In this episode of the Smarter Not Harder Podcast, our guest Dr. Ted Achacoso joins our host Boomer Anderson to give one-cent solutions to life’s $64,000 questions that include: What are some things that are commonly misunderstood about the mitochondria? How are common drugs in the anti-aging world poisoning the mitochondrial complexes?  Why is the holobiont perspective particularly important for the mitochondria?   Dr. Ted is the founding pioneer of Health Optimization Medicine and Practice, a 501(c)3 nonprofit organization dedicated to helping doctors and practitioners learn how to optimize for health rather than treat disease. He is also the founder of Smarter Not Harder Inc, makers of Troscriptions. He went to med school at the age of 18, and is trained in interventional neuroradiology, toxicology and pharmacology. He is also trained in anti-aging medicine, nutritional medicine, and is an expert in hormone balancing. What we discuss: [00:08:22] Intermittent fasting and ketogenic diets affect autophagy and mitochondrial biogenesis [00:20:17] The body uses signaling molecules to sense the body's energy needs [00:24:22] Mitochondria decrease in population and acquire mutations as we age [00:31:18] Mitochondrial haplotypes can vary based on geographic location and climate [00:39:44] Keeping cells in network control prevents proliferation [00:42:07] For any supplement to work, it has to pass the double membranes of the mitochondria [00:50:16] Testing is necessary to recommend lifestyle modifications objectively [01:00:04] Supplementation can correct imbalances in the mitochondria Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg   Find out more from Dr. Ted Achacoso: https://homehope.org Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org   Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.   

In this episode of the Smarter Not Harder Podcast, our guest Dr. Janet Schloss joins our host Jodi Duval to give one-cent solutions to life’s $64,000 questions that include:   What are some of the intricacies of the endocannabinoid system, and how can it impact our health?  How can medical cannabis be used in the treatment of chronic disease and conditions? What are the challenges of designing research studies around medical cannabis?   Dr. Janet Schloss is the Clinical Research Fellow at the National Centre for Naturopathic Medicine at Southern Cross University. Janet is an accomplished researcher with extensive experience in coordinating clinical trials. In addition to her academic career, Janet is a practicing clinical nutritionist and naturopath with over 20 years of experience. Following the completion of her doctorate in 2015, Janet has focused her research on supporting people who have cancer through studying the use of complementary medicine to assist side effects of cancer treatments. Janet has completed a number of groundbreaking studies and has over 60 publications, and now focuses a lot of her research on medical cannabis.  What we discuss: [00:00] Medical cannabis has gained recognition as a powerful tool in healthcare. [07:03] Researching medicinal cannabis for GBM [13:22] Medicinal cannabis has potential but is not right for everyone [19:15] Understanding the different cannabinoids and their effects [24:59] Medical cannabis has promising applications in chronic diseases, stress, anxiety, and inflammation. [30:42] Exciting opportunities in cannabis research for neurological conditions [36:28] Cannabis products can aid in chemotherapy and adjunct treatment [41:54] Educating patients on medicinal cannabis is crucial [47:24] Titration of cannabis is individualized and requires slow and steady dosing. [52:45] Timing and proper dosage are crucial for effective cannabis treatment [58:36] Antioxidants are not what we think they are Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg   Find out more from Dr. Janet Schloss: https://www.janetschloss.com/ LinkedIn: https://www.linkedin.com/in/janet-schloss-9a30a48/?originalSubdomain=au Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org   Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.  

In this episode of the Smarter Not Harder Podcast, our guest Alex Rosenberg joins our host Boomer Anderson to give one-cent solutions to life’s $64,000 questions that include:   What are the definitions of scientism and naturalism? Is there such a thing as free will, and if so, what implications does it have on the search for purpose in life? What is nice nihilism?   Alex Rosenberg is an American philosopher and novelist. He is the R. Taylor Cole Professor of Philosophy at Duke University, and is well known for contributions in the philosophy of biology, as well as the philosophy of economics. He has also written several books, including "The Atheist's Guide to Reality: Enjoying Life without Illusions" and "Philosophy of Science: A Contemporary Introduction." What we discuss: [00:00] Fundamental laws of physics are time symmetrical [06:53] Naturalism requires letting go of everyday reality and embracing science. [13:43] The second law of thermodynamics governs the emergence of organized adaptive systems. [20:31] The content of conscious thought is an illusion. [27:25] Self-help industry is exploiting people's credulity. [34:10] Our continual dissatisfaction is a result of natural selection. [40:58] Do we have free will? [47:34] Nice nihilism is the doctrine that most of us behave in ways that are satisfying to the emotional responses of others. [54:10] Living in the moment may not lead to happiness [1:00:53] Seek professional advice driven by science for living smarter. Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg   Find out more from Alex Rosenberg: https://alexrosenbergbooks.com/ https://scholars.duke.edu/person/alexrose   Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org   Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.  

