In this episode of the Smarter Not Harder Podcast, our guest Dr. Michael Levin joins our host Dr. Ted Achacoso to give one-cent solutions to life’s $64,000 questions that include:   Can we unlock the secrets of limb regeneration to revolutionize the future of medicine?  How can we harness the power of cellular communication to control cancer growth?  What are the ethical and practical implications of creating programmable living machines known as xenobots?   Dr. Michael Levin is an acclaimed American developmental and synthetic biologist at Tufts University. As a Vannevar Bush distinguished professor, Dr. Levin has made a remarkable impact in the field of biology, challenging the limits of our understanding and pushing the boundaries of scientific discovery. What we discuss:   [00:00] Dr. Michael Levin's groundbreaking research is shaping the future of biology, medicine, and ethics. [06:25] Bioelectric circuits can be manipulated to grow functioning organs [17:44] Anatomical homeostasis may be the reason for regeneration of limbs in frogs and salamanders [33:02] Xenobots challenge our understanding of natural selection [37:54] Mathematics and geometry have an independent life separate from physical facts of the universe. [53:03] Understanding diverse spaces where intelligence can function. [1:03:23] Planarian bioelectric circuits can be rewritten to alter memory and guide regeneration. [1:18:56] Multicellularity enables cells to work in a different problem space and expand their cognitive light cone. [1:24:06] Recognizing and relating to diverse intelligences through a framework, tools, and ethical considerations. [1:34:31] Understanding and studying agency in unfamiliar embodiments is crucial for the future of living with cognitive systems. [1:39:28] Consider ethics in scientific advancements [1:50:11] Medical informatics is a process of discovering beyond the wall of knowledge. Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg   Find out more from Michael Levin: Website: https://wyss.harvard.edu/team/associate-faculty/michael-levin-ph-d/ Twitter: @drmichaellevin Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org   Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.   

In this episode of the Smarter Not Harder Podcast, our guest Rachel Gerrol joins our host Dr. Scott Sherr to give one-cent solutions to life’s $64,000 questions that include:   What is Nexus, and how has it evolved over the many years since it started? How do the members of Nexus work together to do amazing things all over the world? What are three ways to make your life smarter, not harder?   Rachel Gerrol is widely recognized for her work on millennial philanthropy and community building and has been featured in The New York Times, Financial Times, The Atlantic, Forbes, Vanity Fair, and more. She helped organize the “White House Conference on Next Gen Philanthropy & Impact Investing” for the Obama administration and worked closely with Vice President Biden to develop the “It's On Us” campaign to address sexual assault on campus, which she continues to be an advisor for today. Rachel has received multiple awards and was named in the “Top 99 Foreign Policy Leaders Under 33” by the Diplomatic Courier.    What we discuss:   00:02:34: Rachel’s background in philanthropy  00:05:15: How Rachel became a Philanthropist  00:12:19: What is Nexus?  00:16:57: The challenges of bringing many different people together  00:20:31: The social impact of Nexus 00:27:12: How Nexus supports members all over the world 00:34:41: How to maintain networks and connections 00:39:11: Where is Nexus going in the next 3 to 5 years? 00:43:10: Three ways to help make your life smarter, not harder  Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg   Find out more from Rachel Gerrol: Website: https://nexusglobal.org/ LinkedIn: https://www.linkedin.com/in/rachelgerrol/ Instagram: @rachelgerrol Twitter: @rachelgerrol Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org   Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder Podcast, our guest Dr. Thierry Hertogue joins our host Dr. Ted Achacoso to give 1 cent solutions to the following $64,000 questions: Are hormones perhaps the best psychedelics? How can we use the hormones produced in the seven neuroendocrine axis to anti-age? Can doctors and health care practitioners be taught to include spirituality in practice?  