The Neuro Experience #1 Orthopedic Surgeon: This is the Best Way for Women in Their 40's to Stay Strong | ft. Dr. Vonda Wright
Sep 2, 2025
Dr. Vonda Wright, a double-boarded orthopedic surgeon and advocate for active aging, discusses crucial health insights for women in their 40s. She explains how women can lose up to 20% of bone density during perimenopause and shares science-backed strategies to combat this decline. From the vital roles of hormones and exercise to the importance of specific nutrients, Dr. Wright emphasizes proactive measures for resilience and strength. She also touches on the connection between bone health and brain function, offering a holistic approach to well-being.
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Female Bone Loss Peaks In Midlife
- Women build peak bone mass by their mid-20s and then mostly maintain it until midlife.
- During perimenopause women can lose 15–20% bone density when estrogen declines, unlike men who decline ~1%/year.
Early Exposure And Research On Masters Athletes
- Vonda Wright grew up around endurance athletes and saw older people remain active and vital.
- Her research on masters athletes showed preserved bone, muscle, brain, and Clotho activation compared with sedentary peers.
Bone Is A Master Communicator
- Bones host hematopoiesis, store minerals, and act as a signaling organ across the body.
- Bone-derived signals influence distant organs including brain, gut, pancreas, testes, and muscle.
