Pharmacy to Dose: The Critical Care Podcast cover image

Pharmacy to Dose: The Critical Care Podcast

Acid-Base Disorders in the Critically Ill

Oct 7, 2024
In this engaging discussion, Justin Muir, a critical care pharmacist and co-author of an insightful review article on acid-base disorders, joins Judah Brown, an emergency medicine pharmacy manager also involved in the article. They dive into the complexity of interpreting acid-base status, emphasizing the stepwise approach to arterial blood gas assessment. The duo explores the nuanced treatment of metabolic acidosis and the efficacy of buffering agents like Acetazolamide. Listeners will appreciate the mnemonics and practical insights shared, enhancing their understanding of vital clinical concepts.
01:02:07

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Quick takeaways

  • A systematic approach to analyzing acid-base disorders includes using three primary methods: the Henderson-Hasselbalch equation, base excess and deficit, and the strong ion approach.
  • Interpreting arterial blood gases in a five-step process helps clinicians identify acid-base imbalances and their compensatory mechanisms in critically ill patients.

Deep dives

Understanding Acid-Base Disorders

Acid-base balance is crucial in clinical practice, particularly in critical care settings. The podcast features a discussion on a systematic approach to understanding acid-base disorders, emphasizing the complexity of the topic. Both emergency medicine and critical care perspectives are presented, making the information accessible for diverse audiences, including new practitioners and students. The hosts highlight the importance of applying theoretical knowledge to real patient scenarios, as many practitioners struggle to translate basic science into clinical application.

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