Dr. Kirema Garcia-Reyes, an interventional radiologist from Mount Sinai specializing in Y90, joins Dr. Sabeen Dhand and Dr. Kevin Burns, an early adopter of histotripsy. They delve into the complexities of treating hepatocellular carcinoma (HCC) through ablation. Key insights include comparing cryoablation and microwave ablation, discussing histotripsy's noninvasive approach, and highlighting the significance of advanced imaging techniques. They also explore the future of curative therapies and the importance of patient-specific strategies in optimizing treatment outcomes.

Zachary Berman and Kirema Garcia-Reyes, interventional radiologists, share their expertise on Y-90 dosimetry, stressing that it's not a one-size-fits-all approach. They discuss factors influencing dosing, such as tumor size and underlying liver function. The guests reflect on gaps in training and the evolution of dosimetry education in interventional radiology. Real-life case examples illustrate the complexities of individualized treatment plans. They also critique planning software and underscore the importance of empirical approaches to achieve optimal dosages.

In this engaging discussion, medical oncologists Adam Burgoyne and Lingling Du, alongside interventional radiologists Kirema Garcia-Reyes and Zachary Berman, tackle the complexities of hepatocellular carcinoma (HCC) treatment. They explore the 'grey zone' in treatment goals, emphasizing the importance of performance status and comprehensive liver function assessments. The guests share insights on navigating advanced liver disease, the role of immunotherapy, and the critical need for multidisciplinary collaboration to optimize patient outcomes.