The Internet Book of Critical Care Podcast IBCC Episode 52 Anticoagulation Reversal
10 snips
Aug 29, 2019 AI Snips
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Transcript
Episode notes
Interpreting INR/PTT Variably
- INR and PTT interpretation depends on the cause of coagulopathy and medication involved.
- INR is reliable for warfarin but not for cirrhosis or other anticoagulants.
Key Anticoagulation Reversal Considerations
- Consider the patient's anticoagulation reason and drug timing before reversal.
- Tailor reversal approach to drug type, bleeding severity, and coagulopathy status.
Warfarin Urgent Reversal Strategy
- For urgent warfarin reversal, give 10 mg IV vitamin K and four-factor PCC or FFP simultaneously.
- Avoid giving PCC/FFP alone without vitamin K to prevent rebound anticoagulation.