The Curious Clinicians

56 - Trigging Out

Sep 2, 2022
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ANECDOTE

Morning Report Case

  • Avi Cooper recalls a morning report case of severe pancreatitis caused by extremely high triglyceride levels.
  • The focus was on therapies like insulin and apheresis, but Avi wondered about the link between triglycerides and pancreatitis.
INSIGHT

Triglycerides and Pancreatitis Link

  • The link between lipids and pancreatitis was proposed in 1865, but the specific triglyceride link wasn't until 1975.
  • A study in the journal 'Surgery' found that high triglyceride levels induced pancreatitis in patients with a history of alcohol-related pancreatitis.
INSIGHT

Triglyceride Levels and Pancreatitis Risk

  • Raising serum triglycerides appears to cause pancreatitis.
  • A dose-response relationship exists between triglyceride levels and pancreatitis risk, increasing significantly above 1000 mg/dL.
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