Explore the fascinating world of hormones, from their crucial role in coordinating human physiology to their influence on puberty, menopause, stress response, and weight regulation. Learn about the intricate interactions of hormones in maintaining balance and how they impact our health and wellbeing. Delve into the challenges posed by endocrine disruptors in pregnancy and the potential for personalized hormone treatments. Discover the evolutionary perspectives on hormone systems and the brain's response to hormonal signals.
Hormones regulate essential bodily functions like metabolism and growth through complex signaling pathways.
Different endocrine glands produce specific hormones, coordinating behavior and health across species.
The pituitary gland and hypothalamus act as crucial regulators, maintaining hormone levels for optimal bodily function like a thermostat.
Deep dives
Hormones: The Body's Chemical Messengers
Hormones are essential chemical signals within our bodies, regulating various functions from metabolism to growth. They are produced by endocrine glands and play a crucial role in physiology, growth, and immune responses. Hormones act by binding to specific receptors on cells, triggering a chain reaction that influences gene regulation and cellular signaling.
Endocrine Glands and Hormone Production
Hormones are produced by endocrine glands such as the thyroid, ovaries, and testes, as well as cells in the gut and fat tissues. Different cells in specific locations produce distinct hormones for various bodily functions. These hormones play a fundamental role in coordinating behavior, physiology, and overall health across different species.
Pituitary Gland and Hormone Regulation
The pituitary gland and hypothalamus serve as key controllers of the endocrine system, orchestrating the production of hormones from various glands. The pituitary gland releases stimulating hormones that regulate other glands, while the hypothalamus integrates signals and influences hormone release. This intricate system functions akin to a thermostat, maintaining hormone levels for optimal bodily function.
Synthesizing Hormones for Medicinal Uses
Synthetic hormones have been developed for medical treatments, such as insulin for diabetes and growth hormone for growth disorders. These hormones can be derived from animal tissues or synthesized in bacteria to ensure purity and effectiveness. Advances in hormone treatments offer tailored solutions for hormone-related conditions, promoting better health outcomes.
Impact of Hormones on Health and Behavior
Hormones have far-reaching effects on health, behavior, and development throughout life, influencing aspects like mood, appetite, and growth. The intricate interplay of hormones during pregnancy shapes fetal development and lifelong health outcomes. Hormones regulate vital systems in the body and play a role in conditions like obesity, stress responses, and endocrine disorders.
Melvyn Bragg and guests discuss some of the chemical signals coursing through our bodies throughout our lives, produced in separate areas and spreading via the bloodstream. We call these 'hormones' and we produce more than 80 of them of which the best known are arguably oestrogen, testosterone, adrenalin, insulin and cortisol. On the whole hormones operate without us being immediately conscious of them as their goal is homeostasis, maintaining the levels of everything in the body as required without us having to think about them first. Their actions are vital for our health and wellbeing and influence many different aspects of the way our bodies work.
With
Sadaf Farooqi
Professor of Metabolism and Medicine at the University of Cambridge
Rebecca Reynolds
Professor of Metabolic Medicine at the University of Edinburgh
And
Andrew Bicknell
Associate Professor in the School of Biological Sciences at the University of Reading
Produced by Victoria Brignell
Reading list:
Rachel Carson, Silent Spring (first published 1962; Penguin Classics, 2000)
Stephen Nussey and Saffron Whitehead, Endocrinology: An Integrated Approach (BIOS Scientific Publishers; 2001)
Aylinr Y. Yilmaz, Comprehensive Introduction to Endocrinology for Novices (Independently published, 2023)
Get the Snipd podcast app
Unlock the knowledge in podcasts with the podcast player of the future.
AI-powered podcast player
Listen to all your favourite podcasts with AI-powered features
Discover highlights
Listen to the best highlights from the podcasts you love and dive into the full episode
Save any moment
Hear something you like? Tap your headphones to save it with AI-generated key takeaways
Share & Export
Send highlights to Twitter, WhatsApp or export them to Notion, Readwise & more
AI-powered podcast player
Listen to all your favourite podcasts with AI-powered features
Discover highlights
Listen to the best highlights from the podcasts you love and dive into the full episode