The Jesse Chappus Show

675: Cardiologist Exposes the Top 5 Causes of Clogged Arteries: Do This to Prevent & Reverse | Dr. Michael Twyman

141 snips
Oct 21, 2025
Dr. Michael Twyman, a board-certified cardiologist and founder of Apollo Cardiology, dives deep into heart health this time. He explores the origins of atherosclerosis and the protective roles of nitric oxide and glycocalyx. Listeners learn how to stabilize and regress plaques and when to use medications versus lifestyle changes. Twyman also discusses the significance of lipoprotein(a), essential cardiovascular screening tests, and key dietary components for optimal vascular health. Practical advice for lifestyle modifications is a highlight!
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INSIGHT

Endothelium Is Where Plaque Begins

  • Endothelial dysfunction is the universal starting point for atherosclerosis.
  • Many risk factors (300–400) converge by damaging the arterial lining and initiating plaque.
INSIGHT

How Plaque Develops And Scars Over

  • Plaque forms when lipoproteins get retained and trigger inflammation and crystallization in the intima.
  • The body scars over plaques with smooth muscle and can even calcify them into bone-like deposits.
ADVICE

Fix Nitric Oxide And Glycocalyx First

  • First optimize the glycocalyx and nitric oxide to stop ongoing arterial damage.
  • Use exercise, nitrate-rich greens, and UVA sun exposure before targeting lipids aggressively.
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