JAMA Editor in Chief and a professor of pediatrics discuss how AI can reduce clinician burden and streamline health systems. Topics include AI in the back office of healthcare, types of studies needed in AI and clinical practice, equitable considerations in applying new technologies, and transforming electronic health records with AI.

JAMA Editor in Chief Kirsten Bibbins-Domingo and UCSF's Chief Research Informatics Officer Ida Sim discuss the transformative potential of AI in medicine, exploring generative AI and large language models. They reflect on AI augmentation in medicine and the importance of AI in medical practice. The potential role of AI in clinical practice is also explored, emphasizing the need for collaboration between computer science and medical professionals in AI innovation.

Kirsten Bibbins-Domingo, an esteemed editor in chief of a prominent medical journal, dives into groundbreaking topics. She discusses the implications of aspirin discontinuation during pregnancy to mitigate preterm preeclampsia risks. The genetic link between APOE variants and Alzheimer's disease in African ancestry populations is examined, highlighting critical health disparities. Additionally, there’s an analysis of low wages correlating with increased mortality and an emphasis on innovative insulin pricing in California, alongside a reevaluation of sepsis management and the prevalence of brain malignancies.

Kirsten Bibbins-Domingo, the Editor in Chief of JAMA, dives into groundbreaking trials from the ESC 2024 Congress. She discusses the impact of antihypertensive continuation before surgery and potassium's role post-cardiac surgery. A key highlight is a triple-drug combination pill aimed at tackling resistant hypertension in Africa, showing promise in improving patient outcomes. Lastly, Bibbins-Domingo emphasizes innovative methods to manage hypertension in Nigeria, pointing to a significant leap in treatment efficacy. This conversation is a treasure trove for cardiovascular health enthusiasts.

JAMA editors highlight top 2023 Clinical Reviews podcasts, including cirrhosis management, heart failure treatments, worsening US maternal death rates, and addressing obstetric racism.