18min chapter

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Ep. 79: “ILC2s, the Microbiome, and Fibroblasts” Featuring Dr. Kellen Cavagnero

The Immunology Podcast

CHAPTER

Unraveling RIPK1 and Immune Cell Development

This chapter explores the multifaceted role of RIPK1 in immune responses and cancer cell survival, focusing on a novel RIPK1-specific protac degrader that enhances anti-tumor activities. It also discusses significant findings from a study on severe combined immunodeficiency and its link to genetic mutations, elucidating their implications for immune cell function. The chapter highlights the importance of the NUDCD3 gene in T and B cell receptor recombination, drawing connections to immune-related disorders and potential treatment pathways.

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