Sigma Nutrition Radio
#538: Can Fish Oil Supplementation Increase Risk of Irregular Heart Rhythms?
Oct 8, 2024
Alan Flanagan, an expert in chronobiology and chrononutrition, dives into the complexities surrounding omega-3 supplementation and its potential link to atrial fibrillation. He discusses how recent studies, including the controversial REDUCE-IT and STRENGTH trials, have raised concerns about the safety of omega-3s for heart health. Flanagan also emphasizes the importance of study design and methodology in interpreting these results, urging a cautious approach. The conversation navigates the fine line between benefits and risks of these popular supplements.
55:03
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Quick takeaways
- Recent large-scale studies indicate a potential link between omega-3 supplementation and an increased risk of atrial fibrillation, raising safety concerns.
- The relationship between omega-3 fatty acids and cardiovascular health remains complex, necessitating individualized clinical decisions based on nuanced research findings.
Deep dives
Chronobiology and Meal Timing Research
Current research is exploring the synchronization of the body's central clock in the brain with meal timing, suggesting that under certain conditions, meal times could influence circadian rhythms. Previous studies in rodent models indicated that a significant energy deficit leads to the central clock synchronizing with meal timings rather than just the light-dark cycle. A planned human study aims to investigate this further using a controlled setting where participants will experience a prolonged state of wakefulness and chronic energy deficit. This innovative approach could enhance our understanding of how meal timing impacts metabolism and overall health.
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