The Jesse Chappus Show 675: Cardiologist Exposes the Top 5 Causes of Clogged Arteries: Do This to Prevent & Reverse | Dr. Michael Twyman
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Oct 21, 2025 Dr. Michael Twyman, a board-certified cardiologist and founder of Apollo Cardiology, dives deep into heart health this time. He explores the origins of atherosclerosis and the protective roles of nitric oxide and glycocalyx. Listeners learn how to stabilize and regress plaques and when to use medications versus lifestyle changes. Twyman also discusses the significance of lipoprotein(a), essential cardiovascular screening tests, and key dietary components for optimal vascular health. Practical advice for lifestyle modifications is a highlight!
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Lipoprotein(a) Is A Genetic Thrombotic Risk
- Lipoprotein(a) is largely genetic, present in everyone but elevated in ~20% and particularly prothrombotic.
- Serum Lp(a) test once in life is informative; few lifestyle changes reliably lower it.
Use Multi-Modal Vascular Screening
- Screen with carotid ultrasound, ankle-brachial index, central blood pressure, and CT coronary calcium when age or risk warrants.
- Use functional tests (pulse wave velocity, EndoPAT) to detect early endothelial dysfunction before symptoms arise.
Start Exercise Safely If Inactive
- If sedentary and unsure about risk, consult a physician and consider supervised exercise or stress testing first.
- Start gradual activity to stimulate nitric oxide and endothelial health while monitoring for symptoms.