In this podcast, Peter and Bob Kaplan discuss the importance of scientific literacy and the proper interpretation of studies. They cover topics such as study design, types of studies, clinical trials, statistical significance, and tips for reading scientific papers. They also explore the biases that can affect observational studies, discuss the concept of cluster randomization, and explain the difference between relative and absolute risk reduction. They emphasize the need for diligence and attention to detail when reading scientific studies, and provide a step-by-step guide for reading and understanding scientific papers.

In this engaging discussion, Bob Kaplan collaborates with Peter Attia, reflecting on evolving beliefs from their podcast journey. They delve into the transformation of Peter's views on metformin, rapamycin, and deadlifting, emphasizing the importance of adaptability in health perspectives. They also share the joy of Peter’s new puppy, explore the significance of Zone 2 training, and discuss how learning to say 'no' has impacted their lives. With insights on omega-3s and personal updates, this conversation offers a fascinating look at growth through dialogue.

In this “Ask Me Anything” (AMA) episode, Peter answers a wide range of questions from readers and podcast listeners. Bob Kaplan, Peter’s head analyst, asks the questions. This also marks the first video release of the podcast. You can find it on YouTube (https://youtu.be/kzs7GgxR_FQ) and the website (peterattiamd.com/ama03). If you have any questions for the next AMA, please submit them to the AMA section on the website (peterattiamd.com). We discuss: What references ranges does Peter consider too broad on lab tests? [5:30]; What aspect of women’s health is the least studied/understood? [21:15]; What are your thoughts on fasting and ketosis for females? [31:30]; Advice for medical students and residents, how to get through it, and optimize their time while in med school [38:00]; What is Peter’s opinion on the best way to monetize a podcast to make it sustainable? [47:45]; What are you looking to achieve and monitor with your blood glucose monitor? [57:15]; Thoughts on lithium supplementation? [1:08:15]; Insights about berberine? [1:16:00]; Why does Peter take a baby aspirin? What does the science say? [1:19:20]; How do you use HR variability as a metric in your practice and/or in your own personal use? Sleep, pre/post exercise, pre/post eating, every morning readiness? [1:23:25]; With the emergence of “the coconut oil is pure poison” article, can you shed some light on saturated fat in the literature and the types of studies done specifically on coconut oil? [1:38:45]; Would you discuss the recent meta studies that claim that moderate carbohydrate intake may be best for health? [1:40:45]; What is the number one recommendation/habit you would suggest every person add to their daily regimen (besides physical activity) for wholesome health? [1:42:45]; What does it mean if your body has a harder time getting into ketosis via fasting than it used to (testing using a Precision Xtra)? [1:44:15]; Why are you taking Zetia and Lipitor? Are you mitigating risk based on your APOE4? Or is there something else going on? [1:46:10]; What will your book be about and what is the expected release date? [1:47:45]; What are your thoughts on nicotinamide riboside supplementation for longevity? [1:49:30]; Which brand of supplements have you found to be effective? [1:54:30]; Are you currently accepting new patients? And how do I find a ‘Peter Attia clone’ in my area? [1:56:20]; Bob’s personal experience with Peter as a doctor [1:58:45]; Can you tell us more about the latest and best of APOE4? [2:06:15]; and More. Learn more at www.PeterAttiaMD.com Connect with Peter on Facebook| Twitter| Instagram.

In this “Ask Me Anything” (AMA) episode, Peter explains the various levers one can pull to affect longevity with a specific focus on the strategies and tactics one can implement that do not require the help of a physician. Once again, Bob Kaplan, Peter's head of research, will be asking the questions. If you’re not a subscriber and listening on a podcast player, you’ll only be able to hear a preview of the AMA. If you’re a subscriber, you can now listen to this full episode on your private RSS feed or on our website at the AMA #12 show notes page. We discuss: The five levers you can pull to affect longevity [1:15]; Nutritional biochemistry: Framework, 3 nutritional interventions, and how to approach your goals, and what you should be tracking [4:30]; Exercise for brain health, and the 4 components of exercise [20:45]; Exercise component—Stability [24:30]; Exercise component—Strength [29:00]; What is Peter optimizing for with his exercise? [30:30]; Exercise components—Zone 2 and zone 5 training [33:15]; More about DNS, and why we need to be careful with rushing kids through neuromuscular development stages [45:00]; Sleep: How to improve quantity and quality [48:15]; and More. Learn more: https://peterattiamd.com/ Show notes page for this episode:  https://peterattiamd.com/AMA12 Subscribe to receive exclusive subscriber-only content: https://peterattiamd.com/subscribe/ Sign up to receive Peter's email newsletter: https://peterattiamd.com/newsletter/ Connect with Peter on Facebook | Twitter | Instagram.

In this “Ask Me Anything” (AMA) episode, Peter answers a wide range of questions from subscribers. Bob Kaplan, Peter’s head of research, asks the questions. If you’re not a subscriber and listening on a podcast player, you’ll only be able to hear a preview of the AMA. If you’re a subscriber, you can now listen to this full episode on your private RSS feed. You can also watch (or listen) to this full episode on our website at the AMA #7 show notes page. Questions continue to be pulled from the AMA section on the website, and any subscriber is welcome to submit questions for future AMAs.   We discuss: What can I do to prevent/reduce interruptions in sleep due to needing to get up to urinate at night? [3:00]; Peter’s note card system for organizing his to-do lists [7:15]; How do I get smarter at reading/understanding the studies (or the media's interpretation of them) that get the headlines on health and/or disease? [11:15]; How can I obtain a continuous glucose monitor (CGM) as a non-diabetic individual? [11:55]; What is the most effective way to bring blood pressure down? [15:00]; Does Peter use any nootropics? [28:10]; Peter’s thoughts pertaining to concussions and head trauma [33:00]; Does Peter structure his exercise plan for lifespan or healthspan? [36:45]; How did Peter rebuild his lower back strength after his devastating injury during med school? [38:15]; Peter’s approach to deadlifting with a bad lower back [43:25]; Did Peter cave and buy a dog? [51:50]; and More. Learn more at www.PeterAttiaMD.com Connect with Peter on Facebook | Twitter | Instagram.