Dr. Thierry Hertoghe pioneered anti-aging medicine using hormones to balance the system into health. He discusses hormone balancing in the podcast. [00:00] Dr. Thierry Hertoghe is an anti-aging expert who uses hormones to balance the body for health [00:40] Why Testosterone and DHEA are essential for overall health [08:31] Growth hormone can improve health, increase freshness, and reduce anxiety in people above 35-40 years [16:03] Peptides are not as effective as growth hormone for stimulating growth due to their effects on only one receptor. [23:36] Thyroid hormone balancing improves bowel movements and intelligence [30:53] Control blood sugar levels with insulin, alpha lipoic acid, and chromium [38:31] Cortisol deficiency leads to severe health problems [53:01] Hormone treatment has good effects if given from pre-menopause to women up to age 60-65 [1:00:01] Balancing estrogen and progesterone is crucial to avoid negative symptoms and improving quality of life. [1:07:22] Spirituality and hormone balancing are essential for overall health. [1:22:13] Incorporating spirituality into medicine will lead to better healing. Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg   Find out more from Dr. Thierry Hertoghe: Website: https://www.hertoghe.eu/en/ Facebook: https://www.facebook.com/DrHertoghe/ Instagram: @dr.hertoghe LinkedIn: https://www.linkedin.com/in/thierry-hertoghe-md-839386b7/ Youtube: https://www.youtube.com/user/HertogheMedschool     Get 10% Off Your Purchase of Metabolomics Module by using PODCAST10 at https://www.homehope.org   Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder Podcast, our guest Dr. Andrew Gallimore joins our host Dr. Ted Achachoso to give 1 cent solutions to the following $64,000 questions:   Does dimethyltryptamine make the brain construct a different reality or does it make the brain perceive a different reality based on the information that it was receiving?  How do molecules such as LSD, DMT, psilocybin, and mescaline switch one’s reality from one channel to another Why is the fly agaric psychedelic?     Dr. Andrew Gallimore is a British neurobiologist, chemist, pharmacologist and writer based in Tokyo, Japan. He has been interested in the relationship between psychedelic drugs, the brain, consciousness, and the structure of reality. He has written a couple of books that he illustrated and self-published. His works are Alien Information Theory: Psychedelic Drug Technologies, and the Cosmic Game (2019), and Reality Switch Technologies: Psychedelics as Tools for the Discovery and Exploration of New Worlds (2022).     What we discuss:   [00:00] Dr. Andrew Gallimore discusses his self-published book on psychedelic drug technologies and the structure of reality [09:12] DMT and Conway's Game of Life illustrate the emergence of complexity from simple rules [25:29] DMT experience reveals highly intelligent, hyper-dimensional space beyond our reality [34:06] DMT allows the brain to construct an alternate reality without affecting critical parts. [49:36] Salvanorin inhibits the claustrum, which releases the cortex and creates novel emergent patterns of activity. [57:19] Salvia tears apart the fabric of reality while classic psychedelics allow the brain to reach new states [1:12:43] Different drugs affect perception and reality in different ways. [1:20:42] Inhibitory interneurons control excitation inhibition balance [1:36:11] Positive allosteric modulators can enhance receptor activity without the presence of an endogenous agonist. [00:15] Muscimol and its Psychedelic Properties   Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg   Find out more about Dr. Andrew Gallimore: Website: http://alieninsect.net/ Twitter: @alieninsect Instagram: @alieninsect YouTube: youtube.com/c/alieninsect  Books: Alien Information Theory: Psychedelic Drug Technologies and the Cosmic Game Reality Switch Technologies: Psychedelics as Tools for the Discovery and Exploration of New Worlds     Get 10% Off Your Purchase of Metabolomics Module by using PODCAST10 at https://www.homehope.org   Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder Podcast, our guest Dr. Nasha Winters joins our host Dr. Scott Sherr to give one-cent solutions to life's $64,000 questions within the cancer realm. Dr. Nasha dives into integrative cancer care and opening a metabolic oncology hospital.   Dr. Nasha Winters is a global healthcare authority and a best-selling author in integrative cancer care and research. She has educated hundreds of professionals in the clinical use of mistletoe, and created robust educational programs for both healthcare institutions and the public on incorporating vetted integrative therapies and cancer care to enhance outcomes. Dr. Winters is currently focused on opening a comprehensive metabolic oncology hospital and research institute in the United States.     