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Bladder problems, such as urinary urgency, leaky bladder, incomplete urination, or frequent urination, are often linked to a deficiency in vitamin B1. The nervous system, particularly the peri aqueductal gray matter in the brain, plays a crucial role in controlling the bladder. A thiamine deficiency can affect this part of the brain and the autonomic nervous system, leading to bladder dysfunction. This deficiency is especially prevalent in individuals with diabetes, where around 50 to 70% experience bladder issues. B1 is important for nerve function and energy production, particularly in the presence of carbohydrates or glucose. Correcting the B1 deficiency through supplementation and adopting a low-carb diet can significantly improve bladder problems.