen, Saad Alam, Uma Naidoo, Dr. Lanna Cheuck, Angela Lee Pucci, Jillian Turecki, Dr. Jordan Feigenbaum, Dr. Darren Candow, Dr. Sue Varma, Evy Poumpouras, Dr Casey Means, Renee Deehan, Dr Chris Palmer, Dr Charles Brenner, Dr Joe Zundell, Dr Ray Dorsy, Dr Dale Bredeson, Dr. Ben Bikman Learn more about your ad choices. Visit megaphone.fm/adchoices

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