Alan Flanagan, an expert in chronobiology and chrononutrition, dives into the complexities surrounding omega-3 supplementation and its potential link to atrial fibrillation. He discusses how recent studies, including the controversial REDUCE-IT and STRENGTH trials, have raised concerns about the safety of omega-3s for heart health. Flanagan also emphasizes the importance of study design and methodology in interpreting these results, urging a cautious approach. The conversation navigates the fine line between benefits and risks of these popular supplements.

Alan Flanagan, an expert in chronobiology and nutrition, dives into the intricate relationship between IGF-1 and diet. They discuss how IGF-1 impacts growth, metabolic health, and its controversial links to cancer and cognitive decline. Listen in as they explore the challenges of using IGF-1 as a biomarker and the complexities of dietary influences on its levels. Flanagan also unpacks the nuances between total and free IGF-1, and what this means for diet and longevity.