Dr. Mark Gordon, an expert in traumatic brain injury, PTSD, and hormonal optimization, discusses the link between stress, cortisol, and brain injury. He also highlights the importance of vitamin D for the immune system and testosterone production. Balancing all hormones is crucial for overall health. Topics include: PTSD and TBI connection, significance of hormone optimization, reducing brain inflammation, addressing inflammation in clinical practice, role of testosterone in brain function, and optimizing growth hormone production.

In this episode of the Smarter Not Harder Podcast, our guest Dr. Brad Leech joins our host Jodi Duval to give one-cent solutions to life’s $64,000 questions that include:   What are the benefits of a healthy microbiome and how do we measure this? What does the gut microbiome do for us, and how does the microbiome interact with systemic health? What are some new advancements surrounding the microbiome in recent years, and what does this mean or change for us clinically? Dr. Brad Leech is a PhD-qualified Clinical Nutritionist specializing in chronic autoimmune conditions and complex gastrointestinal disorders. He provides complete and personalized care to his patients using functional nutrition, integrative medicine and holistic wellness. After entering the profession in 2008, Brad has taught and developed subjects at leading universities and conducted research on intestinal permeability, autoimmune disease management and food-based probiotics. Brad is the Lead Clinical Educator and co-creator of Co-Biome, where his expertise in gastrointestinal healthcare enables him to translate the latest science on the gut microbiome into practical clinical applications. In addition to his research, and working with patients, Brad offers practitioner support through his mentoring program Brad’s Brainiacs. What we discuss: [00:00] A healthy microbiome is essential for optimal health and can reduce the risk of chronic diseases [07:40] Diversity in diet is key for a healthy microbiome [14:16] The gut microbiome produces metabolites that impact systemic health [21:10] Microbiome diversity and production of beneficial compounds are linked to various health conditions [27:31] Advanced sequencing methods allow for a comprehensive understanding of the microbiome. [34:21] Metagenomics can identify 28,000 bacterial species and their functions [40:55] Personalized medicine is the new approach to treating dysbiosis [46:54] Reduce LPS-producing bacteria through prebiotic fiber, bovine colostrum, and reducing saturated fats [53:16] Increase butyrate production with resistant starch and diverse fiber [59:41] Recommended daily fiber intake is around 30 grams for females and 38 grams for males Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg   Find out more from Dr. Brad Leech: Website: https://drbradleech.com/ Instagram: @drbradleech Twitter: @drbradleech LinkedIn: https://www.linkedin.com/in/drbradleech/ Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org   Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.  

In this episode of the Smarter Not Harder Podcast, our guest Scott Carney joins our host Boomer Anderson to give one-cent solutions to life’s $64,000 questions that include:   How does something go from an idea, to a story, to a book?  How can one go wrong in the pursuit of what is otherwise known as a noble path? What is the relationship between the dark side of spirituality and the pursuit of enlightenment?   Scott Carney is a New York Times bestselling author, anthropologist and investigative journalist. His works include What Doesn’t Kill Us, The Vortex, The Wedge, The Red Market and The Enlightenment Trap. Carney was a contributing editor at Wired for five years and his writing also appears in Mother Jones, Men’s Journal, Playboy, Foreign Policy, Discover, Outside and Fast Company. His work has been the subject of a variety of radio and television programs, including on NPR and National Geographic TV.  What we discuss: [00:00] The rule of social media is the same as the rule of improv [06:38] The moment that instigated the majority of what Scott has written  [17:43] Spirituality can be a tool to become a good person, but it can also lead to spiritual bypassing [23:32] Exploring the dangers of spiritual journeys and gurus [39:58] The authenticity of Eastern spiritual traditions is often overestimated [50:57] Beware of warning signs in spiritual and health communities that may indicate cult-like behavior [01:13] The problem with health gurus and their untested ideas [1:06:49] The potential dangers of the Wim Hof method [1:12:02] The dangers of blindly following gurus and influencers Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg   Find out more from Scott Carney: https://www.scottcarney.com/ Instagram: @sgcarney Twitter: @sgcarney Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org   Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.   

