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Huberman Lab

The Science of MDMA & Its Therapeutic Uses: Benefits & Risks

Jun 12, 2023
02:13:42

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Quick takeaways

  • MDMA, also known as ecstasy or molly, has unique effects on brain function and connectivity, reducing threat detection and enhancing social engagement and empathy.
  • The legal status of MDMA plays a significant role in understanding its current use and potential therapeutic applications.

Deep dives

MDMA is a unique compound that has properties similar to methamphetamine and distinct properties related to the release of serotonin.

MDMA, also known as ecstasy or molly, is a synthetic compound that has similarities to methamphetamine in terms of dopaminergic effects but also controls the release of serotonin. This distinction makes MDMA different from classic psychedelics and pure stimulants. The combination of increased dopamine and serotonin levels creates empathogenic effects, enhancing social connectedness and empathy for oneself and others. This distinctive property of MDMA has led to both recreational use and promising results in clinical trials, particularly for the treatment of PTSD.

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