

Ep. 517 Complex HCC Patients and the "Grey Zone": What to Do When You Don’t Know What to Do
7 snips Feb 14, 2025
In this engaging discussion, medical oncologists Adam Burgoyne and Lingling Du, alongside interventional radiologists Kirema Garcia-Reyes and Zachary Berman, tackle the complexities of hepatocellular carcinoma (HCC) treatment. They explore the 'grey zone' in treatment goals, emphasizing the importance of performance status and comprehensive liver function assessments. The guests share insights on navigating advanced liver disease, the role of immunotherapy, and the critical need for multidisciplinary collaboration to optimize patient outcomes.
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Clinic Setting for Interventional Oncology
- Interventional radiologists specializing in oncology should see patients in a clinic setting.
- This allows for a better understanding of the patient's performance status and overall health.
BCLC Staging System
- The Barcelona-Clinic Liver Cancer (BCLC) staging system incorporates tumor characteristics and performance status.
- It has detailed guidance for early and advanced stages but less for the intermediate BCLC-B stage.
Performance Status Considerations
- Performance status is crucial when considering treatment options for HCC.
- Poor performance status due to tumor burden may improve with treatment, while pre-existing weakness might worsen.