In this episode of the Smarter Not Harder Podcast, our guest Dr. Ted Achacoso joins our host Boomer Anderson to give one-cent solutions to life’s $64,000 questions that include: What is evolutionary medicine, and what is its role in the Health Optimization Medicine and Practice framework? How does Universal Darwinism play a role in health optimization medicine? How are master regulatory genes and the cell danger response related to each other?   Dr. Ted is the founding pioneer of Health Optimization Medicine and Practice, a 501(c)3 nonprofit organization dedicated to helping doctors and practitioners learn how to optimize for health rather than treat disease. He is also the founder of Smarter Not Harder Inc, makers of Troscriptions. He went to med school at the age of 18, and is trained in interventional neuroradiology, toxicology and pharmacology. He is also trained in anti-aging medicine, nutritional medicine, and is an expert in hormone balancing.    What we discuss: [00:00] Evolutionary medicine's role in health optimization medicine. [06:59] Medicine has gone through magical, religious, empirical, and rational phases and is now moving towards an evolutionary phase. [13:27] Health Optimization Medicine focuses on the body's mechanisms for healing, rather than just getting rid of diseases. [19:45] Universal Darwinism applies from molecules to galaxies. [25:42] Looking at cells and metabolites to understand the body's ecosystem. [31:30] Metabolic neotenization is key for optimal health. [37:28] Master regulatory genes and the cell danger response are related to each other. [43:28] The body has summer and winter metabolisms that alternate within a day, and understanding them is key. [49:34] Evolutionary medicine provides a first principles approach to health optimization. Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg   Find out more from Dr. Ted Achacoso: https://homehope.org   Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org   Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.  

In this episode of the Smarter Not Harder Podcast, our guest Brian Mackenzie joins our host Dr. Scott Sherr to give one-cent solutions to life’s $64,000 questions that include:   Why is CO2 so important in respiratory physiology? How does building up CO2 tolerance affect not only your parasympathetic and sympathetic nervous systems, but your aerobic and anaerobic metabolism as well? What is the importance of nasal breathing? Brian is the founder and CEO of SHIFT, a comprehensive and adaptive training program that focuses on breath control as a primary tool for improving performance. He is also the president and co-founder of the Health and Human Performance Foundation, a nonprofit organization dedicated to the research on how breath and innate tools can optimize and help health and human performance. He's an innovator in human performance on stress adaptation, and a pioneer in the development and application of custom protocols to optimize human health and performance. His work harnesses and integrates respiratory movement, strength conditioning and endurance based training approaches to elicit unprecedented positive results. His protocols have been used to accelerate and raise both mental and physical performance in world class Olympic and professional athletes, top executives and elite military operators, as well as to improve the health for people suffering from various chronic and pathological issues.    What we discuss: [00:00] Understanding stress response and respiratory physiology [06:15] Positive prison population leads to positive staff population [17:59] Our attention span is decreasing due to technology and distractions. [23:29] Stress response is a human trait, hardwired in us, but we need to actively work on keeping it in check. [34:53] Hyperventilation can cause stress on the heart and disrupt the nervous system. [40:16] CO2 tolerance affects anxiety levels. [51:36] Breathing control can improve athletic performance. [57:11] Mouth breathing impacts aerobic capacity. [1:07:33] Breathing through the nose and chewing hard food can improve CO2 tolerance and prevent sleep apnea. [1:12:25] Manage stress and develop breath control before practicing breath hold techniques. [1:23:38] Manage stress by identifying stressors, avoiding reactive responses, and becoming aware of stressors in life for personal growth. [1:29:23] SHIFT is a membership site that offers programs to make everything more accessible to people.   Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg   Find out more from Brian Mackenzie: https://www.hhp-foundation.org/ Instagram: @_brianmackenzie   Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org   Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.  

