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BackTable Vascular & Interventional

Ep. 517 Complex HCC Patients and the "Grey Zone": What to Do When You Don’t Know What to Do

Feb 14, 2025
In this engaging discussion, medical oncologists Adam Burgoyne and Lingling Du, alongside interventional radiologists Kirema Garcia-Reyes and Zachary Berman, tackle the complexities of hepatocellular carcinoma (HCC) treatment. They explore the 'grey zone' in treatment goals, emphasizing the importance of performance status and comprehensive liver function assessments. The guests share insights on navigating advanced liver disease, the role of immunotherapy, and the critical need for multidisciplinary collaboration to optimize patient outcomes.
39:35

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Quick takeaways

  • Performance status significantly influences treatment choices for hepatocellular carcinoma, affecting the balance between systemic and local therapies.
  • Multidisciplinary collaboration among oncologists and interventional radiologists enhances patient outcomes and facilitates effective communication in HCC management.

Deep dives

Determining Performance Status Impact

Performance status plays a crucial role in the treatment decisions for patients with hepatocellular carcinoma (HCC). Medical professionals assess whether a patient's performance status is declining due to tumor burden or due to pre-existing comorbidities. If performance status is poor, it can be challenging to improve it with aggressive local therapies, thus systemic therapy is often recommended. This approach aims to stabilize the patient’s health condition before potentially introducing more intensive treatments once performance improves.

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