What we discussed: [00:00] High insulin levels desensitize cancer cells to radiation [07:20] 10 major drivers to evaluate for each individual's mitochondrial bucket [19:33] A data-driven, individualized approach is key to successful patient outcomes. [25:52] Comprehensive patient history is crucial to evaluate hormone health. [38:23] Gut health plays a significant role in the immune system and cancer therapies [44:46] Individualized treatment is the future of Integrative Oncology. [57:02] Oxidative therapies  [1:03:28] Cancer is a manageable disease process, and standard oncology needs to adapt. [1:15:18] Movement towards caring for emotional and mental well-being   Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg   Find out more about Dr. Nasha Winters: Website: https://www.drnasha.com/ Books: https://www.drnasha.com/matcbook/ Facebook: https://www.facebook.com/drnashainc/ LinkedIn: https://www.linkedin.com/in/nasha-winters-796374b6/ Twitter: https://twitter.com/drnashawinters Instagram: @drnashawinters YouTube: https://www.youtube.com/channel/UCn932xLBUY91v9OHE0YuR6A     Get 10% Off Your Purchase of Metabolomics Module by using PODCAST10 at https://www.homehope.org   Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder podcast, host Dr. Ted Achacoso is joined by Dr. Anna Lembke who educates us on the opioid epidemic and answered the question: how can a person get addicted to pain?   Doctor Anna Lembke is a professor and the medical director of Addiction Medicine at Stanford University School of Medicine, and a New York Times Best Selling author. She received her undergraduate degree in humanities from Yale University and her medical degree from Stanford University.    Dr. Lembke is a diplomat for both the American Board of Psychiatry and Neurology, and the American Board of Addiction Medicine. She is also a specialist in the opioid epidemic of the United States. She appeared in the 2020 subcommittee The Social Dilemma.  Her works include “How Doctors Were Duped, Patients Got Hooked, and Why It’s So Hard to Stop,” and the New York Times bestseller “Dopamine Nation: Finding Balance in the Age of Indulgence” which was released in August 2021.      What we discuss: 00:00:40 - About Dr. Anna Lembke 00:01:45 - Uncovering co-occurring addictions alongside subsctance abbuse  00:03:46 -  Uncovering substance addictions with behavioral-addicted patients 00:04:54 - Is it true that people have addictive personalities? 00:08:02 -  Decreasing the amount of the addictive substance over time vs. total abstinence immediately 00:13:16 - Statistics on substance addiction  00:18:14 - How dopamine plays into addiction  00:22:23 - The journey to abuse  00:30:08 - How does one get addicted to pain?  00:39:28 - What happens to dopamine once abstinent  00:42:55 - How does opiate induced hyperalgesia happen? 00:46:25 - How does mindfulness help with addiction?  00:52:02 - Is romantic love an addiction? 00:53:48 - Should hard and sudden heartbreak be treated with drugs from sudden dopamine drops? 00:57:42 - Can psychedelics lead to addiction? Can it help in mitigating addiction?  01:00:29 - Smarter not harder advice to parents on how their children can navigate the dopamine nation     Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg   Find out more about Dr. Anna Lembke: Website: https://www.annalembke.com/ Dopamine Nation: https://www.annalembke.com/dopamine-nation Publications: https://www.annalembke.com/selected-publications     Get 10% Off Your Purchase of Metabolomics Module by using PODCAST10 at https://www.homehope.org   Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of Smarter Not Harder, host Dr. Scott Sherr is joined by guest Dr. Dave Rabin. Dr. Rabin dives into psychedelics, neuroplasticity, ketamine, and his technology Apollo. He also discusses the parasympathetic and sympathetic nervous system and the balance in creating a safe space for patients when they are going through psychedelic assisted psychotherapy or mental health treatment. Dr. Rabin ends the episode by sharing about his nonprofit organization, his most recent W.H.O. adventures, and his talks on psychedelics and ketamine in underdeveloped nations.   