ID:IOTS - Infectious Disease Insight Of Two Specialists

ID:IOTS is 1 year old today! Jame and Callum have a short chat about the the podcast, why we started and where we’re going. Of course, the real ID:IOTS are the friends we made along the way…If you want to send us cake email idiotspodcasting@gmail.comSend us a textSupport the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

Back after a summer break, Jame and Callum discuss the fascinating machine that is the MALDI-TOF. Matrix Assisted Laser Desorption Ionisation Time Of Flight mass spectrometry. We discuss the basics of how it functions, its application in the lab and some pros and cons of its use along with what the future may hold. Here are some relevant videos and papers:- Exciting video of MALDI-TOFhttps://www.youtube.com/watch?v=0jeFpXHZ8W0&ab_channel=BrukerDaltonics- MALDI-TOF to detect MRSA https://www.frontiersin.org/articles/10.3389/fmicb.2020.00232/full- Direct MALDI-TOF on blood cultures https://www.spandidos-publications.com/10.3892/etm.2020.9365- MALDI-TOF to detect CPEhttps://www.frontiersin.org/articles/10.3389/fmicb.2021.789731/full Send us a textSupport the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

Delve into the world of beta-lactamases with discussions on ESBLs, AmpC, and Carbapenemases. Explore classification systems, resistance patterns, and methods of detection. Learn about the challenges of managing CPE carriers and the significance of understanding antibiotic resistance mechanisms.

In the podcast, experts discuss carbapenems - their spectrum, resistance, usage, and side effects. They explore different types like meropenum and imipenum, along with challenges in treating resistant bacteria. The conversation touches on mechanisms of resistance, global issues, and ethical dilemmas in prescribing carbapenems.

The podcast delves into the history and characteristics of Klebsiella pneumoniae, its pathogenic mechanisms, and the rare K1 syndrome. They explore the resistance mechanisms of Klebsiella bacteria and discuss challenges in treating K-1 Klebsiella infections, including the use of keftazadim and intraocular antibiotics.

In this podcast, the hosts explore the world of gram-negative bacilli, focusing on Enterobacterales and E. coli. They discuss coliforms in microbiology, E. coli antigens, pathogenic mechanisms, and the impact of E. coli infections. The conversation also touches on antibiotic use for E. coli elimination, covering topics like water safety testing, disease differentiation, and diagnostic techniques.

Specialists delve into the world of Beta-lactam antibiotics, discussing aztreonam, temocillin, and pivmecillinam. Tangents lead to C. difficile and carbapenems, offering a unique insight into antibiotic selection and treatment dilemmas for various infections.

In this episode Jame and Callum talk through the two most medically important Gram negative cocci: Neisseria meningitidis and Neisseria gonorrhoeae.Send suggestions to idiotspodcasting@gmail.comSend us a textSupport the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod

Two specialists delve into the world of Cephalosporins, covering their evolution, efficacy in infections, clinical decision-making, resistance mechanisms, and side effects like allergies and Clostridium difficile overgrowth. They discuss the history, spectrum, and challenges of prescribing these antibiotics, providing insights for healthcare professionals.

In this episode Jame and Callum discuss Nocardia and Actinomyces, continuing the journey through Gram positive bacilli.We'll move away from GPBs in the next few episodes before returning to discuss anaerobic GPBs.Send any suggestions to idiotspodcasting@gmail.com, thanks to all those who have submitted feedback and suggestions already!Send us a textSupport the showQuestions, comments, suggestions to idiotspodcasting@gmail.com or on Bluesky @idiots-pod.bsky.socialPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!Feel like giving back? Donations of caffeine gratefully received!https://www.buymeacoffee.com/idiotspod