Guest:
Dr. Kellen Cavagnero is a Postdoctoral Fellow at the University of California, San Diego. His PhD work focused on how fibroblasts — a cell type thought to be immunologically inert — contribute to chronic inflammatory conditions and defense against pathogens. He talks about staph infections, antimicrobial resistance, and the types and roles of fibroblasts. He also discusses his work in science communication, including his podcast, Inflammatory Content.
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The Immunology Science Round Up
Malaria Immunity – Scientists leveraged a human malaria infection study to investigate functional correlates of immunity.
CAR T Therapy for HIV – Anti-HIV-1 CAR-T cells armed with endogenic broadly neutralizing antibodies resulted in significant suppression of viral rebound in HIV patients.
Immunogenic Cell Death – Researchers generated a small-molecule proteolysis-targeting chimera that selectively degraded human and murine RIPK1.
Origins of Autoimmunity – NUDCD3 is required for healthy T and B cell development in humans.
Image courtesy of Dr. Kellen Cavagnero