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BackTable Vascular & Interventional
Ep. 515 Curative Intent Therapies for HCC: Today and Tomorrow
Feb 7, 2025
Dr. Kirema Garcia-Reyes, an interventional radiologist from Mount Sinai specializing in Y90, joins Dr. Sabeen Dhand and Dr. Kevin Burns, an early adopter of histotripsy. They delve into the complexities of treating hepatocellular carcinoma (HCC) through ablation. Key insights include comparing cryoablation and microwave ablation, discussing histotripsy's noninvasive approach, and highlighting the significance of advanced imaging techniques. They also explore the future of curative therapies and the importance of patient-specific strategies in optimizing treatment outcomes.
52:23
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Quick takeaways
- Selecting appropriate ablative therapies for hepatocellular carcinoma requires careful consideration of lesion size and location, particularly in BCLC Stage A patients.
- The podcast discusses the procedural complexities of Y90 radioembolization and innovative approaches to streamline treatment by combining mapping and therapy sessions.
Deep dives
Complexity of Ablative Modalities
The discussion highlights the complexity involved in selecting appropriate ablative modalities for liver tumors, particularly focusing on hepatocellular carcinoma (HCC). Decision-making is complicated by the availability of numerous treatment options including cryoablation, radiofrequency ablation, and emerging techniques like histotripsy. The need for comprehensive comparative trials to establish the superiority of one method over another is emphasized but deemed unlikely due to logistical challenges. The speaker acknowledges that with more options, choosing the most effective treatment becomes increasingly difficult.
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