Pharmacy to Dose: The Critical Care Podcast

Kristen Sherlin, a critical care–trained pharmacist and RSI trial author, shares her role as a site investigator and how pharmacists integrated into a large pragmatic randomized trial. She describes ED workflow, kit setup, bedside randomization, team buy-in, and how trial participation changed practice and raised new research questions.

Special Guests: Matthew Semler, MD & Nicole Acquisto, PharmD, FASHP, FCCM, FCCP Join us as we do a deep dive into the RSI trial, published in NEJM in Dec 2025. Previous RCTs, study development timeline, guideline recommendations, study methodology and findings, answering listener questions, clearing up internet rumors, how to apply these findings, significant secondary outcome?, next steps, fun facts, and so much more. RSI Trial: https://pubmed.ncbi.nlm.nih.gov/41369227/ Episode Reference List: https://pharmacytodose.wordpress.com/wp-content/uploads/2026/01/rsi-trial-deep-dive-references.pdf @PharmacyToDose Pharmacytodose@gmail.com Pharmacytodose.com Learn more about your ad choices. Visit megaphone.fm/adchoices

2025 ACCP Annual Meeting Recap   Reliving the 2025 ACCP Annual Meeting as Conference Correspondent Anthony Hawkins and I recap everything that happened in Minneapolis, MN   Special guest: Anthony Hawkins, PharmD, BCCCP, FCCM, FCCP   @Pharmacytodose Pharmacytodose@gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Three new Fellows of ACCP (FCCP) join to discuss their journey, the application, things they learned, advice, a hearty congratulations, and so much more! Special guests: Christine Groth, PharmD, FCCM, FCCP, BCCCP Philip King, PharmD, BCPS, FCCP Anthony Hawkins, PharmD, BCCCP, FCCM, FCCP https://www.accp.com/meetings/am25/index.aspx @PharmacyToDose Pharmacytodose@gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

2025 ACCP Annual Meeting Highlights: Elevating Clinical Pharmacy in the ICU   Highlighting a 2025 ACCP Annual Meeting educational session as well as a financial opportunity available to all Critical Care PRN members.     01:30 – Highlighting the Consensus Recommendations for Integrating Critical Care Pharmacists on ICU Teams Featuring: Mojdeh Heavner, PharmD, FCCP, FCCM, BCCCP Susan Smith, PharmD, FCCM Brian Murray, PharmD, BCCCP Andrea Sikora, PharmD, FCCP, FCCM, BCCCP   https://accpjournals.onlinelibrary.wiley.com/doi/10.1002/jac5.70084   39:40 – Critical Care PRN Multicenter Research Network (MRN) Grant Featuring: Julie Farrar, PharmD, BCCCP   @Pharmacytodose Pharmacytodose@gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

2025 ACCP Annual Meeting Highlights: Neuromuscular Blocking Agents & Ketamine   Highlighting two education sessions from the 2025 ACCP Annual Meeting in today’s daily recap.   01:25 – Neuromuscular Blocking Agents in the Critical Care Setting Featuring: Scott Benken, PharmD, MHPE, FCCP, FCCM, BCCCP, BCPS Megan Rech, PharmD, Masters in Research, FCCP, FCCM, BCCCP Julie DiBridge Clarkson, PharmD, BCCCP, BCCP, BCPS Eric Johnson, PharmD, MBA, BCCCP   39:50 – Use of Ketamine Across Multiple Practice Areas Featuring: Leslie Hamilton, PharmD, FCCP, BCCCP, BCPS David Zimmerman, PharmD, FASHP, FCCP, BCCCP, BCEMP https://www.accp.com/meetings/am25/index.aspx   @Pharmacytodose Pharmacytodose@gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

2025 ACCP Annual Meeting Highlights: AI and Hyperthermia   Today’s daily episode from the 2025 ACCP Annual Meeting highlights two different educational sessions.   01:40 – Management of Drug-Induced Hyperthermia Featuring: Megan Musselman, PharmD, FCCP, FASHP, BCCCP, BCEMP Ruben Santiago, PharmD, BCCCP, BCEMP, BCPS   22:00 – Artificial Intelligence as Your Co-Pilot Featuring: Zac Noel, PharmD, PhD, BCCP Abby Krauter, PharmD, BCPS Scott Nei, PharmD, BCPS, BCCCP, FCCM, FMSHP Kaitlin Alexander, PharmD, BCCCP   https://www.accp.com/meetings/am25/index.aspx   @Pharmacytodose Pharmacytodose@gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Conference Correspondent, Anthony Hawkins, returns to the podcast to preview the 2025 ACCP Annual Meeting in Minneapolis, MN. Session highlights, conference advice, Minneapolis review, and much more! https://www.accp.com/meetings/am25/index.aspx @PharmacyToDose Pharmacytodose@gmail.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Natalia Smith, a critical care pharmacist transitioning to an ICU role, shares insights on using dexmedetomidine to improve sleep in the ICU. She discusses its mechanism, potential benefits for sleep architecture, and practical dosing strategies. Alyson DeRosa, a PGY2 resident, explores dexmedetomidine's role in managing alcohol withdrawal syndrome, emphasizing its limitations and safety concerns. Together, they highlight the importance of combining dexmedetomidine with traditional therapies while monitoring for adverse effects.

Sean Chi, an emergency medicine pharmacist, shares insights on using vasopressors after cardiac arrest, discussing critical management strategies for hypotension. Eric Pham, a critical care pharmacy resident, presents the use of Midodrine for weaning vasopressors in sepsis and shock, highlighting its advantages and challenges. The conversation delves into the complexities of balancing pharmacological approaches with clinical outcomes, emphasizing the importance of tailored treatment plans for critically ill patients.