
LONGEVITY with Nathalie Niddam #393: Laugh, Sweat, Detox: The Misunderstood Pathways to PEAK Health (Mitochondria, Doomscrolling, and Sex) With Dr. Ted Achacoso
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Dec 5, 2025 Join Dr. Ted Achacoso, a trailblazer in health optimization who blends neurology, pharmacology, and AI, as he redefines wellness. He shares how metabolomics can transform healthcare from a disease focus to a cell-centered approach. Hear about the unexpected insights from toxicity panels and his intriguing case study on mercury toxicity. Plus, the secrets of vitamin D's powerful role and practical daily habits for longevity are revealed, all sprinkled with humor and a refreshing focus on balance for a vibrant life.
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Cell Danger Response Is Metabolic
- Cells respond to stress through conserved, limited pathways driven by metabolites and reactive oxygen species.
- Measuring small-molecule metabolites reveals root causes of the cell danger response and guides treatment.
Shift From Organs To Cellular Networks
- Health optimization shifts focus from organs to cellular networks and metabolite balance.
- Treating cells' needs creates systemic improvements across organs and reduces polypharmacy.
Pescetarian With Mercury Damage
- A pescetarian developed arrhythmia, weakness, cognitive decline, and skin issues from chronic mercury exposure.
- Ted used metabolomics to diagnose mercury toxicity and reversed misguided specialist interventions with detoxification.

