Thomas Seyfried, a biology and genetics professor at Boston College, dives into groundbreaking cancer research. He argues that cancer should be viewed as a metabolic disease influenced by diet rather than just genetics. Seyfried reveals the alarming global rise in cancer cases and explores the significant role of blood sugar and modern eating habits in cancer growth. He emphasizes the benefits of calorie restriction, exercise, and ancestral dietary practices in prevention and management. This conversation challenges conventional views and advocates for a shift toward metabolic therapy.

Professor Thomas Seyfried, a cancer researcher, explains how malfunctioning mitochondria is at the root of cancer. He discusses the impact of diet and lifestyle on cancer, the role of exercise, and the reliance of cancer cells on fermentation for energy. The podcast also explores informed consent, radical remission, effectiveness of ketogenic diets, glucose ketone ratio, controversy surrounding cancer treatment and weight loss, and tackling obesity.

In this episode, Thomas Seyfried, a cancer researcher and professor of biology at Boston College, discusses a controversial view of cancer as a mitochondrial metabolic disease. Many topics related to the causes, treatments, and prevention of cancer are covered in this in-depth conversation. We discuss: How Tom got interested in cancer research [9:00]; Calorie-restricted ketogenic diets, fasting, and epileptic seizures [18:30]; Otto Warburg and the Warburg effect [30:45]; Germline mutations, somatic mutations, and no mutations [42:00]; Mitochondrial substrate level phosphorylation: Warburg’s missing link [51:30]; What is the structural defect in the mitochondria in cancer? [1:02:00]; Peter’s near-death experience with the insulin suppression test while in ketosis [1:06:30]; Insulin potentiation therapy and glutamine inhibition [1:13:15]; The macrophage fusion-hybrid theory of metastasis [1:39:30]; How are cancer cells growth dysregulated without a mutation? [1:47:00]; What is the dream clinical trial to test the hypothesis that we can reduce the death rates of cancer by 50%? [2:03:15]; How can the hypothesis be tested rigorously that structural abnormalities in the mitochondria impair respiration and lead to compensatory fermentation? [2:26:30]; Case studies of GBM survivors [2:32:45]; and More. Learn more at www.PeterAttiaMD.com Connect with Peter on Facebook | Twitter | Instagram.

Thomas Seyfried, PhD is a preeminent cancer expert and professor in the department of biology at Boston College. He received a PhD in 1976 in genetics and neurochemistry from the University of Illinois at Urbana-Champaign, followed by a postdoctoral degree from Yale University in the field of neurochemistry and genetics. Become a Genius Life Premium Member and get ad-free episodes of the show, a monthly Ask Me Anything (AMA), and more! Learn more: http://thegeniuslife.com

Thomas Seyfried, a leading cancer expert with over three decades of research, dismantles the notion of cancer as purely a genetic disease, framing it instead as a metabolic disorder driven by lifestyle. He highlights how glucose and glutamine fuel cancer cells and discusses the potential of metabolic therapies, including the ketogenic diet, for prevention and treatment. Seyfried also critiques traditional treatments, advocating for a focus on mitochondrial health and lifestyle factors to better combat the rising cancer epidemic.