Dr. Dave Rabin is a clinical neuroscientist and an M.D. Board certified psychiatrist. He is an M.D. and Ph.D. at the Albany Medical College and specialized in psychiatry with a distinction of research at the Western Psychiatric Institute and clinical at the University of Pittsburgh Medical Center. He is also a health tech entrepreneur. He invented the Apollo and his company, Apollo Neuroscience is creating wearable technology, using touch and simulating touch. Additionally, he co-founded the Board of Medicine and serves as its executive director. Dr. Dave is conducting research on epigenetic regulation of trauma responses and recovery to elucidate the mechanism of psychedelic assisted psychotherapy in the neurobiology of belief.      What we discuss:   00:00:40 - About Dr. Dave Rabin 00:05:18 - About psychedelics and neuroplasticity 00:08:36 - Psychedelics and ketamine 00:12:12 - The mechanisms of ketamine  00:20:21 - Opioid receptors with ketamine being dose dependent  00:27:46 - Balancing the sympathetic and parasympathetic nervous systems  00:34:30 - Dr. Rabin approach to training other doctors and practitioners  00:46:47 - How Dr. Rabin treats his patients in a clinical setting 00:55:30 - The Apollo  01:01:16 - What to prioritize in-session and post-session (ketamine) 01:06:14 - The default mode network  01:11:01 - How to handle bad psychedelic experiences     Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg   Find out more about Dr. Dave Rabin: Website: http://apollo.clinic/ | https://apolloneuro.com/ | https://www.boardofmedicine.org/ Podcast: https://www.thepsychedelicreport.com/ Twitter: https://twitter.com/drdavidrabin Instagram: https://www.instagram.com/drdavidrabin/ LinkedIn: https://www.linkedin.com/in/drdavemdphd/   Get 10% Off Your Purchase of Metabolomics Module by using PODCAST10 at https://www.homehope.org   Get 10% Off your Trosciptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder podcast, we are joined by the father of Biohacking, Dave Asprey. He educates us on the laziness principle and how to utilize it to our advantage, exposomics and epigenetics, and if spirituality can be hacked.   Dave Asprey is a four-time New York Times bestselling science author, the creator of the Bulletproof Coffee, the founder of the Bulletproof Company, and is also known as “the Father of Biohacking”.   He attended  University of California, Santa Barbara and majored in computer science and later earned his undergraduate degree in computer information systems from California State University, Stanislaus. He then earned his MBA from Wharton. He is also the host of the Webby award-winning podcast “The Human Upgrade with Dave Asprey” and has been featured in different outlets such as Men’s Health, Wired, the Joe Rogan Experience, CNN, and more.   What we discuss:   00:00:31 - About Dave Asprey 00:05:15 - About Dave’s book, “Smarter Not Harder” 00:05:55 - How can laziness make us strong? 00:10:57 - Why the body wants to conserve energy rather than using it 00:12:55 - How does one cheat the spike? 00:19:47 - How does it become an inside job? 00:25:35 - What is exposome and what’s glyphosate got to do with it? 00:27:22 - What are lectins and why should we avoid them? 00:34:35 - More about Vitamin D  00:42:42 - Why mitochondria is focused on in his book?  00:45:21 - What are omega six fatty acids and why are they a double edged sword? 00:51:16 - What is PQQ and what does it do? 00:52:25 - Does PQQ affects the ratio of cardiolipins in the mitochondria?  00:53:44 - How does a pulsed EMF affect your energy level and metabolism? 00:56:32 - What is HUSO? 01:00:32 - How do we hack the epigenome and what does the test that measures ones’ epigenetic age do? 01:04:54 - Dave’s opinion on 3D printed meat 01:05:01 - How did coming to terms with emotions help Dave in his divorce? 01:10:12 - Why is equanimity the highest spiritual target?  01:12:26 - Dave’s top 3 Smarter Not Harder hacks to live a happy life 01:14:45 - Dave’s take on psychedelics     Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg   Find out more about Dave Asprey: Website: https://daveasprey.com/ Podcast: https://daveasprey.com/category/podcasts/ Smarter Not Harder by Dave Asprey: https://www.amazon.com/Smarter-Not-Harder-Biohackers-Getting-ebook/dp/B0B399L6KP?ref_=ast_author_dp Other Books: https://daveasprey.com/books/ Twitter: @bulletproofexec Instagram: @dave.asprey LinkedIn: https://www.linkedin.com/in/asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/   Get 10% Off Your Purchase of Metabolomics Module by using PODCAST10 at https://www.homehope.org   Get 10% Off your Trosciptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

