LONGEVITY with Nathalie Niddam #392: Biohacking the MIND: 78% Anxiety Remission, Vagus Nerve Secrets & The Mental Health Revolution | Zenbud's Jon Hacker Unlocks REST
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Dec 2, 2025 Join Jon Hacker, an entrepreneur and biohacker specializing in mental health technology, as he delves into his journey from battling OCD to revolutionizing anxiety treatments. He discusses the skyrocketing anxiety rates attributed to modern tech and chronic stress's impact on health. Jon introduces vagus nerve stimulation with his ZenBud headset, offering a gentler alternative to traditional methods, achieving around 78% anxiety remission. He emphasizes the importance of mindfulness and purpose while exploring the future of biohacking and AI in mental health.
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Personal Origin Story
- Jon Hacker grew up with severe OCD and nearly reached the brink several times as a child.
- That personal struggle motivated him to develop tools freeing people from debilitating anxiety.
Attention Economies Fuel Anxiety
- Modern attention-driven systems intentionally amplify sympathetic (fight-or-flight) activation to capture users.
- That engineered activation is a core driver of rising anxiety in society today.
Chronic Stress Accelerates Biological Decline
- Chronic sympathetic activation breaks the body down via elevated cortisol, impaired recovery, weight gain, and higher blood sugar.
- Living in a near-constant fight-or-flight accelerates decline and worsens longevity outcomes.