Scientist Matt Clancy discusses the risks and benefits of accelerating scientific progress, highlighting the potential consequences of genetic engineering advancements. The conversation explores the ethical implications of discount rates, the economic impact of science on income growth, and the costs associated with global biological catastrophic risks. Clancy advocates for strategic investments in science to maximize social impact and address extinction risks in a balanced manner.

Matt Clancy, an innovation economist and author, dives into the intriguing decline of productivity growth since the 1960s despite rising R&D investments. He explores whether society has become too risk-averse or if we've exhausted easier scientific advancements. Clancy discusses the limitations of traditional research funding and the need for experimental approaches to rejuvenate innovation. He also highlights the optimistic potential of AI in fostering collaboration and enhancing scientific productivity, proposing a more adventurous funding landscape.

In this discussion, Tom Kalil, CEO of Renaissance Philanthropy and former White House advisor, alongside economist Matt Clancy, dive into the importance of innovation prizes and the art of ‘influence without authority’. They challenge the ambition level of ultra-wealthy philanthropy and ponder whether policy entrepreneurship can be formally taught. Kalil shares insights from his experience working with Gordon Moore, while Clancy highlights the pivotal role of young professionals in revitalizing U.S. state capacity and bridging research with actionable policy.

Join economist Matt Clancy, Stripe co-founder Patrick Collison, and OpenPhil CEO Alexander Berger as they explore whether scientific progress is really slowing down. They discuss the challenges in measuring scientific breakthroughs, revealing a paradox of increasing funding yet declining impact. The conversation dives into how historical evidence, evolving practices, and innovations like AI may influence future advancements. With insights on institutional reforms and diverse funding, they argue for a renewed focus on enhancing scientific productivity.

Dylan Matthews, a journalist known for his insights on economics, joins experts Tyler Cowen, a professor at George Mason University, Matt Clancy, and Jacob Trefethen from Open Philanthropy. They dive into the balancing act between scientific advancement and safety, using historical case studies to illustrate their points. Discussions cover the dual-edged nature of innovation, ethical responsibilities in frontier science, and the risks associated with AI competition. They emphasize the importance of effective risk management to harness the benefits of scientific progress.