Why should doctors and health care practitioners learn about artificial intelligence? This is one of the main topics we dive into in this episode of the Smarter Not Harder podcast with guest, Karl Friston.  Karl John Friston FRS FMedSci FRSB is one of the greatest scientists in history whose work has been cited over 245,000 times. He is a British neuroscientist and theoretician at University College London. He is an authority on brain imaging and theoretical neuroscience, especially the use of physics-inspired statistical methods to model neuroimaging data and other random dynamical systems. Karl gives us one cent solutions for the following $64,000 dollar questions:  1. What does "I am therefore I think" mean in the context of the free energy principle? And, what do psychedelics have to do with it? 2. How does one go about inventing in tools to investigate this connection hypothesis of schizophrenia? 3. Why should doctors and health care practitioners learn about artificial intelligence?  If you want to the answers to these questions, hold on tight, we're about to go on an extremely deep dive into these topics! What we discuss:  0:00:43- About Dr. Karl Friston 00:7:22- The disconnection hypothesis of schizophrenia 00:12:07- The challenges of developing tools to investigate the connection hypothesis of schizophrenia 00:24:14 The difficulties of presenting ideas that are ahead of time  00:32:01 How Dr. Karl Friston got involved in the COVID situation 00:45:16 The free energy principle and coacervate droplets 00:59:13 Is biological life necessary for consciousness or is self evidencing enough?  01:09:50 The different theories for explaining the nature of things 01:18:18 The uncertainty of beliefs  01:26:03 What is the REBUS model? 01:33:16 How psychedelics can induce entropy in a controlled way  01:46:37 The definition of Artificial Intelligence  01:51:59 What is the embodied cognition? 01:58:06 Is curiosity necessary for the expression of the free energy principle?   02:14:05 Learning as humans in evolution  02:27:35 The future of machine learning models  02:33:00 What imaging tools need to be developed for the future 02:41:31 What’s next for pharmacology 02:51:59 How we should proceed with psychedelic research Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast / https://homehope.org Instagram: @troscriptions | @homehopeorg   Get 10% Off Your Purchase of Metabolomics Module by using PODCAST10 athttps://www.homehope.org   Get 10% Off your Trosciptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of Smarter Not Harder podcast, we are joined by Dr. Nicole Bijlsma.  She chats with host Jodi Duval about all things environmental medicine, including why these exposures are so crucial to health, how the environment effects health, what we can do to mitigate these effects, what an environmental exposure history questionnaire is, how to use it in practice, and so much more.   Dr. Nicole Bijlsma is a building biologist, bestselling author, Ph.D. candidate and the CEO of the Australian College of Environmental Studies. She has 30 years of experience lecturing at academic institutions and was formerly a naturopath and acupuncturist. She has written extensively for the Body and Soul newspaper in the Herald Sun, has articles published in peer-reviewed journals, and is frequently consulted by the media to discuss mold, electromagnetic fields, and toxic chemicals. She also gives talks about environmental health issues in Australia and abroad.   What we discuss:    00:00:22 - How Dr. Nicole entered into the environmental medicine space 00:09:34 - Environmental medicine’s effect on people’s emotions  00:11:48 - Environmental exposure to EMFs  00: 21:16 - Environmental exposure to molds 00:23:08 - Are we ever going to adapt to these environmental changes? 00:37:48 - What is the difference between living near the forest and near the ocean?  00:43:20 - Environmental exposure to toxic metals 00:47:09 - What is an environmental exposure history questionnaire and how is it used?  00:57:15 - What’s next for Dr. Nicole Bijlsma?   Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast / https://homehope.org Instagram: @troscriptions | @homehopeorg   Find out more about Dr. Nicole Bijlsma: Website: https://www.buildingbiology.com.au/ Facebook: https://www.facebook.com/nicolebijlsma1 Instagram: https://www.instagram.com/colbijlsma/   Get 10% Off Your Purchase of Metabolomics Module by using PODCAST10 at https://www.homehope.org   Get 10% Off your Trosciptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.