
Extend Podcast with Darshan Shah, MD 108. Dr. Vonda Wright: Why Women Need a New Approach to Aging, and How to Start Now
Oct 30, 2025
Dr. Vonda Wright, a double board-certified orthopedic surgeon and author of Unbreakable, shares her expertise on active aging and preventive strategies for women. She emphasizes that proactive health measures should start in the 30s and 40s, well before menopause. Vonda discusses how declining estradiol affects bone and brain health, and highlights biomarkers like VO₂ max and grip strength to predict longevity. Her FACE framework outlines essential training pillars for preserving mobility and strength, ensuring women can thrive through midlife.
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Midlife Shift Begins Before Menopause
- Women experience a seismic shift in aging a decade before menopause due to falling estradiol.
- This early change accelerates brain, heart microvascular, and bone deterioration silently.
Rapid Bone Loss In Perimenopause
- During perimenopause bone loss triples from ~1% to ~3% per year.
- Ignoring five to seven years can erase roughly 20% of bone density before diagnosis.
Begin Prevention By Age 30
- Start prevention in your 30s or when you decide you’re done having children.
- Build an 'unbreakable' lifestyle with anti-inflammatory eating, strength training, and cardio structure.



