

BITESIZE | 3 Steps to Reverse Ageing and Live Longer | Professor David Sinclair #293
Sep 8, 2022
David Sinclair, a renowned biologist and Harvard professor, dives into the secrets of aging and longevity. He explores the concept of hormesis, explaining how embracing controlled stressors like exercise and fasting can activate our longevity genes. Sinclair advocates for caloric restriction to promote healthier aging, alongside the benefits of high-intensity workouts. He also addresses the importance of a positive mindset, sharing inspiring stories that redefine aging, and emphasizing that vitality can flourish well into our 80s.
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Hormesis and Modern Comfort
- Modern comfort hinders our bodies' natural defenses against aging.
- We must introduce hormesis, "what doesn't kill you makes you stronger," by mimicking challenges like cold and hunger.
Eat Less Often
- Eat less often to activate longevity genes and live healthier, longer lives.
- Mimic the study's mice who ate within a restricted time window, regardless of food type, and lived longer.
Simplify Intermittent Fasting
- Simplify intermittent fasting or time-restricted eating by just eating less frequently.
- Skip meals, starting with one, and gradually increase the duration, allowing your body to adapt.