Ep 62 - Carnivore Diet with Prof Thomas Seyfried | #1 Cancer Expert: The WORST Food That Feeds Cancer Cells
Sep 24, 2023
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Listen to Prof Thomas Seyfried, the #1 cancer expert, as he shares insights on the carnivore diet and how cancer is a mitochondrial metabolic disease. Discover the worst foods that feed cancer cells and learn about the potential of metabolic therapy as an alternative treatment. Explore the impact of foods, fasting, and adopting a healthy lifestyle to prevent cancer and other chronic diseases.
Cancer is a mitochondrial metabolic disease; it's not genetic.
Maintaining healthy mitochondria is key in preventing and treating cancer through metabolic therapy.
Nutritional ketosis and targeted drugs, like glutamine inhibitors, have shown promise in managing cancer and improving overall health.
Deep dives
Cancer Prevention and Metabolic Disease
Cancer is not a genetic disease but a metabolic disease. By recognizing that cancer is a mitochondrial metabolic disease of energy metabolism, the death rate can be reduced by more than 50% in five years. Obesity has replaced smoking as one of the top risk factors for cancer. Maintaining healthy mitochondria is key in preventing cancer. Nutritional ketosis, a diet low in carbohydrates and high in healthy fats, keeps the mitochondria in an energy-efficient state, preventing the growth of cancer cells. Metabolic therapy, a combination of a ketogenic diet and targeted drugs, such as glutamine inhibitors, can effectively treat cancer and improve overall health. The current standard of care, radiation and chemotherapy, often have harmful side effects and don't address the root cause of cancer, making metabolic therapy a promising alternative.
The Root Cause of Cancer and Mitochondrial Dysfunction
Cancer is caused by mitochondrial dysfunction, disrupting energy metabolism in cells. The mitochondria, which produce energy for cells, become damaged, leading to dysregulated cell growth. The disruption of oxidative phosphorylation in mitochondria, not gene mutations, is the origin of cancer. Secondary risk factors, such as exposure to carcinogens, viral infections, and even old age, can contribute to mitochondrial dysfunction. Glucose and glutamine are the primary fuel sources for cancer cells, making cancer a disease of energy metabolism. All cancers, regardless of the organ affected, are highly fermentative cells with dysregulated growth. Understanding the root cause of cancer helps in developing effective strategies, like metabolic therapy, to target cancer cells.
Treating Cancer with Metabolic Therapy
Metabolic therapy focuses on maintaining healthy mitochondria to prevent and treat cancer. Nutritional ketosis, achieved through a ketogenic diet, enhances mitochondrial energy efficiency and reduces reactive oxygen species. Metabolic therapy also employs targeted drugs, such as glutamine inhibitors, to block fuel sources for cancer cells. By combining nutritional ketosis and targeted drugs, tumors can be deprived of energy and killed naturally without causing toxicity. Metabolic therapy has shown promise, particularly in managing aggressive cancers like glioblastoma. It provides an alternative to standard treatments like radiation and chemotherapy, which often have limited efficacy and harmful side effects. Education and awareness are crucial in bringing about changes in cancer treatment and empowering patients to explore metabolic therapy.
Importance of Nutritional Ketosis and Transitioning to Water Fasting
The podcast discusses the importance of nutritional ketosis for cancer patients and outlines a recommended dietary approach. It is suggested that going on a zero-carb diet for 10 to 14 days can help achieve nutritional ketosis, and transitioning from this state to water fasting is easier for the body. Maintaining low GKI values (glucose ketone index) is emphasized, as a GKI of 2.0 or below indicates being in ketosis. The discussion also touches on the continuous state of ketosis for individuals like Dom Diagostino, highlighting the need to personalize dietary choices and the option for occasional indulgences.
Understanding Glutamine Fermentation and Targeting Glucose and Glutamine
The podcast explores the role of glutamine fermentation in cancer cells and its implications for cancer treatment. Glutamine is found to be fermented in the mitochondria of cancer cells, providing them with energy. Targeting both glucose and glutamine is necessary to inhibit cancer cell growth effectively. The ketogenic diet, along with drugs that target glutamine, is highlighted as a potential therapeutic approach. The discussion emphasizes the need for further research to fully understand and manage cancer, while acknowledging that metabolic therapy shows promise in managing cancer and improving overall health.