In this episode of the Smarter Not Harder Podcast, our guest Dr. Lucia Aronica joins our host Dr. Scott Sherr to give one-cent solutions to life’s $64,000 questions that include:   What is the definition of epigenetics, and what are common epigenetic modifications? What were the results from the DIETFITS study? What are the various types of epigenetic clocks, and what are the best ways to use them?   Dr. Lucia Aronica is a lecturer at Stanford University and instructor of the Stanford Genomics Certificate. Her research and teaching focused on nutrigenomics: the science of how nutrition, genetics and epigenetics interact with each other to impact our health and longevity. She has 20 years of research experience from Stanford University, the University of Oxford, the University of Vienna, the University of Naples Federico II, and the University of Southern California. She's published research papers in top ranked, peer reviewed journals such as JAMA, Cell, and Genes & Development.   What we discuss: [00:00] Health optimization medicine focuses on optimizing health through epigenetic biomarkers and metabolomics. [05:36] Epigenetic modifications involve DNA methylation and histone modifications that regulate gene expression. [14:30] Epigenetics affects our health through lifestyle choices and can be viewed as a secret agent of optimization medicine. [21:13] Lifestyle can override the effect of common genetic variants. [27:39] The DIETFITS study analyzed biomarkers to determine which categories of people would benefit from low-carb or low-fat diets [41:40] Reduce carb intake and increase whole food intake for better metabolic and brain health. [48:19] Omega-3s are conditionally essential nutrients which are difficult to synthesize from plant-based sources, making it better to get them from animal-based sources. [54:29] Epigenetic clocks can estimate biological age and capture functional changes in the body but there’s a catch [1:00:57] Be cautious about using epigenetic clocks for clinical utility [1:07:26] Sign up for Dr. Lucia Aronica's webinar on epigenetics and longevity   Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg   Find out more from Dr. Lucia Aronica: https://draronica.com/ LinkedIn: https://www.linkedin.com/in/luciaaronica/ Instagram: @drluciaaronica   Dr. Aronica’s free webinars and new certificate course in epigenetics: https://draronica.podia.com Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org   Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram. 

In this episode of the Smarter Not Harder Podcast, our guest Dr. Joscha Bach joins our host Dr. Ted Achacoso to give one-cent solutions to life’s $64,000 questions that include:  Will physicians and other healthcare providers be replaced by AI technologies? Can AI help solve the most frightening aspects of US healthcare, or are we beyond solutions? What is the future of conscious machines?   Dr. Joscha Bach is a renowned AI researcher and cognitive scientist, known for his work in understanding the complex architecture of the human mind. Dr. Bach holds a Ph.D. in Cognitive Science from the University of Osnabrück in Germany, and has worked as a research scientist at the MIT Media Lab, as an affiliate at the Harvard Program for Evolutionary Dynamics, and as Principal AI Engineer at Intel Labs Cognitive Computing group. He has published extensively on cognitive architectures, mental representation, emotion, social modeling, and multi-agent systems. This may be the very first recorded conversation with Dr. Bach that is centered on the role of AI in medicine and health care. What we discuss: [00:00] Empathy is important, but it's also important to develop distance and reflection about yourself. [06:38] AI-generated medical suggestions can be useful but should not be the sole source of advice. [18:14] Alternative regulatory systems can compete with existing ones to introduce pressure for change. [23:51] Regulation can stifle innovation and harm new industries. [35:15] Automated decision tools can create a degree of fairness that you might otherwise not have. [40:52] Understanding death as a part of life and dying with dignity. [52:19] Building an empathetic AI is possible, but it requires a deep understanding of moral and ethical contexts. [57:33] AI's role in advancing diagnostics and therapeutics. [1:09:10] Simulation can aid in identifying factors but real-world context is important. [1:14:48] The only difference between a drug and a poison is the dose. [1:25:39] Exploring the relationship between biological life and consciousness. [1:31:17] Developing a self requires coupling to the world and discovering oneself in it. [1:42:10] Health optimization medicine regards the body as an ecosystem of cooperating and competing cells in the network. [1:47:49] AI can be helpful in healthcare, but professionals need to understand the formal tools to make progress. [1:58:45] Adaptive AI for industrial robots [2:04:30] Building meaningful relationships is the most important thing in life.   Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg   Find out more from Joscha Bach: Website: http://bach.ai/ Twitter: @plinz Get 10% Off Your Purchase of the Metabolomics Module by using PODCAST10 at https://www.homehope.org   Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com   Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.